Connor Higgins
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View article: Performance of Older Adults on the Digital Clock and Recall Test Compared to the Montreal Cognitive Assessment in Primary Care Settings
Performance of Older Adults on the Digital Clock and Recall Test Compared to the Montreal Cognitive Assessment in Primary Care Settings Open
Background Digital cognitive assessment solutions can overcome some barriers to cognitive screening in primary care by providing rapidly obtained objective insights without requiring specialty trained examiners. Real-world comparison of di…
View article: Concurrent Detection of Cognitive Impairment and Amyloid Positivity with a Next-Generation Digital Cognitive Assessment
Concurrent Detection of Cognitive Impairment and Amyloid Positivity with a Next-Generation Digital Cognitive Assessment Open
Background: Early identification of cognitive impairment andbrain pathology associated with Alzheimer’s disease (AD) is essential to maximize benefits from lifestyle interventions and emerging pharmacologic disease-modifying treatments (DM…
View article: Early Identification of Alzheimer’s Disease with a Machine Learning‐Enabled Digital Cognitive Assessment: Concurrent Detection of Cognitive Impairment and Amyloid‐Beta PET Status
Early Identification of Alzheimer’s Disease with a Machine Learning‐Enabled Digital Cognitive Assessment: Concurrent Detection of Cognitive Impairment and Amyloid‐Beta PET Status Open
Background Maximizing the benefits of disease‐modifying treatments (DMTs) for Alzheimer’s disease (AD) requires early identification of cognitive impairment and abnormal brain amyloid‐beta (Aβ) status. Either one alone is insufficient. Add…
View article: Digitizing the Trails Making Test for Automatic Detection of Cognitive Impairment: Validity and Reliability
Digitizing the Trails Making Test for Automatic Detection of Cognitive Impairment: Validity and Reliability Open
Background The Trail Making Test (TMT) is one of the tests most commonly included in neuropsychological batteries to assess executive functions. A digitized version of TMT would provide objective measurements of time to complete (TTC) and …
View article: Clinical classification of memory and cognitive impairment with multimodal digital biomarkers
Clinical classification of memory and cognitive impairment with multimodal digital biomarkers Open
INTRODUCTION Early detection of Alzheimer's disease and cognitive impairment is critical to improving the healthcare trajectories of aging adults, enabling early intervention and potential prevention of decline. METHODS To evaluate multi‐m…
View article: Digital Cognitive Assessment Leveraging the Boston Process Approach Can Flag Emergent Cognitive Decline in Individuals with Subtle and Mild Functional Disability
Digital Cognitive Assessment Leveraging the Boston Process Approach Can Flag Emergent Cognitive Decline in Individuals with Subtle and Mild Functional Disability Open
Background Early detection of Mild Cognitive Impairment (MCI) and Alzheimer’s Disease and Related Dementias (ADRD) is key to optimal management. Digital tests allow for the reliable capture of meaningful, process‐based neuropsychological t…
View article: Mutational analysis of >14,000 NGS tests from community oncology practices: The Sarah Cannon molecular landscape.
Mutational analysis of >14,000 NGS tests from community oncology practices: The Sarah Cannon molecular landscape. Open
26 Background: Utilization of NGS-based testing for patients in community oncology settings continues to grow. A comprehensive analysis of the molecular landscape of > 14,000 patients with commercial tissue-based and plasma-based NGS (tbNG…