Cornelia Roesl
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View article: Confocal Endomicroscopy of Neuromuscular Junctions Stained with Physiologically Inert Protein Fragments of Tetanus Toxin
Confocal Endomicroscopy of Neuromuscular Junctions Stained with Physiologically Inert Protein Fragments of Tetanus Toxin Open
Live imaging of neuromuscular junctions (NMJs) in situ has been constrained by the suitability of ligands for inert vital staining of motor nerve terminals. Here, we constructed several truncated derivatives of the tetanus toxin C-fragment…
View article: A comparison of in vivo viral targeting systems identifies adeno‐associated virus serotype 9 (AAV9) as an effective vector for genetic manipulation of Leydig cells in adult mice
A comparison of in vivo viral targeting systems identifies adeno‐associated virus serotype 9 (AAV9) as an effective vector for genetic manipulation of Leydig cells in adult mice Open
Background Despite the increasing popularity of deliverable transgenics, a robust and fully validated method for targeting Leydig cells, capable of delivering long‐term transgene expression, is yet to be defined. Objectives We compared thr…
View article: Functional analysis of<i>RYR1</i>variants linked to malignant hyperthermia
Functional analysis of<i>RYR1</i>variants linked to malignant hyperthermia Open
Malignant hyperthermia manifests as a rapid and sustained rise in temperature in response to pharmacological triggering agents, e.g. inhalational anesthetics and the muscle relaxant suxamethonium. Other clinical signs include an increase i…
View article: Sertoli cell androgen receptor signalling in adulthood is essential for post-meiotic germ cell development
Sertoli cell androgen receptor signalling in adulthood is essential for post-meiotic germ cell development Open
Acknowledgements We thank Dr. Laura O’Hara and Dr. Forbes Howie for technical support.