Craig Daniels
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View article: Targeting TET3 suppresses group 3 medulloblastoma stemness and progression via impairing hypomethylation of Otx2 super-enhancer
Targeting TET3 suppresses group 3 medulloblastoma stemness and progression via impairing hypomethylation of Otx2 super-enhancer Open
View article: Supplementary Figure 5 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy
Supplementary Figure 5 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy Open
Figure S5
View article: Supplementary Figure 7 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy
Supplementary Figure 7 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy Open
Figure S7
View article: Supplementary Figure 4 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy
Supplementary Figure 4 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy Open
Figure S4
View article: Supplementary Figure 1 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy
Supplementary Figure 1 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy Open
Figure S1
View article: Supplementary Table 3 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy
Supplementary Table 3 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy Open
Table S3
View article: Data from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy
Data from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy Open
Group 3 (G3) medulloblastoma constitutes the most aggressive molecular subgroup, and nearly all patients present with metastases upon recurrence. Treatment for newly diagnosed medulloblastoma relies on a combination of maximal safe surgica…
View article: Supplementary Table 2 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy
Supplementary Table 2 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy Open
Table S2
View article: Supplementary Figure 3 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy
Supplementary Figure 3 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy Open
Figure S3
View article: Supplementary Figure 2 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy
Supplementary Figure 2 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy Open
Figure S2
View article: Supplementary Table 1 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy
Supplementary Table 1 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy Open
Table S1
View article: Supplementary Figure 6 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy
Supplementary Figure 6 from Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiotherapy Open
Figure S6
View article: Rapid impedance-based Antimicrobial Susceptibility Testing (iFAST) of Enterobacterales in urinary tract infections
Rapid impedance-based Antimicrobial Susceptibility Testing (iFAST) of Enterobacterales in urinary tract infections Open
iFAST has potential as an accurate and rapid AST for UTI causing Enterobacterales.
View article: Metastatic medulloblastoma remodels the local leptomeningeal microenvironment to promote further metastatic colonization and growth
Metastatic medulloblastoma remodels the local leptomeningeal microenvironment to promote further metastatic colonization and growth Open
View article: High cellular plasticity state of medulloblastoma local recurrence and distant dissemination
High cellular plasticity state of medulloblastoma local recurrence and distant dissemination Open
Medulloblastoma (MB), a heterogeneous pediatric brain tumor, poses challenges in the treatment of tumor recurrence and dissemination. To characterize cellular diversity and genetic features, we comprehensively analyzed single-cell/nucleus …
View article: Risk factors for post-operative cognitive dysfunction following multilevel lumbar spinal fusion
Risk factors for post-operative cognitive dysfunction following multilevel lumbar spinal fusion Open
View article: ZIC1 is a context-dependent medulloblastoma driver in the rhombic lip
ZIC1 is a context-dependent medulloblastoma driver in the rhombic lip Open
View article: Alcohol Alters Skeletal Muscle Bioenergetic Function: A Scoping Review
Alcohol Alters Skeletal Muscle Bioenergetic Function: A Scoping Review Open
Bioenergetic pathways uniquely support sarcomere function which, in turn, helps to maintain functional skeletal muscle (SKM) mass. Emerging evidence supports alcohol (EtOH)-induced bioenergetic impairments in SKM and muscle precursor cells…
View article: Early rhombic lip Protogenin+ve stem cells in a human-specific neurovascular niche initiate and maintain group 3 medulloblastoma
Early rhombic lip Protogenin+ve stem cells in a human-specific neurovascular niche initiate and maintain group 3 medulloblastoma Open
View article: Lipidomic-Based Approach to 10 s Classification of Major Pediatric Brain Cancer Types with Picosecond Infrared Laser Mass Spectrometry
Lipidomic-Based Approach to 10 s Classification of Major Pediatric Brain Cancer Types with Picosecond Infrared Laser Mass Spectrometry Open
Picosecond infrared laser mass spectrometry (PIRL-MS) is shown, through a retrospective patient tissue study, to differentiate medulloblastoma cancers from pilocytic astrocytoma and two molecular subtypes of ependymoma (PF-EPN-A, ST-EPN-RE…
View article: Conceptualization of Remote Patient Monitoring Program for Patients with Complex Medical Illness on Hospital Dismissal
Conceptualization of Remote Patient Monitoring Program for Patients with Complex Medical Illness on Hospital Dismissal Open
RPM can uniquely facilitate the transition from hospital to home, decrease hospital length of stay, and optimize hospital capacity and staffing resources in select scenarios. To achieve positive results at the health care system level, RPM…
View article: Development and Implementation of an Acute Kidney Injury Remote Patient Monitoring Program: Research Letter
Development and Implementation of an Acute Kidney Injury Remote Patient Monitoring Program: Research Letter Open
Acute kidney injury (AKI) survivors have a dynamic posthospital course which warrants close monitoring. Remote patient monitoring (RPM) could be used to improve quality and efficiency of AKI survivor care. Objective: The objective of this …
View article: EPCO-38. TYPE B ULTRA LONG-RANGE INTERACTIONS IN PFAS (TULIPS) ARE RECURRENT EPIGENOMIC FEATURES OF PFA EPENDYMOMA
EPCO-38. TYPE B ULTRA LONG-RANGE INTERACTIONS IN PFAS (TULIPS) ARE RECURRENT EPIGENOMIC FEATURES OF PFA EPENDYMOMA Open
Posterior Fossa Group A (PFA) ependymomas are pediatric brain tumors with extremely poor survival outcomes. As protein-coding mutations in PFA are exceedingly rare, the underlying etiology of these tumors remains elusive. Elevated CpG isla…
View article: <i>In vivo</i>functional genomics identifies essentiality of potassium homeostasis in medulloblastoma
<i>In vivo</i>functional genomics identifies essentiality of potassium homeostasis in medulloblastoma Open
The identification of cancer maintenance genes—driver genes essential to tumor survival—is fundamental for developing effective cancer therapy. Transposon-based insertional mutagenesis screens can identify cancer driver genes broadly but n…
View article: Pediatric posterior fossa ependymoma and metabolism
Pediatric posterior fossa ependymoma and metabolism Open
Ependymomas are a lethal central nervous system (CNS) tumor found in both adults and children. Recent efforts have focused on risk stratification by classifying the molecular variants of CNS ependymoma. Despite this increased knowledge of …
View article: 37-Year-Old Man With an Altered Level of Consciousness
37-Year-Old Man With an Altered Level of Consciousness Open
View article: The transcriptional landscape of Shh medulloblastoma
The transcriptional landscape of Shh medulloblastoma Open
View article: Relocation and transfer of patients to a new hospital: Practical lessons
Relocation and transfer of patients to a new hospital: Practical lessons Open
Objective: We describe the practical aspects of planning for and executing the safe movement of patients and care teams from an existing tertiary hospital (Mafraq Hospital) to a new hospital (Sheikh Shakhbout Medical City) in Abu Dhabi, Un…
View article: Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma
Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma Open
View article: SPONTANEOUS BACTERIAL EMPYEMA: A DANGEROUS COMPLICATION OF HEPATIC HYDROTHORAX
SPONTANEOUS BACTERIAL EMPYEMA: A DANGEROUS COMPLICATION OF HEPATIC HYDROTHORAX Open