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View article: Sodium Bicarbonate for Severe Metabolic Acidemia and Acute Kidney Injury
Sodium Bicarbonate for Severe Metabolic Acidemia and Acute Kidney Injury Open
Importance The effect of sodium bicarbonate infusion on outcome in patients with severe metabolic acidemia and moderate to severe acute kidney injury is unknown. Objective To determine whether sodium bicarbonate infusion is associated with…
View article: Outcomes of Critically Ill Adult Patients With Acute Encephalitis
Outcomes of Critically Ill Adult Patients With Acute Encephalitis Open
Importance Functional outcomes and long-term recovery after severe encephalitis are not well characterized. Objective To determine the incidence of functional disability or death at 3 months and to describe recovery trajectories through 1 …
View article: Immunosuppressive therapy management during sepsis in kidney transplant recipients: a prospective multicenter study
Immunosuppressive therapy management during sepsis in kidney transplant recipients: a prospective multicenter study Open
View article: Study protocol and statistical plan for the ICRAKI trial: Intermittent haemodialysis versus continuous renal replacement therapy for severe acute kidney injury in critically ill patients
Study protocol and statistical plan for the ICRAKI trial: Intermittent haemodialysis versus continuous renal replacement therapy for severe acute kidney injury in critically ill patients Open
View article: Heart rate variability as a marker of multiple organ dysfunction syndromes: a systematic review
Heart rate variability as a marker of multiple organ dysfunction syndromes: a systematic review Open
Multiple organ dysfunction syndrome (MODS) can be caused by many factors. Assessments of the severity of MODS are currently based on occasional measurements of several clinical variables (laboratory data, vital signs, etc.). The analysis o…
View article: Operator independent continuous ultrasound monitoring of diaphragm excursion predicts successful weaning from mechanical ventilation: a prospective observational study
Operator independent continuous ultrasound monitoring of diaphragm excursion predicts successful weaning from mechanical ventilation: a prospective observational study Open
Background In mechanically ventilated patients, diaphragm ultrasound can identify diaphragm weakness and predict weaning failure. We evaluated whether a novel operator-independent ultrasound-based medical device allowing continuous monitor…
View article: Low dose of morphine to relieve dyspnea in acute respiratory failure: the OpiDys double-blind randomized controlled trial
Low dose of morphine to relieve dyspnea in acute respiratory failure: the OpiDys double-blind randomized controlled trial Open
View article: Prone Positioning During Extracorporeal Membrane Oxygenation in Patients With Severe ARDS
Prone Positioning During Extracorporeal Membrane Oxygenation in Patients With Severe ARDS Open
Importance Prone positioning may improve outcomes in patients with severe acute respiratory distress syndrome (ARDS), but it is unknown whether prone positioning improves clinical outcomes among patients with ARDS who are undergoing venove…
View article: Immunoadsorption-Based HLA Desensitization in Patients Awaiting Deceased Donor Kidney Transplantation: An Interventional, Non-Randomised, Single Cohort Study
Immunoadsorption-Based HLA Desensitization in Patients Awaiting Deceased Donor Kidney Transplantation: An Interventional, Non-Randomised, Single Cohort Study Open
Whether immunoadsorption (IADS) as part of desensitization protocols could facilitate deceased donor kidney transplantation (KT) in highly sensitized (HS) patients remains to be proven. We retrospectively analyzed our IADS based desensitiz…
View article: Managing respiratory muscle weakness during weaning from invasive ventilation
Managing respiratory muscle weakness during weaning from invasive ventilation Open
Weaning is a critical stage of an intensive care unit (ICU) stay, in which the respiratory muscles play a major role. Weakness of the respiratory muscles, which is associated with significant morbidity in the ICU, is not limited to atrophy…
View article: Interventions Relieving Dyspnea in Intubated Patients Show Responsiveness of the Mechanical Ventilation–Respiratory Distress Observation Scale
Interventions Relieving Dyspnea in Intubated Patients Show Responsiveness of the Mechanical Ventilation–Respiratory Distress Observation Scale Open
Rationale: Breathing difficulties are highly stressful. In critically ill patients, they are associated with an increased risk of posttraumatic manifestations. Dyspnea, the corresponding symptom, cannot be directly assessed in nonco…
View article: Decreased breathing variability is associated with poorer outcome in mechanically ventilated patients
Decreased breathing variability is associated with poorer outcome in mechanically ventilated patients Open
Rationale Breathing is a cyclic activity that is variable by nature. Breathing variability is modified in mechanically ventilated patients. We aimed to evaluate whether decreased variability on the day of transition from assist-control ven…
View article: Severe SARS-Cov2 pneumonia in vaccinated patients: a multicenter cohort study
Severe SARS-Cov2 pneumonia in vaccinated patients: a multicenter cohort study Open
Vaccination reduces risk of infection, hospitalization, and death due to SARS-Cov2. Vaccinated patients may however experience severe SARS-Cov2 disease. The objective was to describe clinical features of vaccinated patients requiring inten…
View article: Implication respective des composantes sensorielles, émotionnelles et affectives dans le soulagement de la dyspnée chez les patients de réanimation
Implication respective des composantes sensorielles, émotionnelles et affectives dans le soulagement de la dyspnée chez les patients de réanimation Open
