Congyu Shi
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View article: Exploring the Impact of Fatty Acids on Ovarian Cancer Progression
Exploring the Impact of Fatty Acids on Ovarian Cancer Progression Open
Ovarian cancer (OC) stands as a formidable challenge in women's health, constituting a significant portion of gynecological-related deaths. The aggressive nature of epithelial ovarian cancer (EOC) manifests as a major hindrance to effectiv…
View article: NNMT orchestrates the proangiogenic phenotype of cancer-associated fibroblasts via epigenetically regulating ETS2 in oral squamous cell carcinoma
NNMT orchestrates the proangiogenic phenotype of cancer-associated fibroblasts via epigenetically regulating ETS2 in oral squamous cell carcinoma Open
Tumor angiogenesis is pivotal in tumorigenesis and progression. While cancer-associated fibroblasts (CAFs) are known to promote angiogenesis in oral squamous cell carcinoma (OSCC), the underlying mechanisms by which CAFs facilitate angioge…
View article: Development of fibrotic gene signature and construction of a prognostic model in melanoma
Development of fibrotic gene signature and construction of a prognostic model in melanoma Open
Purpose Skin cutaneous melanoma (SKCM) is a malignant tumor responsible for over 75% of skin cancer deaths, the relationship between fibrosis and cancer has been increasingly appreciated. The aim of this study is to investigate the fibroti…
View article: Methylation related genes are associated with prognosis of patients with head and neck squamous cell carcinoma via altering tumor immune microenvironment
Methylation related genes are associated with prognosis of patients with head and neck squamous cell carcinoma via altering tumor immune microenvironment Open
The mrDEGs can stratify HNSCC patients' prognosis, which correlates with alterations in tumor immune infiltrations and immune checkpoints.
View article: Transcriptional and H3K27ac related genome profiles in oral squamous cell carcinoma cells treated with metformin
Transcriptional and H3K27ac related genome profiles in oral squamous cell carcinoma cells treated with metformin Open
Objectives: Metformin, a first-line drug that has been used for type 2 diabetes treatment, recently attracts broad attention for its therapeutic effects on diverse human cancers. However, its effect and the underlying mechanisms on oral sq…
View article: Low expression of RalGAPs associates with the poorer overall survival of head and neck squamous cell carcinoma
Low expression of RalGAPs associates with the poorer overall survival of head and neck squamous cell carcinoma Open
RalA and RalGAPs could act as a specific predictor to assess the prognosis of HNSC. DNA methylation might be a potential mechanism that downregulated the RalGAPα2 expression.
View article: Multiple congenital granular cell tumours of the maxilla and mandible: a rare case report and review of the literature
Multiple congenital granular cell tumours of the maxilla and mandible: a rare case report and review of the literature Open
Congenital granular cell tumour (CGCT) is a benign lesion that predominantly arises from the alveolar ridges of neonates, especially the maxilla. However, it's only 10 percent of multiple lesions in all reported cases, in which simultaneou…
View article: Metformin Affects Cancer Regulation and Metabolism of Oral Squamous Cell Carcinoma Partially Through Upregulation of H3K27ac 
Metformin Affects Cancer Regulation and Metabolism of Oral Squamous Cell Carcinoma Partially Through Upregulation of H3K27ac Open
Objectives Metformin, a first-line drug that has been used for type 2 diabetes treatment, recently attracts broad attention for its therapeutic effects on diverse human cancers. However, its effect and underlying mechanisms in oral squamou…
View article: [Bioinformatics analysis of programmed cell death ligand 1 co-expression genes and their regulatory network in head and neck squamous cell carcinoma].
[Bioinformatics analysis of programmed cell death ligand 1 co-expression genes and their regulatory network in head and neck squamous cell carcinoma]. Open
PD-L1 co-expression hub genes are related to immunity, among which CCR5, CXCL9, and GZMB are prognostic markers with the possibility to be involved in programmed cell death protein 1 (PD-1)/PD-L1-induced tumor immune escape. These genes pr…