Cornel Popovici
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View article: Inhibition of STAT3/Fanconi anemia axis by Nifuroxazide is synthetic lethal with PARP inhibitor and selectively targets breast cancer stem cells
Inhibition of STAT3/Fanconi anemia axis by Nifuroxazide is synthetic lethal with PARP inhibitor and selectively targets breast cancer stem cells Open
The targeting of cancer stem cells (CSCs) has proven to be an effective approach for limiting tumor progression, thus necessitating the identification of new drugs with anti-CSC activity. Through a high-throughput drug repositioning screen…
View article: Association and Performance of Polygenic Risk Scores for Breast Cancer Among French Women Presenting or Not a Familial Predisposition to the Disease
Association and Performance of Polygenic Risk Scores for Breast Cancer Among French Women Presenting or Not a Familial Predisposition to the Disease Open
View article: Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers
Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers Open
View article: Additional file 3 of Prospective high-throughput genome profiling of advanced cancers: results of the PERMED-01 clinical trial
Additional file 3 of Prospective high-throughput genome profiling of advanced cancers: results of the PERMED-01 clinical trial Open
Additional file 3: Supplementary Tables. Contains eight Supplementary Tables regarding gene lists, patients’ characteristics, univariate analyses, efficacy results, and pan-cancer HRD rates.
View article: Bernard–Soulier syndrome: first human case due to a homozygous deletion of GP9 gene
Bernard–Soulier syndrome: first human case due to a homozygous deletion of GP9 gene Open
The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. The Journal also features annotations, reviews, short reports, images in haematology and Letters to the Editor.
View article: Targeted NGS, array-CGH, and patient-derived tumor xenografts for precision medicine in advanced breast cancer: a single-center prospective study
Targeted NGS, array-CGH, and patient-derived tumor xenografts for precision medicine in advanced breast cancer: a single-center prospective study Open
Precision medicine can be implemented in a single center in the context of clinical practice and may allow genomic-driven treatment in approximately 30% of aBC patients. PDX may be obtained in a significant fraction of cases.