Congqing Jiang
YOU?
Author Swipe
View article: Clinicopathological features and prognosis of patients with colorectal mucous adenocarcinoma mixed with other pathological components: A nationwide retrospective study in China
Clinicopathological features and prognosis of patients with colorectal mucous adenocarcinoma mixed with other pathological components: A nationwide retrospective study in China Open
Background. Numerous studies have examined the clinicopathological and prognostic differences between conventional adenocarcinoma and mucinous adenocarcinoma (MAC) or adenocarcinoma mixed with other pathological components. However, the fe…
View article: Staged Turnbull-Cutait pull-through anastomosis comparing with direct anastomosis plus prophylactic ileostomy in the treatment of low rectal cancer after internal sphincter resection (STAR-TAR): study protocol for a randomized controlled trial
Staged Turnbull-Cutait pull-through anastomosis comparing with direct anastomosis plus prophylactic ileostomy in the treatment of low rectal cancer after internal sphincter resection (STAR-TAR): study protocol for a randomized controlled trial Open
ClinicalTrials.gov NCT06662643. Registered on October 29, 2024.
View article: Staged Turnbull-Cutait Pull-through Anastomosis Comparing With Direct Anastomosis Plus Prophylactic Ileostomy in the Treatment of Low Rectal Cancer After Internal Sphincter Resection (STAR-TAR):study protocol for a randomized controlled trial
Staged Turnbull-Cutait Pull-through Anastomosis Comparing With Direct Anastomosis Plus Prophylactic Ileostomy in the Treatment of Low Rectal Cancer After Internal Sphincter Resection (STAR-TAR):study protocol for a randomized controlled trial Open
Background Recent advancements in the understanding of lower rectum anatomy, rectal cancer biology, and surgical techniques have emphasized the importance of radical surgery for low rectal cancer that balances oncological safety and anal f…
View article: The Effects of Intersphincteric Space Dissection Approaches on Low Rectal Cancer Outcomes: A Multicenter Retrospective Study in China
The Effects of Intersphincteric Space Dissection Approaches on Low Rectal Cancer Outcomes: A Multicenter Retrospective Study in China Open
Objective: To evaluate the effects of 2 intersphincteric space (ISS) dissection approaches for intersphincteric resection (ISR) on perioperative safety, oncological prognosis, and anal function. Background: The dissection of ISS is a cruci…
View article: Quantitative proteomics analysis reveals the pathogenesis of obstructed defecation syndrome caused by abnormal expression of dystrophin
Quantitative proteomics analysis reveals the pathogenesis of obstructed defecation syndrome caused by abnormal expression of dystrophin Open
BACKGROUND Obstructed defecation syndrome (ODS) represents the most prevalent form of chronic constipation, affecting a diverse patient population, leading to numerous complications, and imposing a significant burden on healthcare resource…
View article: Spastic pelvic floor syndrome and puborectalis syndrome: The different stages of the same disease
Spastic pelvic floor syndrome and puborectalis syndrome: The different stages of the same disease Open
The diagnosis and treatment of puborectalis syndrome (PRS) and spastic pelvic floor syndrome (SPFS) are still up for debate. This study aims to investigate examine the similarities and differences between PRS and SPFS. This study recruited…
View article: Metabolic Recoding of NSUN2‐Mediated m<sup>5</sup>C Modification Promotes the Progression of Colorectal Cancer via the NSUN2/YBX1/m<sup>5</sup>C‐ENO1 Positive Feedback Loop
Metabolic Recoding of NSUN2‐Mediated m<sup>5</sup>C Modification Promotes the Progression of Colorectal Cancer via the NSUN2/YBX1/m<sup>5</sup>C‐ENO1 Positive Feedback Loop Open
The RNA modification, 5‐methylcytosine (m 5 C), has recently gained prominence as a pivotal post‐transcriptional regulator of gene expression, intricately intertwined with various tumorigenic processes. However, the exact mechanisms govern…
View article: CRISPR/Cas9 screening: unraveling cancer immunotherapy’s ‘Rosetta Stone’
CRISPR/Cas9 screening: unraveling cancer immunotherapy’s ‘Rosetta Stone’ Open
Clustered regularly interspaced palindromic repeats (CRISPR)-based technology, a powerful toolset for the unbiased functional genomic screening of biological processes, has facilitated several scientific breakthroughs in the biomedical fie…
View article: Local Excision Versus Radical Resection for Grade 2 Rectal Neuroendocrine Tumors: A Multicenter Propensity Score-Matched Analysis
Local Excision Versus Radical Resection for Grade 2 Rectal Neuroendocrine Tumors: A Multicenter Propensity Score-Matched Analysis Open
BACKGROUND: Studies on grade 2 rectal neuroendocrine tumors are limited, and the optimal treatment for these tumors is not well established. OBJECTIVE: We aimed to compare the oncologic results of local excision versus radical resection fo…
View article: Establishing Pelvimetry-Based Machine Learning Models to Predict Surgical Difficulty in Laparoscopic Intersphincteric Resection in Patients With Low Rectal Cancer
