Congxiao Zhang
YOU?
Author Swipe
View article: Luspatercept in patients with hematological diseases who have delayed erythroid recovery after allogeneic hematopoietic stem cell transplantation.
Luspatercept in patients with hematological diseases who have delayed erythroid recovery after allogeneic hematopoietic stem cell transplantation. Open
Introduction Delayed erythroid recovery after hematopoietic stem cell transplantation (HSCT) is a common and concerning complication. The current treatment is erythropoietin, but it is effective only in some patients; other therapies, such…
View article: Advances in physical and chemical strategies for dentin hypersensitivity therapy
Advances in physical and chemical strategies for dentin hypersensitivity therapy Open
This review highlights recent advancements and ongoing challenges in applying physical and chemical strategies for DH therapy. It also discusses potential future strategies and methods, offering insights into the prospects for the field.
View article: Salvage treatment of steroid-refractory acute GVHD with the off-the-shelf product of human umbilical cord mesenchymal stromal cells: a multicenter, open label, phase Ib/IIa trial
Salvage treatment of steroid-refractory acute GVHD with the off-the-shelf product of human umbilical cord mesenchymal stromal cells: a multicenter, open label, phase Ib/IIa trial Open
View article: Prognostic effect of body mass index in patients with acute leukemia undergoing allogeneic hematopoietic stem cell transplantation: A retrospective cohort study
Prognostic effect of body mass index in patients with acute leukemia undergoing allogeneic hematopoietic stem cell transplantation: A retrospective cohort study Open
Obesity is a well-known risk factor for many diseases, but the impact of baseline body mass index (BMI) on the outcomes of allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains controversial. To elucidate the influence of …
View article: Repositioning Fluoxetine as a TRPV3 Channel Inhibitor to Alleviate Skin Inflammation and Pruritus
Repositioning Fluoxetine as a TRPV3 Channel Inhibitor to Alleviate Skin Inflammation and Pruritus Open
Transient receptor potential vanilloid 3 (TRPV3) is a non-selective cation channel prominently present in the skin. It plays a role in diverse physiological and pathological functions like inflammation of the skin, pain sensations in the s…
View article: Photothermal Effect and Biomineralization of Black Phosphorus Nanosheet‐Composited Hydrogel Boosts Synergistic Treatment of Dentin Hypersensitivity (Adv. Sci. 9/2025)
Photothermal Effect and Biomineralization of Black Phosphorus Nanosheet‐Composited Hydrogel Boosts Synergistic Treatment of Dentin Hypersensitivity (Adv. Sci. 9/2025) Open
Dentin‐Desensitized Hydrogel In article number 2412561, Congxiao Zhang, Jianxun Ding, and colleagues introduce an innovative black phosphorus nanosheet‐composited methacrylate gelatin hydrogel for treating dentin hypersensitivity. This hyd…
View article: Blinatumomab added to conditioning regimen of allogeneic hematopoietic stem cell transplantation for adult MRD <i>-</i> positive acute lymphoblastic leukemia: a single-center case series
Blinatumomab added to conditioning regimen of allogeneic hematopoietic stem cell transplantation for adult MRD <i>-</i> positive acute lymphoblastic leukemia: a single-center case series Open
Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) remains the mainstay of treatment for adults with high-risk acute lymphoblastic leukemia (ALL). Due to the crucial role of measurable residual disease (MRD) before Allo-HSCT in…
View article: Photothermal Effect and Biomineralization of Black Phosphorus Nanosheet‐Composited Hydrogel Boosts Synergistic Treatment of Dentin Hypersensitivity
Photothermal Effect and Biomineralization of Black Phosphorus Nanosheet‐Composited Hydrogel Boosts Synergistic Treatment of Dentin Hypersensitivity Open
Dentin hypersensitivity (DH), marked by exposed dentinal tubules, presents as a sharp toothache triggered by stimuli and subsides when the stimuli are removed. To address the limitations of current commercial desensitizers in terms of acid…
View article: Impact of clinical characteristics and genetic profiles on outcomes of allogeneic stem cell transplantation with sorafenib maintenance in FLT3-ITD AML patients: A multi-center, retrospective study
Impact of clinical characteristics and genetic profiles on outcomes of allogeneic stem cell transplantation with sorafenib maintenance in FLT3-ITD AML patients: A multi-center, retrospective study Open
