Colm Power
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View article: Survival Outcomes in Breast Cancer Patients With Metastatic Bone Disease
Survival Outcomes in Breast Cancer Patients With Metastatic Bone Disease Open
Objective To evaluate the survival outcomes of breast cancer patients with metastatic bone disease and to assess whether these patients exhibit different prognoses compared to those with more extensive metastatic involvement. Background Sy…
View article: Prognostic Significance of Delays in Initiation of Adjuvant Trastuzumab-Based Therapy in Patients with HER2-Positive Breast Cancer
Prognostic Significance of Delays in Initiation of Adjuvant Trastuzumab-Based Therapy in Patients with HER2-Positive Breast Cancer Open
Purpose: Adjuvant trastuzumab therapy has improved outcomes in HER2-positive breast cancer, but the impact of the timing of its initiation remains unclear. This study evaluates the effect of time to adjuvant trastuzumab-based therapy (TTAT…
View article: Wire-guided localisation vs HOLOGIC® LOCalizer™ radiofrequency identification (RFID) tag localisation of non-palpable breast lesions; a comparative analysis of ease of use and accuracy of localisation
Wire-guided localisation vs HOLOGIC® LOCalizer™ radiofrequency identification (RFID) tag localisation of non-palpable breast lesions; a comparative analysis of ease of use and accuracy of localisation Open
While associated with fewer positive margins, tag localisation did not significantly lower re-excision rates and was more likely to fail than wire-guided localisation. Further studies may elucidate its possible benefits in select patients.
View article: 134 Laparoscopic-assisted Transversus Abdominis Plane Block versus Port-site Infiltration in Appendectomy: A Multicentre Randomised Controlled Trial
134 Laparoscopic-assisted Transversus Abdominis Plane Block versus Port-site Infiltration in Appendectomy: A Multicentre Randomised Controlled Trial Open
Introduction Transversus abdominis plane (TAP) block has been shown to be an effective technique in providing post-operative analgesia across a range of intra-abdominal surgeries. Laparoscopic-assisted TAP (LTAP) block is a recent advancem…
View article: Taxane-based chemotherapy-induced peripheral neuropathy: a prospective cohort study
Taxane-based chemotherapy-induced peripheral neuropathy: a prospective cohort study Open
Objective: Chemotherapy-induced peripheral neuropathy is a debilitating neurotoxic side effect of chemotherapy. Painful symptoms of CIPN can be chronic for cancer patients or survivors and limit their quality of life. Currently, chemothera…
View article: Does Sentinel Lymph Node Biopsy Influence Subsequent Management Decisions in Women With Breast Cancer ≥ 70 Years Old?
Does Sentinel Lymph Node Biopsy Influence Subsequent Management Decisions in Women With Breast Cancer ≥ 70 Years Old? Open
In this study, SLNB did not significantly influence subsequent management decisions in patients over 80 and should rarely be performed in this cohort. However, SLNB still had a role in patients aged 70-80 and should be used selectively in …
View article: A bibliometric analysis of HER2-positive breast cancer: 1987–2024
A bibliometric analysis of HER2-positive breast cancer: 1987–2024 Open
Aim The overamplification of human epidermal growth factor (HER2) in breast cancer (BC) has been the subject of numerous research publications since its discovery in 1987. This is the first bibliometric analysis (BA) conducted on HER2-posi…
View article: AB026. SOH24AB_045. Knowledge of BRCA1/BRCA2 pathogenic variant status in a non-Ashkenazi Jewish cohort is important for survival
AB026. SOH24AB_045. Knowledge of BRCA1/BRCA2 pathogenic variant status in a non-Ashkenazi Jewish cohort is important for survival Open
Background: BRCA1/2 pathogenic variant carriers have a higher lifetime risk of developing breast cancer. Risk-management options include breast surveillance or bilateral prophylactic mastectomy (BPM). The aim of this study was to assess if…
View article: AB141. SOH24AB_151. Breast implant associated anaplastic large cell lymphoma (BIA-ALCL): a case study
AB141. SOH24AB_151. Breast implant associated anaplastic large cell lymphoma (BIA-ALCL): a case study Open
Background: Breast implant associated anaplastic large cell lymphoma (BIA-ALCL) is a rare form of non-Hodgkin's T-cell lymphoma associated with textured breast implants and tissue expanders first described in 1997 and categorised as a dist…
View article: Monopolar diathermy <i>versus</i> a vessel-sealing device for reducing postoperative drain output after simple mastectomy: randomized clinical trial
Monopolar diathermy <i>versus</i> a vessel-sealing device for reducing postoperative drain output after simple mastectomy: randomized clinical trial Open
Background Electrosurgical devices are commonly used during mastectomy for simultaneous dissection and haemostasis, and can provide potential benefits regarding vessel and lymphatic ligation. The aim of this prospective RCT was to assess w…
View article: Neoadjuvant trastuzumab deruxtecan (T-DXd) with response-directed definitive therapy in early stage HER2-positive breast cancer: a phase II study protocol (SHAMROCK study)
Neoadjuvant trastuzumab deruxtecan (T-DXd) with response-directed definitive therapy in early stage HER2-positive breast cancer: a phase II study protocol (SHAMROCK study) Open