In intensive care, up to half of the patients under mechanical ventilation present a dyspnea, so intense that if it were a pain, it would require an immediate pharmacological treatment. Beyond the immediate suffering, dyspnea increases the…
View article: Kidney Upgrades Natriuresis But Not Glomerular Filtration Under Veno-Venous ECMO, A Retrospective Study
Kidney Upgrades Natriuresis But Not Glomerular Filtration Under Veno-Venous ECMO, A Retrospective Study Open
View article: Accuracy of clinicians’ ability to predict the need for renal replacement therapy: a prospective multicenter study
Accuracy of clinicians’ ability to predict the need for renal replacement therapy: a prospective multicenter study Open
View article: Low dose of morphine to relieve dyspnea in acute respiratory failure (OpiDys): protocol for a double-blind randomized controlled study
Low dose of morphine to relieve dyspnea in acute respiratory failure (OpiDys): protocol for a double-blind randomized controlled study Open
View article: Effect of High-Flow Nasal Cannula Oxygen vs Standard Oxygen Therapy on Mortality in Patients With Respiratory Failure Due to COVID-19
Effect of High-Flow Nasal Cannula Oxygen vs Standard Oxygen Therapy on Mortality in Patients With Respiratory Failure Due to COVID-19 Open
Importance The benefit of high-flow nasal cannula oxygen (high-flow oxygen) in terms of intubation and mortality in patients with respiratory failure due to COVID-19 is controversial. Objective To determine whether the use of high-flow oxy…
View article: Dyspnea and the electromyographic activity of inspiratory muscles during weaning from mechanical ventilation
Dyspnea and the electromyographic activity of inspiratory muscles during weaning from mechanical ventilation Open
Rationale Dyspnea, a key symptom of acute respiratory failure, is not among the criteria for spontaneous breathing trial (SBT) failure. Here, we sought (1) to determine whether dyspnea is a reliable failure criterion for SBT failure; (2) t…
View article: Nicotine patches in patients on mechanical ventilation for severe COVID-19: a randomized, double-blind, placebo-controlled, multicentre trial
Nicotine patches in patients on mechanical ventilation for severe COVID-19: a randomized, double-blind, placebo-controlled, multicentre trial Open
View article: Proportional assist ventilation relieves clinically significant dyspnea in critically ill ventilated patients
Proportional assist ventilation relieves clinically significant dyspnea in critically ill ventilated patients Open
Introduction Dyspnea is common and often severe symptom in mechanically ventilated patients. Proportional assist ventilation (PAV) is an assist ventilatory mode that adjusts the level of assistance to the activity of respiratory muscles. W…
View article: Safety of Inulin and Sinistrin: Combining Several Sources for Pharmacovigilance Purposes
Safety of Inulin and Sinistrin: Combining Several Sources for Pharmacovigilance Purposes Open
Introduction: Inulin and its analog sinistrin are fructose polymers used in the food and pharmaceutical industries. In 2018, The French National Agency for the Safety of Medicines and Health Products (ANSM) decided to withdraw products con…
View article: Weaning from mechanical ventilation in neurocritical care
Weaning from mechanical ventilation in neurocritical care Open
View article: L’atteinte de structures neurologiques centrales explique-elle le défaut de perception des sensations respiratoires constaté au cours de l’infection à SARS CoV 2 ?
L’atteinte de structures neurologiques centrales explique-elle le défaut de perception des sensations respiratoires constaté au cours de l’infection à SARS CoV 2 ? Open
View article: Prediction of Successful Weaning from Mechanical Ventilation by Continuous Ultrasound Monitoring of Diaphragm Excursion
Prediction of Successful Weaning from Mechanical Ventilation by Continuous Ultrasound Monitoring of Diaphragm Excursion Open
View article: Comparison of hydroxychloroquine, lopinavir/ritonavir, and standard of care in critically ill patients with SARS-CoV-2 pneumonia: an opportunistic retrospective analysis
Comparison of hydroxychloroquine, lopinavir/ritonavir, and standard of care in critically ill patients with SARS-CoV-2 pneumonia: an opportunistic retrospective analysis Open
View article: National survey of invasive procedural training for nephrology fellows and residents in France: from bedside mentoring to simulation-based teaching
National survey of invasive procedural training for nephrology fellows and residents in France: from bedside mentoring to simulation-based teaching Open
International audience
View article: Feasibility and Validity of an Observational Scale as a Surrogate of Dyspnea in Non-Communicating Intubated Patients in the Intensive Care Unit: The Mechanical Ventilation - Respiratory Distress Observation Scale
Feasibility and Validity of an Observational Scale as a Surrogate of Dyspnea in Non-Communicating Intubated Patients in the Intensive Care Unit: The Mechanical Ventilation - Respiratory Distress Observation Scale Open
View article: Pratique de la e-santé en néphrologie en France : Résultats de la première enquête sur la télénéphrologie
Pratique de la e-santé en néphrologie en France : Résultats de la première enquête sur la télénéphrologie Open
The number of new patients with chronic kidney diseases strongly increases while the one of nephrologists does not: this is developing new challenges, in which e-health will take a special part. This field is poorly investigated: so, we de…
View article: Domicile : où sont les freins ? enquête auprès des néphrologues Français
Domicile : où sont les freins ? enquête auprès des néphrologues Français Open
La dialyse à domicile, représentée par l’hémodialyse et la dialyse péritonéale, peut apporter de nombreux bénéfices aux patients atteints d’insuffisance rénale chronique terminale, particulièrement en termes de confort, de qualité de vie e…