Establishing Pelvimetry-Based Machine Learning Models to Predict Surgical Difficulty in Laparoscopic Intersphincteric Resection in Patients With Low Rectal Cancer Open
Aim Intersphincteric resection (ISR) is an anus-preserving procedure for the treatment of low rectal cancer. However, some patients have difficult ISR procedures due to pelvic stenosis. We aim to build a machine learning (ML) model to pred…
View article: Integrated analysis of the gut microbiome and metabolome in a mouse model of inflammation-induced colorectal tumors
Integrated analysis of the gut microbiome and metabolome in a mouse model of inflammation-induced colorectal tumors Open
Colorectal cancer (CRC) is a common malignancy worldwide, and the gut microbiota and metabolites play an important role in its initiation and progression. In this study, we constructed a mouse model of inflammation-induced colorectal tumor…
View article: m5C regulator-mediated modification patterns and tumor microenvironment infiltration characterization in colorectal cancer: One step closer to precision medicine
m5C regulator-mediated modification patterns and tumor microenvironment infiltration characterization in colorectal cancer: One step closer to precision medicine Open
Background The RNA modification 5-methylcytosine (m5C) is one of the most prevalent post-transcriptional modifications, with increasing evidence demonstrating its extensive involvement in the tumorigenesis and progression of various cancer…
View article: Correction to: N6-methyladenosine modification of circ_0003215 suppresses the pentose phosphate pathway and malignancy of colorectal cancer through the miR-663b/DLG4/G6PD axis
Correction to: N6-methyladenosine modification of circ_0003215 suppresses the pentose phosphate pathway and malignancy of colorectal cancer through the miR-663b/DLG4/G6PD axis Open
protein" had to be changed to "The decreased level of circ_ 0003215 was resulted from the RNA degradation by the m6A reader protein YTHDF2".
View article: N6-methyladenosine modification of circ_0003215 suppresses the pentose phosphate pathway and malignancy of colorectal cancer through the miR-663b/DLG4/G6PD axis
N6-methyladenosine modification of circ_0003215 suppresses the pentose phosphate pathway and malignancy of colorectal cancer through the miR-663b/DLG4/G6PD axis Open
Circular RNAs (circRNAs) are a recently discovered kind of regulatory RNAs that have emerged as critical biomarkers of various types of cancers. Metabolic reprogramming has gradually been identified as a distinct hallmark of cancer cells. …
View article: Ultrasensitive tumour‐agnostic non‐invasive detection of colorectal cancer recurrence using ctDNA methylation
Ultrasensitive tumour‐agnostic non‐invasive detection of colorectal cancer recurrence using ctDNA methylation Open
Dear Editor, Colorectal cancer (CRC) is the third most common cancer (10.0%) and the second leading cause of cancer-related deaths (9.4%) worldwide.1 Here we show cancer-derived DNA methylation (DNAm) enables sensitive and specific non-inv…
View article: Characterization of Circular RNA Expression Profiles in Colon Specimens of Patients with Slow Transit Constipation
Characterization of Circular RNA Expression Profiles in Colon Specimens of Patients with Slow Transit Constipation Open
Background. Slow transit constipation (STC) is a clinical syndrome characterized by a decreased urge to defecate and delayed colonic transit. Circular RNAs (circRNAs) are a recently discovered class of regulatory RNAs that have emerged as …
View article: SCG2 is a Prognostic Biomarker Associated With Immune Infiltration and Macrophage Polarization in Colorectal Cancer
SCG2 is a Prognostic Biomarker Associated With Immune Infiltration and Macrophage Polarization in Colorectal Cancer Open
Colorectal cancer (CRC) is the second most lethal malignancy around the world. Limited efficacy of immunotherapy creates an urgent need for development of novel treatment targets. Secretogranin II (SCG2) is a member of the chromogranin fam…
View article: [Retracted] MicroRNA-133a suppresses colorectal cancer cell invasion by targeting Fascin1
[Retracted] MicroRNA-133a suppresses colorectal cancer cell invasion by targeting Fascin1 Open
Following the publication of this paper, it was drawn to the Editors’ attention by a concerned reader that certain of the Transwell cell migration data shown in Fig. 4 were strikingly similar to data appearing in different form in other ar…
View article: miR-128 participates in the pathogenesis of chronic constipation by regulating the p38α/M-CSF inflammatory signaling pathway
miR-128 participates in the pathogenesis of chronic constipation by regulating the p38α/M-CSF inflammatory signaling pathway Open
Supplementary Table 1. PCR PrimerSupplementary Table 2. Antibody Information
View article: miR-128 participates in the pathogenesis of slow transit constipation by regulating the p38α/M-CSF inflammatory signaling pathway
miR-128 participates in the pathogenesis of slow transit constipation by regulating the p38α/M-CSF inflammatory signaling pathway Open
Supplementary Table 1. PCR PrimerSupplementary Table 2. Antibody Information