Constanza Sommerhoff
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View article: The role of predominant polarity in older age bipolar disorder
The role of predominant polarity in older age bipolar disorder Open
PP classification distinguishes meaningful clinical and cognitive subgroups in OABD. The UPP subgroup associates with greater illness severity and functional impairment. These findings support the integration of PP into personalized treatm…
View article: Comparing cognitive reserve between patients with bipolar disorder, other psychiatric disorders and healthy controls: a systematic review and multilevel meta-analysis
Comparing cognitive reserve between patients with bipolar disorder, other psychiatric disorders and healthy controls: a systematic review and multilevel meta-analysis Open
CR is lower in BD compared to HCs, suggesting its contribution to cognitive and functional impairments. Conversely, similar CR between BD and MDD highlight shared clinical vulnerabilities. These results underscore the need for targeted int…
View article: Feasibility of Actigraphy in a Longitudinal Study of Patients with Bipolar Disorder
Feasibility of Actigraphy in a Longitudinal Study of Patients with Bipolar Disorder Open
Introduction Bipolar disorder (BD) is a severe psychiatric disorder characterized by recurring acute mood episodes of depression or euphoria, alternating with phases of euthymia, with a prevalence in the general population of 2%. Individua…
View article: Emotion dysregulation in bipolar disorder according to predominant polarity
Emotion dysregulation in bipolar disorder according to predominant polarity Open
Introduction Emotion dysregulation (ED) is a core feature of bipolar disorder (BD), impacting patients’ ability to manage intense emotional responses and maintain mood stability. Predominant polarity (PP) is a clinical specifier in BD with…
View article: Predominant Polarity for Enhanced Phenotyping and Personalized Treatment of Bipolar Disorder: A Narrative Review on Recent Findings
Predominant Polarity for Enhanced Phenotyping and Personalized Treatment of Bipolar Disorder: A Narrative Review on Recent Findings Open
Purpose of Review This paper explores Predominant Polarity (PP) in Bipolar Disorder (BD), defined as the predominance of either manic or depressive episodes over a patient’s course of illness. We examine its clinical relevance, neurobiolog…
View article: The PADRIS-PRESTO cohort: A comprehensive population-based study on mental health in Catalonia
The PADRIS-PRESTO cohort: A comprehensive population-based study on mental health in Catalonia Open
Background Mental disorders affect nearly 970 million people worldwide, impacting individuals and healthcare systems. Large population databases offer insights often unattainable in smaller studies, but their findings may not always genera…
View article: Boulevard of broken rhythms: A systematic review and meta-analysis on the relationship between sleep disturbances and suicidal behavior in bipolar disorder
Boulevard of broken rhythms: A systematic review and meta-analysis on the relationship between sleep disturbances and suicidal behavior in bipolar disorder Open
Background Among the clinical features of bipolar disorder (BD), sleep disturbances are highly prevalent and persist across all phases of the illness, from onset to acute and inter-episodic periods. Substantial evidence suggests that sleep…
View article: The relationship between sleep problems and suicidality in Bipolar Disorder: a Systematic Review and a Meta-analysis
The relationship between sleep problems and suicidality in Bipolar Disorder: a Systematic Review and a Meta-analysis Open
Introduction Bipolar disorder (BD) is a multifaceted illness encompassing mood, energy, cognitive and biorhythms alterations. Sleep disturbances are common in prodromic, acute and inter-episodic phases of BD. Suicidality presents a known a…