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View article: Circulating Interleukin-17A is associated with executive function in middle aged adults with and without type 2 diabetes
Circulating Interleukin-17A is associated with executive function in middle aged adults with and without type 2 diabetes Open
Midlife cardiovascular risk factors such as Type 2 Diabetes (T2DM) and obesity are associated with the later development of cognitive impairment and dementia. Systemic inflammation is postulated as a crucial mechanism, yet there are few st…
View article: Characterisation of the pro-inflammatory cytokine signature in severe COVID-19
Characterisation of the pro-inflammatory cytokine signature in severe COVID-19 Open
Clinical outcomes from infection with SARS-CoV-2, the cause of the COVID-19 pandemic, are remarkably variable ranging from asymptomatic infection to severe pneumonia and death. One of the key drivers of this variability is differing trajec…
View article: Neuropsychological decrements in midlife type-2 diabetes are not associated with peripheral NLRP3 inflammasome responsiveness
Neuropsychological decrements in midlife type-2 diabetes are not associated with peripheral NLRP3 inflammasome responsiveness Open
Midlife Type 2 Diabetes Mellitus (T2DM) is associated with an increased risk of Alzheimer Disease (AD) in later life, with altered inflammatory responses postulated as key pathological drivers. Previous studies have demonstrated increased …
View article: Kinetics of the SARS-CoV-2 Antibody Avidity Response Following Infection and Vaccination
Kinetics of the SARS-CoV-2 Antibody Avidity Response Following Infection and Vaccination Open
Serological assays capable of measuring antibody responses induced by previous infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been critical tools in the response to the COVID-19 pandemic. In this study, we…
View article: Study protocol for the St James's Hospital, Tallaght University Hospital, Trinity College Dublin Allied Researchers' (STTAR) Bioresource for COVID-19
Study protocol for the St James's Hospital, Tallaght University Hospital, Trinity College Dublin Allied Researchers' (STTAR) Bioresource for COVID-19 Open
Background: The current coronavirus disease 2019 (COVID-19) pandemic began in Ireland with the first confirmed positive case in March 2020. In the early stages of the pandemic clinicians and researchers in two affiliated Dublin hospitals i…
View article: Study Protocol for the St James's Hospital, Tallaght University Hospital, Trinity College Dublin Allied Researchers' (STTAR) Bioresource for COVID-19
Study Protocol for the St James's Hospital, Tallaght University Hospital, Trinity College Dublin Allied Researchers' (STTAR) Bioresource for COVID-19 Open
Appendices for STTAR Bioresource COVID-19 Biobanking study. The primary objective of this study is to build a biobank, to understand the clinical characteristics and natural history of COVID-19 infection with the long-term goal of research…
View article: AWARENESS AND ATTITUDE TOWARDS COVID-19 IN HYDERABAD (INDIA) METROPOLITAN CITY - AN ONLINE SURVEY.
AWARENESS AND ATTITUDE TOWARDS COVID-19 IN HYDERABAD (INDIA) METROPOLITAN CITY - AN ONLINE SURVEY. Open
Background: Corona virus disease 2019 (COVID identified in the month of December 2019 in Wuhan, China Hubei province.Since its first identification, it has spread globally.It was declared that COVID January 30, 2020 by WHO.Despite all effo…