C. Aengus Murphy
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View article: Short-term and long-term outcome prediction for patients with coronary artery disease using machine learning and comprehensive multi-center patient data
Short-term and long-term outcome prediction for patients with coronary artery disease using machine learning and comprehensive multi-center patient data Open
Background Revascularization decision-making for patients with coronary artery disease (CAD) can benefit from accurate patient outcome prediction. While previous studies have employed data-driven methods including machine learning (ML) to …
View article: The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification
The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification Open
Dynasore prevents ZOL-induced viability loss in HGFs by partially interfering with macropinocytosis and by inhibiting the endosomal maturation pathway thought to be needed for ZOL delivery to the cytoplasm.
View article: 802 CONCURRENT PATHOLOGIES OBSERVED IN OLDER ADULTS WITH COVID-19 INFECTION
802 CONCURRENT PATHOLOGIES OBSERVED IN OLDER ADULTS WITH COVID-19 INFECTION Open
Introduction This study aimed to look at the effect of frailty and multi morbidity on short-term outcomes in patients diagnosed with COVID-19 in a hospital setting, looking specifically at the variety of concurrent pathologies diagnosed du…
View article: 30 Syntax score- a simple way to stratify complex coronary disease?
30 Syntax score- a simple way to stratify complex coronary disease? Open
Background The Syntax Score (SS) is an angiographic risk stratification tool to grade coronary disease complexity and aid revascularisation strategy decision making. Calculated scores are divided into tertiles (0–22, 23–32, >32) and guidel…
View article: Twiddler's syndrome: a rare cause of implantable cardioverter defibrillator malfunction
Twiddler's syndrome: a rare cause of implantable cardioverter defibrillator malfunction Open
A 63-year-old female received an implantable cardioverter defibrillator having been resuscitated from an out-of-hospital (ventricular fibrillation) cardiac arrest. She had pre-existent diagnoses of left ventricular dysfunction (ejection fr…