Cosimo Cristella
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View article: Parasitic, bacterial, viral, immune-mediated, metabolic and nutritional factors associated with nodding syndrome
Parasitic, bacterial, viral, immune-mediated, metabolic and nutritional factors associated with nodding syndrome Open
Nodding syndrome is a neglected, disabling and potentially fatal epileptic disorder of unknown aetiology affecting thousands of individuals mostly confined to Eastern sub-Saharan Africa. Previous studies have identified multiple associatio…
View article: Informing epidemic (research) responses in a timely fashion by knowledge management - a Zika virus use case
Informing epidemic (research) responses in a timely fashion by knowledge management - a Zika virus use case Open
The response of pathophysiological research to emerging epidemics often occurs after the epidemic and, as a consequence, has little to no impact on improving patient outcomes or on developing high-quality evidence to inform clinical manage…
View article: Informing epidemic (research) responses in a timely fashion by knowledge management - a Zika virus use case
Informing epidemic (research) responses in a timely fashion by knowledge management - a Zika virus use case Open
The response of pathophysiological research to emerging epidemics often occurs after the epidemic and, as a consequence, has little to no impact on improving patient outcomes or on developing high-quality evidence to inform clinical manage…
View article: Polarized Entry of Human Parechoviruses in the Airway Epithelium
Polarized Entry of Human Parechoviruses in the Airway Epithelium Open
Human parechoviruses (HPeVs), a poorly studied genus within the Picornaviridae family, are classified into 19 genotypes of which HPeV1 and HPeV3 are the most often detected. HPeV1 VP1 C terminus contains an arginine-glycine-aspartic…
View article: Novel Orthobunyavirus Identified in the Cerebrospinal Fluid of a Ugandan Child With Severe Encephalopathy
Novel Orthobunyavirus Identified in the Cerebrospinal Fluid of a Ugandan Child With Severe Encephalopathy Open
A Ugandan child with an unexplained encephalitis was investigated using viral metagenomics. Several sequences from all segments of a novel orthobunyavirus were found. The S-segment, used for typing, showed 41% amino acid diversity to its c…