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View article: Dictionary of human intestinal organoid responses to secreted niche factors at single cell resolution
Dictionary of human intestinal organoid responses to secreted niche factors at single cell resolution Open
The intestinal epithelium is often a site of pathology, such as in inflammatory bowel disease (IBD), and its maintenance is highly modulated by interactions with the microenvironment. However, a systematic understanding of how the myriad o…
View article: Author Correction: Multiplexed, image-based pooled screens in primary cells and tissues with PerturbView
Author Correction: Multiplexed, image-based pooled screens in primary cells and tissues with PerturbView Open
View article: SPEX: A modular end-to-end platform for high-plex tissue spatial omics analysis
SPEX: A modular end-to-end platform for high-plex tissue spatial omics analysis Open
Recent advancements in transcriptomics and proteomics have opened the possibility for spatially resolved molecular characterization of tissue architecture with the promise of enabling a deeper understanding of tissue biology in either home…
View article: Highly multiplexed, image-based pooled screens in primary cells and tissues with PerturbView
Highly multiplexed, image-based pooled screens in primary cells and tissues with PerturbView Open
Optical pooled screening (OPS) is a highly scalable method for linking image-based phenotypes with cellular perturbations. However, it has thus far been restricted to relatively low-plex phenotypic readouts in cancer cell lines in culture,…
View article: SPEX: A modular end-to-end platform for high-plex tissue spatial omics analysis
SPEX: A modular end-to-end platform for high-plex tissue spatial omics analysis Open
Recent advancements in transcriptomics and proteomics have opened the possibility for spatially resolved molecular characterization of tissue architecture with the promise of enabling a deeper understanding of tissue biology in either home…