Colm Andrews
YOU?
Author Swipe
View article: Outpatient hospital attendances in people with rheumatoid arthritis during the COVID-19 pandemic and beyond: a cohort study in three nations of the UK
Outpatient hospital attendances in people with rheumatoid arthritis during the COVID-19 pandemic and beyond: a cohort study in three nations of the UK Open
Objectives We aimed to estimate how rheumatology outpatient hospital attendances have changed since the COVID-19 pandemic and determine demographic characteristics associated with observed changes. Methods Using three primary and secondary…
View article: Recording of Pharmacy First consultations in general practice records in England: an observational study of the service's first year using OpenSAFELY
Recording of Pharmacy First consultations in general practice records in England: an observational study of the service's first year using OpenSAFELY Open
Background: Pharmacy First, a national community pharmacy service, launched in January 2024 to improve access to primary care for patients with minor conditions facing backlogs caused by the COVID-19 pandemic. Pharmacies are required to sh…
View article: OpenSAFELY: Effectiveness of COVID-19 Vaccination in Children and Adolescents
OpenSAFELY: Effectiveness of COVID-19 Vaccination in Children and Adolescents Open
Background: We assessed the safety and effectiveness of the first- and second-dose BNT162b2 COVID-19 vaccination, offered as part of the national COVID-19 vaccine roll-out from September 2021, in children and adolescents in England. Method…
View article: Uptake of service specific codes for the COVID oximetry @Home Pulse Oximetry service: an analysis of 57 million patients' primary care records using OpenSAFELY (Preprint)
Uptake of service specific codes for the COVID oximetry @Home Pulse Oximetry service: an analysis of 57 million patients' primary care records using OpenSAFELY (Preprint) Open
BACKGROUND NHS England guidance was issued in November 2020 for use of COVID Oximetry @home (informally named CO@h) to detect early deterioration of patients with COVID-19 in primary and community care settings. OBJECTIVE We set out to …
View article: Uptake of service specific codes for the COVID oximetry @Home Pulse Oximetry service: an analysis of 57 million patients’ primary care records using OpenSAFELY
Uptake of service specific codes for the COVID oximetry @Home Pulse Oximetry service: an analysis of 57 million patients’ primary care records using OpenSAFELY Open
Background NHS England guidance was issued in November 2020 for use of COVID Oximetry @home (informally named CO@h) to detect early deterioration of patients with COVID-19 in primary and community care settings. Methods With the approval o…
View article: Impact of the COVID-19 pandemic on antidepressant prescribing with a focus on people with learning disability and autism: an interrupted time series analysis in England using OpenSAFELY-TPP
Impact of the COVID-19 pandemic on antidepressant prescribing with a focus on people with learning disability and autism: an interrupted time series analysis in England using OpenSAFELY-TPP Open
Background COVID-19 restrictions led to increased reports of depressive symptoms in the general population and impacted health and social care services. We explored whether these changes affected antidepressant prescribing trends in the ge…
View article: The NHS England Jewish BRCA Testing Programme: overview after first year of implementation (2023–2024)
The NHS England Jewish BRCA Testing Programme: overview after first year of implementation (2023–2024) Open
Background The NHS Jewish BRCA Testing Programme is offering germline BRCA1 and BRCA2 genetic testing to people with ≥1 Jewish grandparent. Who have an increased likelihood of having an Ashkenazi Jewish (AJ) founder germline pathogenic var…
View article: COVID-19 and Mental Illnesses in Vaccinated and Unvaccinated People
COVID-19 and Mental Illnesses in Vaccinated and Unvaccinated People Open
Importance Associations have been found between COVID-19 and subsequent mental illness in both hospital- and population-based studies. However, evidence regarding which mental illnesses are associated with COVID-19 by vaccination status in…
View article: Impact of COVID-19 on recorded blood pressure screening and hypertension management in England: an analysis of monthly changes in the quality and outcomes framework indicators in OpenSAFELY
Impact of COVID-19 on recorded blood pressure screening and hypertension management in England: an analysis of monthly changes in the quality and outcomes framework indicators in OpenSAFELY Open
Background The COVID-19 pandemic disrupted cardiovascular disease management in primary care in England. Objective To describe the impact of the pandemic on blood pressure screening and hypertension management based on a national quality o…
View article: Incidence of diabetes after SARS-CoV-2 infection in England and the implications of COVID-19 vaccination: a retrospective cohort study of 16 million people
Incidence of diabetes after SARS-CoV-2 infection in England and the implications of COVID-19 vaccination: a retrospective cohort study of 16 million people Open
UK National Institute for Health and Care Research, UK Research and Innovation (UKRI) Medical Research Council, UKRI Engineering and Physical Sciences Research Council, Health Data Research UK, Diabetes UK, British Heart Foundation, and th…
View article: Effectiveness of mRNA COVID-19 Vaccines as First Booster Doses in England: An Observational Study in OpenSAFELY-TPP
Effectiveness of mRNA COVID-19 Vaccines as First Booster Doses in England: An Observational Study in OpenSAFELY-TPP Open
Background: The UK delivered its first “booster” COVID-19 vaccine doses in September 2021, initially to individuals at high risk of severe disease, then to all adults. The BNT162b2 Pfizer-BioNTech vaccine was used initially, then also Mode…
View article: <scp>OpenSAFELY</scp>: A platform for analysing electronic health records designed for reproducible research
<span>OpenSAFELY</span>: A platform for analysing electronic health records designed for reproducible research Open