Patients with myelodysplasia-related gene mutations (MRmut) and/or DNMT3A mutations experienced inferior outcomes after transplantation, requiring further exploration. Furthermore, similar prognoses among CR patients highligh…
View article: Chromatin Topological Domains Associate With the Rapid Formation of Tandem Duplicates in Plants
Chromatin Topological Domains Associate With the Rapid Formation of Tandem Duplicates in Plants Open
In eukaryotes, chromatin is compacted within nuclei under the principle of compartmentalization. On top of that, condensin II establishes eukaryotic chromosome territories, while cohesin organizes the vertebrate genome by extruding chromat…
View article: Risk stratification in the clinical application of minimal residual disease assessment in acute myeloid leukemia
Risk stratification in the clinical application of minimal residual disease assessment in acute myeloid leukemia Open
Background In acute myeloid leukemia (AML), further investigation is warranted to integrate measurable residual disease (MRD) with genetic characteristics for formulating a dynamic prognostic system for predicting response and selecting ap…
View article: <scp>LONP1</scp> alleviates ageing‐related renal fibrosis by maintaining mitochondrial homeostasis
<span>LONP1</span> alleviates ageing‐related renal fibrosis by maintaining mitochondrial homeostasis Open
Mitochondrial dysfunction is a pivotal event contributing to the development of ageing‐related kidney disorders. Lon protease 1 (LONP1) has been reported to be responsible for ageing‐related renal fibrosis; however, the underlying mechanis…
View article: Hyperosmotic cold shock mouse melanoma cells encapsulated with doxorubicin for targeted treatment of melanoma
Hyperosmotic cold shock mouse melanoma cells encapsulated with doxorubicin for targeted treatment of melanoma Open
Background The primary treatment strategies for melanoma include surgical excision, chemotherapy, and radiotherapy. However, the efficacy of these treatments is often limited by drug resistance, recurrence, and severe side effects. Therefo…
View article: Genome-Wide Identification and Expression Analysis of Kiwifruit Leucine-Rich Repeat Receptor-Like Proteins Reveal Their Roles in Biotic and Abiotic Stress Responses
Genome-Wide Identification and Expression Analysis of Kiwifruit Leucine-Rich Repeat Receptor-Like Proteins Reveal Their Roles in Biotic and Abiotic Stress Responses Open
Leucine-rich repeat receptor-like proteins (LRR-RLPs), a major group of receptor-like proteins in plants, have diverse functions in plant physiology, including growth, development, signal transduction, and stress responses. Despite their i…
View article: Comprehensive Analysis of Leucine-rich Repeat Receptor-like Pro-teins Provides Insights into Their Roles in Biotic and Abiotic Stress Responses in Kiwifruit
Comprehensive Analysis of Leucine-rich Repeat Receptor-like Pro-teins Provides Insights into Their Roles in Biotic and Abiotic Stress Responses in Kiwifruit Open
Kiwifruit, a perennial horticultural crop known for its nutritional value, faces significant challenges due to biotic and abiotic stresses, affecting its yield and quality. Leucine-rich repeat receptor-like proteins (LRR-RLPs), a major gro…
View article: Senolytic combination of dasatinib and quercetin protects against diabetic kidney disease by activating autophagy to alleviate podocyte dedifferentiation via the Notch pathway
Senolytic combination of dasatinib and quercetin protects against diabetic kidney disease by activating autophagy to alleviate podocyte dedifferentiation via the Notch pathway Open
The senolytics dasatinib and quercetin (DQ) alleviate age‑related disorders. However, limited information is available regarding the effects of DQ on diabetic kidney disease (DKD). The present study aimed to explore the effects of DQ on DK…
View article: Microstructure, Friction and Wear Behavior and Corrosion Resistance of electroless Double-Layer Ni-P/Ni-Mo-P Coatings on AZ91D Magnesium Alloy
Microstructure, Friction and Wear Behavior and Corrosion Resistance of electroless Double-Layer Ni-P/Ni-Mo-P Coatings on AZ91D Magnesium Alloy Open
Double-layer Ni-P coatings with low phosphorus content in the inner layer and high phosphorus content in the outer layer and Ni-Mo-P composite coatings are successfully prepared on the surface of AZ91D magnesium alloy by chemical plating p…
View article: Selective inhibition of overactive warmth-sensitive Ca2+-permeable TRPV3 channels by antispasmodic agent flopropione for alleviation of skin inflammation
Selective inhibition of overactive warmth-sensitive Ca2+-permeable TRPV3 channels by antispasmodic agent flopropione for alleviation of skin inflammation Open
