Explanipedia

Nuclear-encoded tRNA genes harbor substantial allelic diversity in three nematode species Open

Avery Davis Bell, Corinne Simonti, Hector Baños, Ling Wang, Christine Heitsch , et al. · 2025

Cytosolic transfer RNAs, which are encoded as hundreds of genes in eukaryotic nuclear genomes, experience exceptionally high rates of mutation and have been hypothesized to carry significant mutational load in natural populations. Comparis…

In Science Journals Open

Bianca Lopez, L. Bryan Ray, Brandon Berry, Jake Yeston, Jelena Stajic , et al. · 2025

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Peter Stern, Ian S. Osborne, Mattia Maroso, Melissa McCartney, Corinne Simonti , et al. · 2025

Computer science Engineering

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How much is Transcription-associated Mutagenesis Driving tRNA Microevolution? Open

Hector Baños, Ling Wang, Corinne Simonti, Annalise B. Paaby, Christine Heitsch · 2025

Biology Sociology

Transfer RNAs (tRNAs) are among the most highly conserved and frequently transcribed genes. Recent studies have identified transcription-associated mutagenesis (TAM) as a significant contributor to sequence variation around tRNA loci. Howe…

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Melisa Yashinski, Leslie K. Ferrarelli, Marc S. Lavine, Madeleine Seale, Jake Yeston , et al. · 2025

Computer science

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Leslie K. Ferrarelli, Jake Yeston, Bianca Lopez, Yury Suleymanov, Di Jiang , et al. · 2025

Computer science

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K. V. Hodges, Corinne Simonti, Jesse S. Smith, Phil Szuromi, Jake Yeston , et al. · 2025

Computer science

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Corinne Simonti, J. B. Smith, Priscilla N. Kelly, Caroline Ash, Mattia Maroso , et al. · 2025

Computer science Geology

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Corinne Simonti, Caroline Ash, Brent Grocholski, Marc S. Lavine, Bianca Lopez , et al. · 2024

Psychology

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Corinne Simonti, Brad Wible, Sacha Vignieri, Ankit Walia, Iyinoluwa Sofowora , et al. · 2024

Computer science Geology

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Jesse Smith, Iyinoluwa Sofowora, Stella M. Hurtley, Sarah H. Ross, Corinne Simonti , et al. · 2024

Computer science Engineering

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Jesse S. Smith, Marc S. Lavine, Phil Szuromi, Sacha Vignieri, Brent Grocholski , et al. · 2024

Biology Computer science

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Ankit Walia, Melissa McCartney, Bianca Lopez, Di Jiang, Yury Suleymanov , et al. · 2024

Computer science Geology

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Ankit Walia, Corinne Simonti, Mattia Maroso, Caroline Ash, Ian S. Osborne , et al. · 2024

Business

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Ankit Walia, Phil Szuromi, Jelena Stajic, Jake Yeston, Marc S. Lavine , et al. · 2024

Computer science

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Bianca Lopez, Jake Yeston, Phil Szuromi, Sacha Vignieri, Michael A. Funk , et al. · 2024

Computer science

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Phil Szuromi, Seth Thomas Scanlon, Jake Yeston, Jelena Stajic, Melissa Norton , et al. · 2024

Computer science

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Heterogeneous genetic architectures and evolutionary genomics of prostate cancer in Sub-Saharan Africa Open

Timothy R. Rebbeck, Rohini Janivara, Wenlong Carl Chen, Ujani Hazra, Shakuntala Baichoo , et al. · 2023

Biology Medicine Sociology

Men of African descent have the highest prostate cancer (CaP) incidence and mortality rates, yet the genetic basis of CaP in African men has been understudied. We used genomic data from 3,963 CaP cases and 3,509 controls recruited in Ghana…

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H. Jesse Smith, Yevgeniya Nusinovich, Ian S. Osborne, Sacha Vignieri, Di Jiang , et al. · 2023

Political science

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Bianca Lopez, Jake Yeston, Brent Grocholski, Seth Thomas Scanlon, Daniela Neuhofer , et al. · 2023

Computer science

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Maddy Seale, Priscilla N. Kelly, Brent Grocholski, Ian S. Osborne, H. Jesse Smith , et al. · 2023

Political science Computer science Engineering

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Maddy Seale, Mattia Maroso, Michael A. Funk, Caroline Ash, Jake Yeston , et al. · 2023

Computer science Geology

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Sacha Vignieri, Jake Yeston, L. Bryan Ray, Craig E. Cameron, Phil Szuromi , et al. · 2023

Computer science

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Bianca Lopez, Seth Thomas Scanlon, Mattia Maroso, Corinne Simonti, Michael A. Funk , et al. · 2023

Political science Computer science Geology

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Maddy Seale, Phil Szuromi, Mattia Maroso, Corinne Simonti, Caroline Ash , et al. · 2023

Computer science Biology

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Data from A Custom Genotyping Array Reveals Population-Level Heterogeneity for the Genetic Risks of Prostate Cancer and Other Cancers in Africa Open

Maxine Harlemon, Olabode Ajayi, Paidamoyo Kachambwa, Michelle S. Kim, Corinne Simonti , et al. · 2023

Biology Medicine

Although prostate cancer is the leading cause of cancer mortality for African men, the vast majority of known disease associations have been detected in European study cohorts. Furthermore, most genome-wide association studies have used ge…

Data from A Custom Genotyping Array Reveals Population-Level Heterogeneity for the Genetic Risks of Prostate Cancer and Other Cancers in Africa Open

Maxine Harlemon, Olabode Ajayi, Paidamoyo Kachambwa, Michelle S. Kim, Corinne Simonti , et al. · 2023

Biology Medicine

Although prostate cancer is the leading cause of cancer mortality for African men, the vast majority of known disease associations have been detected in European study cohorts. Furthermore, most genome-wide association studies have used ge…

Table S1 from A Custom Genotyping Array Reveals Population-Level Heterogeneity for the Genetic Risks of Prostate Cancer and Other Cancers in Africa Open

Maxine Harlemon, Olabode Ajayi, Paidamoyo Kachambwa, Michelle S. Kim, Corinne Simonti , et al. · 2023

Medicine Biology Computer science

Successfully called markers on the MADCaP Array. This tab-delimited file includes genomic positions, inclusion criteria, and overlap with other arrays.

Table S2 from A Custom Genotyping Array Reveals Population-Level Heterogeneity for the Genetic Risks of Prostate Cancer and Other Cancers in Africa Open

Maxine Harlemon, Olabode Ajayi, Paidamoyo Kachambwa, Michelle S. Kim, Corinne Simonti , et al. · 2023

Biology Mathematics Computer science

This .xlsx file lists Axiom genotyping solution QC thresholds. Genotyping metrics for both pegs of the MADCaP Array are listed here. This file also includes Benjamini-Hochberg adjusted p-values (FDR = 5%) for pairwise comparisons of derive…

Table S1 from A Custom Genotyping Array Reveals Population-Level Heterogeneity for the Genetic Risks of Prostate Cancer and Other Cancers in Africa Open

Maxine Harlemon, Olabode Ajayi, Paidamoyo Kachambwa, Michelle S. Kim, Corinne Simonti , et al. · 2023

Biology Medicine Computer science

Successfully called markers on the MADCaP Array. This tab-delimited file includes genomic positions, inclusion criteria, and overlap with other arrays.

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