Corinna Meyer
YOU?
Author Swipe
View article: NKX6-3 in B-Cell Progenitor Differentiation and Leukemia
NKX6-3 in B-Cell Progenitor Differentiation and Leukemia Open
Early B-cell development is primarily regulated at the transcriptional level and comprises the consecutive differentiation stages B-cell progenitor, pro-B-cell and pre-B-cell. These entities provide the cells of origin in B-cell precursor …
View article: Aberrant expression of MAPK1 and MCTS1 in chronic myeloid leukemia (CML)
Aberrant expression of MAPK1 and MCTS1 in chronic myeloid leukemia (CML) Open
Genomic amplification may result in aberrant gene expression and support development of cancer, including chronic myeloid leukemia (CML). In CML cell line K-562, we recently reported overexpression of TBX1 located at chromosomal position 2…
View article: Aberrant Expression and Oncogenic Activity of SPP1 in Hodgkin Lymphoma
Aberrant Expression and Oncogenic Activity of SPP1 in Hodgkin Lymphoma Open
Background: Hodgkin lymphoma (HL) is a B-cell-derived malignancy and one of the most frequent types of lymphoma. The tumour cells typically exhibit multiple genomic alterations together with aberrantly activated signalling pathways, driven…
View article: IRX-related homeobox gene MKX is a novel oncogene in acute myeloid leukemia
IRX-related homeobox gene MKX is a novel oncogene in acute myeloid leukemia Open
Homeobox genes encode transcription factors which organize differentiation processes in all tissue types including the hematopoietic compartment. Recently, we have reported physiological expression of TALE-class homeobox gene IRX1 in early…
View article: Identification of Gene Regulatory Networks in B-Cell Progenitor Differentiation and Leukemia
Identification of Gene Regulatory Networks in B-Cell Progenitor Differentiation and Leukemia Open
Pro-B- and pre-B-cells are consecutive entities in early B-cell development, representing cells of origin for B-cell precursor acute lymphoid leukemia (BCP-ALL). Normal B-cell differentiation is critically regulated by specific transcripti…
View article: Transcriptional Landscape of CUT-Class Homeobox Genes in Blastic Plasmacytoid Dendritic Cell Neoplasm
Transcriptional Landscape of CUT-Class Homeobox Genes in Blastic Plasmacytoid Dendritic Cell Neoplasm Open
Homeobox genes encode developmental transcription factors regulating tissue-specific differentiation processes and drive cancerogenesis when deregulated. Dendritic cells (DCs) are myeloid immune cells occurring as two types, either convent…
View article: Establishment of the Myeloid TBX-Code Reveals Aberrant Expression of T-Box Gene TBX1 in Chronic Myeloid Leukemia
Establishment of the Myeloid TBX-Code Reveals Aberrant Expression of T-Box Gene TBX1 in Chronic Myeloid Leukemia Open
T-box genes encode transcription factors, which control developmental processes and promote cancer if deregulated. Recently, we described the lymphoid TBX-code, which collates T-box gene activities in normal lymphopoiesis, enabling identif…
View article: Establishment of the lymphoid ETS-code reveals deregulated ETS genes in Hodgkin lymphoma
Establishment of the lymphoid ETS-code reveals deregulated ETS genes in Hodgkin lymphoma Open
The human family of ETS transcription factors numbers 28 genes which control multiple aspects of development, notably the differentiation of blood and immune cells. Otherwise, aberrant expression of ETS genes is reportedly involved in form…
View article: Chromosomal Aberration t(14;17)(q32;q21) Simultaneously Activates HOXB5 and miR10a in Triple-Hit B-Cell Lymphoma
Chromosomal Aberration t(14;17)(q32;q21) Simultaneously Activates HOXB5 and miR10a in Triple-Hit B-Cell Lymphoma Open
BCL2, BCL6 and MYC are major oncogenes in B-cell lymphoma. Their aberrant activation frequently occurs via chromosomal translocations which juxtapose light or heavy chain immunoglobulin (IG) genes to BCL2 and MYC or fuse diverse partner ge…
View article: Supplementary Table 2 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Table 2 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Table 2 from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Supplementary Figure 1C from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Figure 1C from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Figure 1C from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Supplementary Table 2 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Table 2 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Table 2 from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Supplementary Figure 2 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Figure 2 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Figure 2 from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Supplementary Figure 1D from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Figure 1D from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Figure 1D from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Supplementary Figure 1B from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Figure 1B from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Figure 1B from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Supplementary Table 1 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Table 1 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Table 1 from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Supplementary Figure 1A from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Figure 1A from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Figure 1A from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Supplementary Figure 1B from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Figure 1B from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Figure 1B from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Supplementary Table 3 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Table 3 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Table 3 from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Supplementary Figure 1D from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Figure 1D from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Figure 1D from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Supplementary Figure 1A from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Figure 1A from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Figure 1A from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Data from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Data from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
In T-cell acute lymphoblastic leukemia, alternative t(5;14)(q35;q32.2) forms effect dysregulation of either TLX3 or NKX2-5 homeobox genes at 5q35 by juxtaposition with 14q32.2 breakpoints dispersed across the BCL11B downstream genomic dese…
View article: Data from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Data from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
In T-cell acute lymphoblastic leukemia, alternative t(5;14)(q35;q32.2) forms effect dysregulation of either TLX3 or NKX2-5 homeobox genes at 5q35 by juxtaposition with 14q32.2 breakpoints dispersed across the BCL11B downstream genomic dese…
View article: Supplementary Table 3 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Table 3 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Table 3 from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Supplementary Table 1 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Table 1 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Table 1 from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Supplementary Figure 2 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Figure 2 from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Figure 2 from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Supplementary Figure 1C from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1
Supplementary Figure 1C from Activation of <i>TLX3</i> and <i>NKX2-5</i> in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-<i>BCL11B</i> Enhancers and Coregulation by PU.1 and HMGA1 Open
Supplementary Figure 1C from Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-Cell Acute Lymphoblastic Leukemia by Remote 3′-BCL11B Enhancers and Coregulation by PU.1 and HMGA1
View article: Normal and Aberrant TALE-Class Homeobox Gene Activities in Pro-B-Cells and B-Cell Precursor Acute Lymphoblastic Leukemia
Normal and Aberrant TALE-Class Homeobox Gene Activities in Pro-B-Cells and B-Cell Precursor Acute Lymphoblastic Leukemia Open
Homeobox genes encode transcription factors regulating basic developmental processes. They are arranged according to sequence similarities of their conserved homeobox in 11 classes, including TALE. Recently, we have reported the so-called …
View article: Genomic Aberrations Generate Fusion Gene FOXK2::TP63 and Activate NFKB1 in Cutaneous T-Cell Lymphoma
Genomic Aberrations Generate Fusion Gene FOXK2::TP63 and Activate NFKB1 in Cutaneous T-Cell Lymphoma Open
Cutaneous T-cell lymphoma (CTCL) is a severe lymphoid malignancy with a worse prognosis lacking curative treatment regimens. Several gene mutations and deregulated pathways, including NFkB signaling, have been implicated in its pathogenesi…
View article: Downregulation of STAT3 in Epstein-Barr Virus-Positive Hodgkin Lymphoma
Downregulation of STAT3 in Epstein-Barr Virus-Positive Hodgkin Lymphoma Open
STAT3 is a transcription factor which is activated via various signaling transduction pathways or Epstein-Barr virus (EBV) infection and plays an oncogenic role in lymphoid malignancies including Hodgkin lymphoma (HL). The tumor cells of H…