Cornelia Holler
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View article: Bottom-up investigation of spatiotemporal glycocalyx dynamics with interferometric scattering microscopy
Bottom-up investigation of spatiotemporal glycocalyx dynamics with interferometric scattering microscopy Open
Over recent decades, the glycocalyx, an extracellular organelle comprised of a multitude of glycolipids, glycoproteins, proteoglycans and glycoRNA, has gained considerable interest in cellular biology. While research in this field has reve…
View article: iSCAT microscopy and particle tracking with tailored spatial coherence
iSCAT microscopy and particle tracking with tailored spatial coherence Open
Interferometric scattering (iSCAT) microscopy has demonstrated unparalleled performance among label-free optical methods for detecting and imaging isolated nanoparticles and molecules. However, when imaging complex structures such as biolo…
View article: A paintbrush for delivery of nanoparticles and molecules to live cells with precise spatiotemporal control
A paintbrush for delivery of nanoparticles and molecules to live cells with precise spatiotemporal control Open
View article: A paintbrush for delivery of nanoparticles and small molecules to live cells with micrometer spatial and millisecond temporal control
A paintbrush for delivery of nanoparticles and small molecules to live cells with micrometer spatial and millisecond temporal control Open
Delivery of very small amounts of reagents to cells with micrometer spatial precision and millisecond time resolution is currently out of reach, but would strongly facilitate quantitative studies in cell biology. Here, we present a micropi…
View article: High-Precision Protein-Tracking With Interferometric Scattering Microscopy
High-Precision Protein-Tracking With Interferometric Scattering Microscopy Open
The mobility of proteins and lipids within the cell, sculpted oftentimes by the organization of the membrane, reveals a great wealth of information on the function and interaction of these molecules as well as the membrane itself. Single p…
View article: High-precision protein-tracking with interferometric scattering microscopy
High-precision protein-tracking with interferometric scattering microscopy Open
The mobility of proteins and lipids within the cell, sculpted oftentimes by the organisation of the membrane, reveals a great wealth of information on the function and interaction of these molecules as well as the membrane itself. Single p…
View article: Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1
Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1 Open