Corey Bunce
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View article: OoCount: A Machine-Learning Based Approach to Mouse Ovarian Follicle Counting and Classification
OoCount: A Machine-Learning Based Approach to Mouse Ovarian Follicle Counting and Classification Open
The number and distribution of ovarian follicles in each growth stage provides a reliable readout of ovarian health and function. Leveraging techniques for three-dimensional (3D) imaging of ovaries in toto has the potential to uncover tota…
View article: Adapting to Heatwaves: Reframing, Understanding, and Translating Strategies from India to the EU
Adapting to Heatwaves: Reframing, Understanding, and Translating Strategies from India to the EU Open
Policy Highlights To achieve the recommendation stated in the title, we propose the following: Adaptation should be reframed as situated, relational, and long-term processes within socio-ecological systems to maximise the value of nature-o…
View article: Biased precursor ingression underlies the center-to-pole pattern of male sex determination in mouse
Biased precursor ingression underlies the center-to-pole pattern of male sex determination in mouse Open
During mammalian development, gonadal sex determination results from the commitment of bipotential supporting cells to Sertoli or granulosa cell fates. Typically, this decision is coordinated across the gonad to ensure commitment to a sing…
View article: Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii
Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii Open
Morphogenetic events during the development of the fetal ovary are crucial to the establishment of female fertility. However, the effects of structural rearrangements of the ovary and surrounding reproductive tissues on ovary morphogenesis…
View article: Author response: Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii
Author response: Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii Open
Article Figures and data Abstract Editor's evaluation eLife digest Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract Morphogen…
View article: Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad
Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad Open
Gonadal sex determination represents a unique model for studying cell fate decisions. However, a complete understanding of the different cell lineages forming the developing testis and ovary remains elusive. Here, we investigated the origi…
View article: Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad
Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad Open
Gonadal sex determination represents a unique model for studying cell fate decisions. However, a complete understanding of the different cell lineages forming the developing testis and ovary remains elusive. Here, we investigated the origi…
View article: Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii
Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii Open
Morphogenetic events during development of the fetal ovary are crucial to the establishment of female fertility. However, the effects of structural rearrangements of the ovary and surrounding reproductive tissues on ovary morphogenesis rem…
View article: Concerted morphogenesis of genital ridges and nephric ducts in the mouse captured through whole-embryo imaging
Concerted morphogenesis of genital ridges and nephric ducts in the mouse captured through whole-embryo imaging Open
During development of the mouse urogenital complex, the gonads undergo changes in three-dimensional structure, body position and spatial relationship with the mesonephric ducts, kidneys and adrenals. The complexity of genital ridge develop…
View article: The RNA-binding protein DND1 acts sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming
The RNA-binding protein DND1 acts sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming Open
The adult spermatogonial stem cell population arises from pluripotent primordial germ cells (PGCs) that enter the fetal testis around embryonic day (E)10.5. PGCs undergo rapid mitotic proliferation, then enter prolonged cell cycle arrest (…
View article: Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development
Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development Open
Significance This study investigates the sexually dimorphic development of innervation in mouse gonads. Neural crest-derived neurons invade the dorsal surface of the mouse ovary during embryonic development and give rise to a neural networ…
View article: The RNA-Binding Protein DND<sub>1</sub>Acts Sequentially as a Negative Regulator of Pluripotency and a Positive Regulator of Epigenetic Modifiers Required for Germ Cell Reprogramming
The RNA-Binding Protein DND<sub>1</sub>Acts Sequentially as a Negative Regulator of Pluripotency and a Positive Regulator of Epigenetic Modifiers Required for Germ Cell Reprogramming Open
The adult spermatogonial stem cell population arises from pluripotent primordial germ cells (PGCs) that enter the fetal testis around embryonic day 10.5 (E10.5). These cells undergo rapid mitotic proliferation, then enter a prolonged perio…