Craig Michell
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View article: A Genomic Framework for Climate-Resilient Conservation
A Genomic Framework for Climate-Resilient Conservation Open
Effective climate-resilient ecosystem management requires predictive tools that link genomic variation with future environmental conditions, yet, translating such forecasts into actionable conservation strategies remains a major challenge.…
View article: Chromosome-level reference genome assembly for the mountain hare (Lepus timidus)
Chromosome-level reference genome assembly for the mountain hare (Lepus timidus) Open
We present here a high-quality genome assembly of a male mountain hare ( Lepus timidus Linnaeus), from Ilomantsi, Eastern Finland, utilizing an isolated fibroblast cell line as the source for high quality DNA and RNA. Following the previou…
View article: Species differences in glycerol-3-phosphate metabolism reveals trade-offs between metabolic adaptations and cell proliferation
Species differences in glycerol-3-phosphate metabolism reveals trade-offs between metabolic adaptations and cell proliferation Open
The temperate climate-adapted brown hare (Lepus europaeus) and the cold-adapted mountain hare (Lepus timidus) are closely related and interfertile species. However, their skin fibroblasts display distinct gene expression profiles related t…
View article: Linear DNA-driven recombination in mammalian mitochondria
Linear DNA-driven recombination in mammalian mitochondria Open
Mitochondrial DNA (mtDNA) recombination in animals has remained enigmatic due to its uniparental inheritance and subsequent homoplasmic state, which excludes the biological need for genetic recombination, as well as limits tools to study i…
View article: Chromosome-level reference genome assembly for the mountain hare ( <i>Lepus timidus</i> )
Chromosome-level reference genome assembly for the mountain hare ( <i>Lepus timidus</i> ) Open
We present here a high-quality genome assembly of a male mountain hare ( Lepus timidus Linnaeus), from Ilomantsi, Eastern Finland, utilizing an isolated fibroblast cell line as the source for high quality DNA and RNA. Following the previou…
View article: A species difference in glycerol-3-phosphate metabolism reveals metabolic adaptations in hares
A species difference in glycerol-3-phosphate metabolism reveals metabolic adaptations in hares Open
The temperate climate adapted brown hare (Lepus europaeus) and the cold-adapted mountain hare (Lepus timidus) are evolutionarily closely related and interfertile. Still, their cultured skin fibroblasts show clear differences in the express…
View article: High quality genome assembly of the brown hare (Lepus europaeus) with chromosome-level scaffolding
High quality genome assembly of the brown hare (Lepus europaeus) with chromosome-level scaffolding Open
We present here a high-quality genome assembly of the brown hare ( Lepus europaeus Pallas), based on a fibroblast cell line of a male specimen from Liperi, Eastern Finland. This brown hare genome represents the first Finnish contribution t…
View article: Linear DNA-driven recombination in mammalian mitochondria
Linear DNA-driven recombination in mammalian mitochondria Open
Mitochondrial DNA (mtDNA) recombination in animals has remained enigmatic due to its uniparental inheritance and subsequent homoplasmic state, which excludes the biological need for genetic recombination, as well as limits tools to study i…
View article: Loss of species and genetic diversity during colonization: Insights from acanthocephalan parasites in northern European seals
Loss of species and genetic diversity during colonization: Insights from acanthocephalan parasites in northern European seals Open
Studies on host–parasite systems that have experienced distributional shifts, range fragmentation, and population declines in the past can provide information regarding how parasite community richness and genetic diversity will change as a…
View article: High quality genome assembly of the brown hare (Lepus europaeus) with chromosome-level scaffolding
High quality genome assembly of the brown hare (Lepus europaeus) with chromosome-level scaffolding Open
We present here a high-quality genome assembly of the brown hare (Lepus europaeus Pallas), based on a fibroblast cell line of a male specimen from Liperi, Eastern Finland. This brown hare genome represents the first Finnish contribution to…
View article: Loss of species and genetic diversity during colonization: insights from acanthocephalan parasites in northern European seals
Loss of species and genetic diversity during colonization: insights from acanthocephalan parasites in northern European seals Open
Corynosoma COI and RADseq data sets
View article: Loss of species and genetic diversity during colonization: insights from acanthocephalan parasites in northern European seals
Loss of species and genetic diversity during colonization: insights from acanthocephalan parasites in northern European seals Open
Corynosoma COI and RADseq data sets
View article: Global mesozooplankton communities show lower connectivity in deep oceanic layers
Global mesozooplankton communities show lower connectivity in deep oceanic layers Open
Mesozooplankton is a key component of the ocean, regulating global processes such as the carbon pump, and ensuring energy transfer from lower to higher trophic levels. Yet, despite the importance of understanding mesozooplankton diversity,…
View article: Mountain- and brown hare genetic polymorphisms to survey local adaptations and conservation status of the heath hare (Lepus timidus sylvaticus, Nilsson 1831)