The temperature-sensitive Ca2+-permeable TRPV3 ion channel is robustly expressed in the skin keratinocytes, and its gain-of-function mutations are involved in the pathology of skin lesions. Here, we report the identification of …
View article: Discovery of flavone-derivatives as the new skeleton of transient receptor potential vanilloid 3 channel antagonists
Discovery of flavone-derivatives as the new skeleton of transient receptor potential vanilloid 3 channel antagonists Open
View article: Effect of additives on the microstructure and properties of electrolytic copper foils
Effect of additives on the microstructure and properties of electrolytic copper foils Open
A low-roughness ultra-thin copper foil was prepared by pulsed electrodeposition on titanium substrate. The influence of sodium 3,3'-dithiodipropane sulfonate (SPS), hydroxyethyl cellulose (HEC), gelatin and collagen additives on the micros…
View article: Discovery of Flavone-Derivatives as the New Skeleton of Transient Receptor Potential Vanilloid 3 Channel Antagonists
Discovery of Flavone-Derivatives as the New Skeleton of Transient Receptor Potential Vanilloid 3 Channel Antagonists Open
View article: Transcriptional mapping of the macaque retina and RPE-choroid reveals conserved inter-tissue transcription drivers and signaling pathways
Transcriptional mapping of the macaque retina and RPE-choroid reveals conserved inter-tissue transcription drivers and signaling pathways Open
The macula and fovea comprise a highly sensitive visual detection tissue that is susceptible to common disease processes like age-related macular degeneration (AMD). Our understanding of the molecular determinants of high acuity vision rem…
View article: Decompression Load Analysis in Large Passenger Planes with Windshield Cracked
Decompression Load Analysis in Large Passenger Planes with Windshield Cracked Open
To prevent the possible accident of a large passenger plane due to rapid decompression, transient load analysis is of vital importance in the assessment of structure strength and also an important clause of airworthiness standard. A 0-D is…
View article: B16 Membrane-Coated Vesicles for Combined Photodynamic Therapy and Immunotherapy Shift Immune Microenvironment of Melanoma
B16 Membrane-Coated Vesicles for Combined Photodynamic Therapy and Immunotherapy Shift Immune Microenvironment of Melanoma Open
Yuqian Wang,1,* Zhilong Zhao,2,* Chenlu Liu,3 Miao Hao,1 Chenfei Kong,1 Xiaoming Zhao,1 Yiyao Gao,1 Yucheng Zhang,1 Wanxing Cui,4 Congxiao Zhang,2 Jinlan Jiang1 1Scientific Research Center, China-Japan Union Hospital, Jilin University, Cha…
View article: Transcriptional mapping of the macaque retina and RPE-choroid reveals conserved inter-tissue transcription drivers and signaling pathways
Transcriptional mapping of the macaque retina and RPE-choroid reveals conserved inter-tissue transcription drivers and signaling pathways Open
Purpose The macula and fovea comprise a highly sensitive visual detection tissue that is susceptible to common disease processes like age-related macular degeneration (AMD). Our understanding of the molecular determinants of high acuity vi…
View article: AMPK modulation ameliorates dominant disease phenotypes of CTRP5 variant in retinal degeneration
AMPK modulation ameliorates dominant disease phenotypes of CTRP5 variant in retinal degeneration Open
Late-onset retinal degeneration (L-ORD) is an autosomal dominant disorder caused by a missense substitution in CTRP5 . Distinctive clinical features include sub-retinal pigment epithelium (RPE) deposits, choroidal neovascularization, and R…
View article: Efficacy of roxadustat in treatment of peritoneal dialysis patients with renal anaemia
Efficacy of roxadustat in treatment of peritoneal dialysis patients with renal anaemia Open
The application of roxadustat in peritoneal dialysis patients with renal anaemia can effectively improve the Hb compliance rate.
View article: Interaction between CTRP5 & AdipoR1 and its implication to Late-onset retinal degeneration (L-ORD)
Interaction between CTRP5 & AdipoR1 and its implication to Late-onset retinal degeneration (L-ORD) Open
View article: Human retinal pigment epithelium secretes insulin-like growth factor 2 in vitro
Human retinal pigment epithelium secretes insulin-like growth factor 2 in vitro Open
View article: Prognostic significance of ANO1 expression in cancers
Prognostic significance of ANO1 expression in cancers Open
Background: Anoctamin-1 (ANO1) plays a pivotal role in cancer progression. A meta-analysis was conducted to assess the potential prognostic role of ANO1 in cancers. Methods: A total of 1760 patients from 7 eligible studies were included in…