Corinn Walker
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View article: The microbiome diversifies long- to short-chain fatty acid-derived N-acyl lipids
The microbiome diversifies long- to short-chain fatty acid-derived N-acyl lipids Open
N-Acyl lipids are important mediators of several biological processes including immune function and stress response. To enhance the detection of N-acyl lipids with untargeted mass spectrometry-based metabolomics, we created a reference spe…
View article: Trajectories of microbiome-derived bile acids in early life – insights into the progression to islet autoimmunity
Trajectories of microbiome-derived bile acids in early life – insights into the progression to islet autoimmunity Open
Recent studies reveal that gut microbes produce diverse bile acid conjugates, termed microbially conjugated bile acids (MCBAs). However, their regulation and health effects remain unclear. Here, we analyzed early-life MCBA patterns and the…
View article: The microbiome diversifies<i>N</i>-acyl lipid pools - including short-chain fatty acid-derived compounds
The microbiome diversifies<i>N</i>-acyl lipid pools - including short-chain fatty acid-derived compounds Open
N -acyl lipids are important mediators of several biological processes including immune function and stress response. To enhance the detection of N -acyl lipids with untargeted mass spectrometry-based metabolomics, we created a reference s…
View article: Empirically establishing drug exposure records directly from untargeted metabolomics data
Empirically establishing drug exposure records directly from untargeted metabolomics data Open
Despite extensive efforts, extracting information on medication exposure from clinical records remains challenging. To complement this approach, we developed the tandem mass spectrometry (MS/MS) based GNPS Drug Library. This resource integ…