Mountain- and brown hare genetic polymorphisms to survey local adaptations and conservation status of the heath hare (Lepus timidus sylvaticus, Nilsson 1831) Open
We provide the first whole genome sequences from three specimens of the mountain hare subspecies the heath hare ( Lepus timidus sylvaticus ), along with samples from two mountain hares ( Lepus timidus timidus ) and two brown hares ( Lepus …
View article: Top3α is the replicative topoisomerase in mitochondrial DNA replication
Top3α is the replicative topoisomerase in mitochondrial DNA replication Open
Mitochondrial DNA has been investigated for nearly fifty years, but many aspects of the maintenance of this essential small genome remain unknown. Like any genome, mammalian mitochondrial DNA requires the function of topoisomerases to coun…
View article: Molecular phenotyping uncovers differences in basic housekeeping functions among closely related species of hares (Lepus spp., Lagomorpha: Leporidae)
Molecular phenotyping uncovers differences in basic housekeeping functions among closely related species of hares (Lepus spp., Lagomorpha: Leporidae) Open
Speciation is a fundamental evolutionary process, which results in genetic differentiation of populations and manifests as discrete morphological, physiological and behavioral differences. Each species has had its own evolutionary trajecto…
View article: Comparative metagenomics of phytoplankton blooms after nutrient enrichment of oligotrophic marine waters
Comparative metagenomics of phytoplankton blooms after nutrient enrichment of oligotrophic marine waters Open
Increasing anthropogenic pressures on the coastal marine environments impact these ecosystems via a variety of mechanisms including nutrient loading, leading to eutrophication and increases in algal blooms. Here, we use a metagenomics appr…
View article: Hybridization with mountain hares increases the functional allelic repertoire in brown hares
Hybridization with mountain hares increases the functional allelic repertoire in brown hares Open
Brown hares ( Lepus europaeus Pallas) are able to hybridize with mountain hares ( L. timidus Linnaeus) and produce fertile offspring, which results in cross-species gene flow. However, not much is known about the functional significance of…
View article: The Type and Source of Reactive Oxygen Species Influences the Outcome of Oxidative Stress in Cultured Cells
The Type and Source of Reactive Oxygen Species Influences the Outcome of Oxidative Stress in Cultured Cells Open
Oxidative stress can be modeled using various different experimental approaches, such as exposing the cells or organisms to oxidative chemicals. However, the actual effects of these chemicals, outside of the immediate measured effect, have…
View article: Genomes of the willow-galling sawflies <i>Euura lappo</i> and <i>Eupontania aestiva</i> (Hymenoptera: Tenthredinidae): a resource for research on ecological speciation, adaptation, and gall induction
Genomes of the willow-galling sawflies <i>Euura lappo</i> and <i>Eupontania aestiva</i> (Hymenoptera: Tenthredinidae): a resource for research on ecological speciation, adaptation, and gall induction Open
Hymenoptera is a hyperdiverse insect order represented by over 153,000 different species. As many hymenopteran species perform various crucial roles for our environments, such as pollination, herbivory, and parasitism, they are of high eco…
View article: The best of both worlds: Shortcutting evolution through adaptive hybridization in hares
The best of both worlds: Shortcutting evolution through adaptive hybridization in hares Open
Brown hares ( Lepus europaeus Pallas) are able to hybridize with mountain hares ( L. timidus Linnaeus) and produce fertile offspring, which results in cross-species gene flow. However, not much is known about the functional significance of…
View article: The type and source of reactive oxygen species influences the outcome of oxidative stress in cultured cells
The type and source of reactive oxygen species influences the outcome of oxidative stress in cultured cells Open
Oxidative stress can be modeled using various different experimental approaches, such as exposing the cells or organisms to oxidative chemicals. However, the actual effects of these chemicals, outside of the immediate measured effect, have…
View article: Desert plant bacteria reveal host influence and beneficial plant growth properties
Desert plant bacteria reveal host influence and beneficial plant growth properties Open
Deserts, such as those found in Saudi Arabia, are one of the most hostile places for plant growth. However, desert plants are able to impact their surrounding microbial community and select beneficial microbes that promote their growth und…
View article: The Genome Sequence of the Wild Tomato Solanum pimpinellifolium Provides Insights Into Salinity Tolerance
The Genome Sequence of the Wild Tomato Solanum pimpinellifolium Provides Insights Into Salinity Tolerance Open
Solanum pimpinellifolium, a wild relative of cultivated tomato, offers a wealth of breeding potential for desirable traits such as tolerance to abiotic and biotic stresses. Here, we report the genome assembly and annotation of S. pimpinell…
View article: Finding Nemo’s Genes: A chromosome‐scale reference assembly of the genome of the orange clownfish <i>Amphiprion percula</i>
Finding Nemo’s Genes: A chromosome‐scale reference assembly of the genome of the orange clownfish <i>Amphiprion percula</i> Open
The iconic orange clownfish, Amphiprion percula , is a model organism for studying the ecology and evolution of reef fishes, including patterns of population connectivity, sex change, social organization, habitat selection and adaptation t…