Cong‐Yi Wang
YOU?
Author Swipe
View article: Ubc9‐Mediated SUMOylation of RPL3, an Unappreciated Mechanism against Hepatocyte Senescence by Repressing the DHX9‐p16 Axis
Ubc9‐Mediated SUMOylation of RPL3, an Unappreciated Mechanism against Hepatocyte Senescence by Repressing the DHX9‐p16 Axis Open
Although Ubc9‐mediated SUMOylation are recognized to regulate the multiple aspects of hepatic biological processes, its impact on hepatic senescence and metabolic dysfunction‐associated steatotic liver disease (MASLD), however, is yet to b…
View article: Exploring the bioactivity of MicroRNAs Originated from Plant-derived Exosome-like Nanoparticles (PELNs): current perspectives
Exploring the bioactivity of MicroRNAs Originated from Plant-derived Exosome-like Nanoparticles (PELNs): current perspectives Open
Exosomes, nano-sized extracellular vesicles, facilitate intercellular communication by transferring biomolecules such as microRNAs (miRNAs), which are key regulators of gene expression. While mammalian-derived exosomes (MDEs) have shown th…
View article: MBD2 promotes B cell differentiation and BCR signaling in systemic lupus erythematosus by regulating the LEF-1-PTEN-PI3K axis
MBD2 promotes B cell differentiation and BCR signaling in systemic lupus erythematosus by regulating the LEF-1-PTEN-PI3K axis Open
Systemic lupus erythematosus (SLE) is a typical autoimmune disease characterized by the overproduction of autoantibodies and type I interferon, which damages its own tissues, causing multiple organ damage. B cells are thought to play a maj…
View article: AI-Assisted Hypothesis Generation to Address Challenges in Cardiotoxicity Research: Simulation Study Using ChatGPT With GPT-4o
AI-Assisted Hypothesis Generation to Address Challenges in Cardiotoxicity Research: Simulation Study Using ChatGPT With GPT-4o Open
Background Cardiotoxicity is a major concern in heart disease research because it can lead to severe cardiac damage, including heart failure and arrhythmias. Objective This study aimed to explore the ability of ChatGPT with GPT-4o to gener…
View article: Targeting Setdb1 in T cells induces transplant tolerance without compromising antitumor immunity
Targeting Setdb1 in T cells induces transplant tolerance without compromising antitumor immunity Open
Suppressing immune responses promotes allograft survival but also favours tumour progression and recurrence. Selectively suppressing allograft rejection while maintaining or even enhancing antitumor immunity is challenging. Here, we show l…
View article: Restoration of intestinal secondary bile acid synthesis: A potential approach to improve pancreatic β cell function in type 1 diabetes
Restoration of intestinal secondary bile acid synthesis: A potential approach to improve pancreatic β cell function in type 1 diabetes Open
This study investigates the roles of gut microbiome and secondary bile acid dysfunctions in type 1 diabetes (T1D) and explores targeted interventions to address them. It finds that T1D is associated with reduced gut microbial diversity and…
View article: Broadening the Healthy Aging Paradigm: Inclusion of Gestation, Development, and Reproductive Health
Broadening the Healthy Aging Paradigm: Inclusion of Gestation, Development, and Reproductive Health Open
The prevailing focus of lifespan health research has predominantly centered on “healthy aging”. This oversight may hinder the understanding of health across the lifespan, as disorders in earlier stages can substantially impact overall heal…
View article: DDIT3 deficiency ameliorates systemic lupus erythematosus by regulating B cell activation and differentiation
DDIT3 deficiency ameliorates systemic lupus erythematosus by regulating B cell activation and differentiation Open
Systemic lupus erythematosus (SLE) is characterized by the overproduction of autoantibodies, and B cells are considered to be the primary cells involved in the development of SLE. Studies have shown that DNA damage responses play a role in…
View article: Toward accurate hand mesh estimation via masked image modeling
Toward accurate hand mesh estimation via masked image modeling Open
Introduction With an enormous number of hand images generated over time, leveraging unlabeled images for pose estimation is an emerging yet challenging topic. While some semi-supervised and self-supervised methods have emerged, they are co…
View article: Tennis expert-novice difference in motion-in-depth perception is associated with early inhibition of invalid attention
Tennis expert-novice difference in motion-in-depth perception is associated with early inhibition of invalid attention Open
Perception of motion-in-depth is essential to guide and modify the hitting action in interceptive-dominated sports (e.g., tennis). The purpose of this research was to investigate the effect of tennis expertise on motion-in-depth perception…
View article: Time-Varying Strong Coupling and Its Induced Time Diffraction of Magnon Modes
Time-Varying Strong Coupling and Its Induced Time Diffraction of Magnon Modes Open
Time-varying media break the temporal translation symmetry of wave propagation in materials, enabling advanced wave manipulations. However, this novel phenomenon has been rarely explored in magnonic systems due to the significant challenge…
View article: A Scalable Masked Image Modeling based Self-Supervised Approach for Hand Mesh Estimation
A Scalable Masked Image Modeling based Self-Supervised Approach for Hand Mesh Estimation Open
With an enormous number of hand images generated over time, unleashing pose knowledge from unlabeled images for supervised hand mesh estimation is an emerging yet challenging topic. Semi-supervised and self-supervised approaches have been …
View article: 83P Boron-doped alginate carbon-nanogel exhibits superior anti-metastatic effect on breast cancer by cell cycle arrest and actin dysfunction
83P Boron-doped alginate carbon-nanogel exhibits superior anti-metastatic effect on breast cancer by cell cycle arrest and actin dysfunction Open
Metastasis is widely recognized as the primary contributor to mortality in cancer-related cases; however, the precise mechanisms responsible for this phenomenon have yet to be fully elucidated. The potential of natural compounds, particula…
View article: Interpersonal distance perception during the normalization of an pandemic situation: Effects of mask‐wearing and vaccination
Interpersonal distance perception during the normalization of an pandemic situation: Effects of mask‐wearing and vaccination Open
This study aimed to evaluate the effect of anti‐pandemic measures, including wearing a face mask and receiving vaccinations, on interpersonal distance (IPD) during the normalization stage of the COVID‐19 pandemic. Virtual reality (VR) tech…
View article: A causal convolutional neural network for multi-subject motion modeling and generation
A causal convolutional neural network for multi-subject motion modeling and generation Open
Inspired by the success of WaveNet in multi-subject speech synthesis, we propose a novel neural network based on causal convolutions for multi-subject motion modeling and generation. The network can capture the intrinsic characteristics of…