Corinne De Gregorio
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View article: Abundant Yet Aberrant T Helper Cell Responses to <i>Candida albicans</i> Underlie Mucosal Candidiasis in Humans and Mice
Abundant Yet Aberrant T Helper Cell Responses to <i>Candida albicans</i> Underlie Mucosal Candidiasis in Humans and Mice Open
T helper cell subsets—Th1, Th2, and Th17—coordinate pathogen‐specific immune responses. Candida albicans ‐specific T cells include protective Th17 cells alongside other Th subsets. However, the role of alternative Th subsets remains unclea…
View article: Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses
Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses Open
Mucosal-associated invariant T (MAIT) cells use canonical semi-invariant T cell receptors (TCR) to recognize microbial riboflavin precursors displayed by the antigen-presenting molecule MR1. The extent of MAIT TCR crossreactivity toward ph…
View article: Nucleobase adduct-containing metabolites are MR1 ligands that stimulate self-reactive MR1T cells
Nucleobase adduct-containing metabolites are MR1 ligands that stimulate self-reactive MR1T cells Open
Summary MR1T lymphocytes are a recently identified population of T cells that recognize unknown self-antigens presented by the non-polymorphic MHC-I-related molecule, MR1. MR1T cells can kill tumor cells and modulate the functions of other…
View article: The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation
The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation Open
View article: Class and specificity of T cells against fungal pathogens in normal and pathological conditions
Class and specificity of T cells against fungal pathogens in normal and pathological conditions Open
View article: Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination
Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination Open
Vaccinology aims to understand what factors drive vaccine-induced immunity and protection. For many vaccines, however, the mechanisms underlying immunity and protection remain incompletely characterized at best, and except for neutralizing…