Electronic health records (EHRs) and other administrative health data are increasingly used in research to generate evidence on the effectiveness, safety, and utilisation of medical products and services, and to inform public health guidan…
View article: OpenSAFELY: Effectiveness of COVID-19 vaccination in children and adolescents
OpenSAFELY: Effectiveness of COVID-19 vaccination in children and adolescents Open
Background Children and adolescents in England were offered BNT162b2 as part of the national COVID-19 vaccine roll out from September 2021. We assessed the safety and effectiveness of first and second dose BNT162b2 COVID-19 vaccination in …
View article: The impact of the COVID-19 pandemic on Antidepressant Prescribing with a focus on people with learning disability and autism: An interrupted time-series analysis in England using OpenSAFELY-TPP
The impact of the COVID-19 pandemic on Antidepressant Prescribing with a focus on people with learning disability and autism: An interrupted time-series analysis in England using OpenSAFELY-TPP Open
Background COVID-19 lockdowns led to increased reports of depressive symptoms in the general population and impacted the health and social care services of people with learning disability and autism. We explored whether the COVID-19 pandem…
View article: P086 Trends in the Incidence and Management of Gout in England: A Nationwide Study using the OpenSAFELY Platform
P086 Trends in the Incidence and Management of Gout in England: A Nationwide Study using the OpenSAFELY Platform Open
Background/Aims Gout is the most common inflammatory arthritis worldwide, yet one of the worst managed. Few population-level studies have evaluated how the COVID-19 pandemic impacted on incidence, prevalence, management and hospitalisation…
View article: The impact of COVID‐19 on medication reviews in English primary care. An OpenSAFELY‐TPP analysis of 20 million adult electronic health records
The impact of COVID‐19 on medication reviews in English primary care. An OpenSAFELY‐TPP analysis of 20 million adult electronic health records Open
Aims The COVID‐19 pandemic caused significant disruption to routine activity in primary care. Medication reviews are an important primary care activity ensuring safety and appropriateness of prescribing. A disruption could have significant…
View article: Comparative safety and effectiveness of Pfizer BA.4-5 versus Sanofi during the spring 2023 COVID-19 booster vaccination programme in England: a matched cohort study in OpenSAFELY-TPP
Comparative safety and effectiveness of Pfizer BA.4-5 versus Sanofi during the spring 2023 COVID-19 booster vaccination programme in England: a matched cohort study in OpenSAFELY-TPP Open
Introduction The spring 2023 COVID-19 booster vaccination programme in England used both Pfizer BA.4-5 and Sanofi vaccines. All people aged 75 years or over and the clinically vulnerable were eligible to receive a booster dose. Direct comp…
View article: During the <scp>COVID</scp> ‐19 pandemic 20 000 prostate cancer diagnoses were missed in England
During the <span>COVID</span> ‐19 pandemic 20 000 prostate cancer diagnoses were missed in England Open
Objectives To investigate the effect of the COVID‐19 pandemic on prostate cancer incidence, prevalence, and mortality in England. Patients and Methods With the approval of NHS England and using the OpenSAFELY‐TPP dataset of 24 million pati…
View article: Changes in opioid prescribing during the COVID-19 pandemic in England: cohort study of 20 million patients in OpenSAFELY-TPP
Changes in opioid prescribing during the COVID-19 pandemic in England: cohort study of 20 million patients in OpenSAFELY-TPP Open
Background The COVID-19 pandemic disrupted healthcare delivery, including difficulty accessing in-person care, which may have increased the need for strong pharmacological pain relief. Methods With NHS England approval, we used routine cli…
View article: OpenSAFELY: Measuring BMI in 22 million patients in England
OpenSAFELY: Measuring BMI in 22 million patients in England Open
Background Body mass index (BMI) has been identified as a risk factor for clinical outcomes in patients with COVID-19. Studies identifying this risk have used electronic health record (EHR) platforms in which clinical conditions must be pr…
View article: Clinical and health inequality risk factors for non-COVID-related sepsis during the global COVID-19 pandemic: a national case-control and cohort study
Clinical and health inequality risk factors for non-COVID-related sepsis during the global COVID-19 pandemic: a national case-control and cohort study Open
The UK Health Security Agency, Health Data Research UK, and National Institute for Health Research.
View article: Consistency, completeness and external validity of ethnicity recording in NHS primary care records: a cohort study in 25 million patients’ records at source using OpenSAFELY
Consistency, completeness and external validity of ethnicity recording in NHS primary care records: a cohort study in 25 million patients’ records at source using OpenSAFELY Open
Background Ethnicity is known to be an important correlate of health outcomes, particularly during the COVID-19 pandemic, where some ethnic groups were shown to be at higher risk of infection and adverse outcomes. The recording of patients…
View article: Impact of the COVID-19 pandemic on antipsychotic prescribing in individuals with autism, dementia, learning disability, serious mental illness or living in a care home: a federated analysis of 59 million patients’ primary care records in situ using OpenSAFELY
Impact of the COVID-19 pandemic on antipsychotic prescribing in individuals with autism, dementia, learning disability, serious mental illness or living in a care home: a federated analysis of 59 million patients’ primary care records in situ using OpenSAFELY Open
Background The COVID-19 pandemic affected how care was delivered to vulnerable patients, such as those with dementia or learning disability. Objective To explore whether this affected antipsychotic prescribing in at-risk populations. Metho…