Background The current standard of care in the neoadjuvant setting for high-risk HER2-positive (HER2 +) breast cancer is to combine systemic chemotherapy with dual HER2 blockade, trastuzumab and pertuzumab. Targeted therapies have signific…
View article: Nodal positivity in patients with clinically and radiologically node-negative breast cancer treated with neoadjuvant chemotherapy: multicentre collaborative study
Nodal positivity in patients with clinically and radiologically node-negative breast cancer treated with neoadjuvant chemotherapy: multicentre collaborative study Open
Background The necessity of performing a sentinel lymph node biopsy in patients with clinically and radiologically node-negative breast cancer after neoadjuvant chemotherapy has been questioned. The aim of this study was to determine the r…
View article: Predictive modelling of response to neoadjuvant therapy in HER2+ breast cancer
Predictive modelling of response to neoadjuvant therapy in HER2+ breast cancer Open
HER2-positive (HER2+) breast cancer accounts for 20–25% of all breast cancers. Predictive biomarkers of neoadjuvant therapy response are needed to better identify patients with early stage disease who may benefit from tailored treatments i…
View article: Assessing Mode of Recurrence in Breast Cancer to Identify an Optimised Follow-Up Pathway: 10-Year Institutional Review
Assessing Mode of Recurrence in Breast Cancer to Identify an Optimised Follow-Up Pathway: 10-Year Institutional Review Open
Background Breast cancer surveillance programmes ensure early identification of recurrence which maximises overall survival. Programmes include annual clinical examination and radiological assessment. There remains debate around the value …
View article: O078 Is there a role for SLNB in women with breast cancer &gt;70 years old? A retrospective institutional review
O078 Is there a role for SLNB in women with breast cancer >70 years old? A retrospective institutional review Open
Introduction The Choosing Wisely guidelines were published to de-escalate surgical staging of the axilla in women >70 years of age with early invasive breast cancer. They advised against performing a sentinel lymph node biopsy (SLNB) in…
View article: O079 Randomised controlled trial of LigaSure use versus monopolar diathermy in mastectomy
O079 Randomised controlled trial of LigaSure use versus monopolar diathermy in mastectomy Open
Introduction LigaSure is an electrothermal bipolar vessel-sealing system shown to decrease blood loss and drainage volume compared to electrocautery in axillary node dissection. This prospective randomised controlled trial aimed to assess …
View article: The role of infiltrating lymphocytes in the neo-adjuvant treatment of women with HER2-positive breast cancer
The role of infiltrating lymphocytes in the neo-adjuvant treatment of women with HER2-positive breast cancer Open
Background Pre-treatment tumour-associated lymphocytes (TILs) and stromal lymphocytes (SLs) are independent predictive markers of future pathological complete response (pCR) in HER2-positive breast cancer. Whilst studies have correlated ba…
View article: Documentation of chaperone presence in breast clinic, a complete audit cycle
Documentation of chaperone presence in breast clinic, a complete audit cycle Open
Objective The General Medical Council (GMC) and Irish Medical Council (IMC) recommend the presence of a chaperone for all intimate examinations and that it should be clearly documented. The aim of this report is to assess doctors’ complian…
View article: Correction to: Patterns of prevalence and contemporary clinical management strategies in complicated acute biliary calculous disease: an ESTES ‘snapshot audit’ of practice
Correction to: Patterns of prevalence and contemporary clinical management strategies in complicated acute biliary calculous disease: an ESTES ‘snapshot audit’ of practice Open
The original version of this article unfortunately contained a mistake.
View article: Patients over 65 years with Acute Complicated Calculous Biliary Disease are Treated Differently—Results and Insights from the ESTES Snapshot Audit
Patients over 65 years with Acute Complicated Calculous Biliary Disease are Treated Differently—Results and Insights from the ESTES Snapshot Audit Open
Background Accrued comorbidities are perceived to increase operative risk. Surgeons may offer operative treatments less often to their older patients with acute complicated calculous biliary disease (ACCBD). We set out to capture ACCBD inc…
View article: AB183. SOH21AS215. A 2019 nationwide review of emergency vs. elective umbilical hernia repair Ireland: is there a role for non-operative management?
AB183. SOH21AS215. A 2019 nationwide review of emergency vs. elective umbilical hernia repair Ireland: is there a role for non-operative management? Open
Background: Asymptomatic umbilical hernias are often repaired electively, however there are no high-quality studies defining benefits of elective repair compared to watchful waiting. Low evidence studies suggest that elective repairs are s…
View article: AB191. SOH21AS243. Prevention of venous thromboembolism in breast cancer surgery: a systematic review
AB191. SOH21AS243. Prevention of venous thromboembolism in breast cancer surgery: a systematic review Open
Background: Surgical oncoplastic techniques and immediate autologous reconstruction for breast cancer are increasing. Previous studies have demonstrated significant variation amongst surgeons regarding the use of low molecular weight hepar…