Cristina Andrés‐Lacueva
YOU?
Author Swipe
View article: Effect of a polyphenol-rich dietary pattern on subjects aged ≥ 60 years with higher levels of inflammatory markers: insights into microbiome and metabolome
Effect of a polyphenol-rich dietary pattern on subjects aged ≥ 60 years with higher levels of inflammatory markers: insights into microbiome and metabolome Open
Background: Aging may be associated with low-grade chronic inflammation (“inflammaging”) and gut microbiome alterations. Dietary polyphenols have been proposed as modulators of these processes. To explore the effects of a polyphenol-rich (…
View article: Effect of plant-based foods and (poly)phenol supplementation on gut-microbiota metabolism in participants with overweight or obesity and cardiometabolic risk: a study protocol for a single-blind, parallel and randomised controlled trial
Effect of plant-based foods and (poly)phenol supplementation on gut-microbiota metabolism in participants with overweight or obesity and cardiometabolic risk: a study protocol for a single-blind, parallel and randomised controlled trial Open
Introduction Dietary (poly)phenols have beneficial properties that may play a relevant role in the management of overweight/obesity and cardiometabolic risk factors, modulating physiological and molecular pathways involved in energy metabo…
View article: Metabolite Biomarkers Linking a High-Fiber Rye Intervention with Cardiometabolic Risk Factors: The RyeWeight Study
Metabolite Biomarkers Linking a High-Fiber Rye Intervention with Cardiometabolic Risk Factors: The RyeWeight Study Open
Wholegrain rye, considered one of the cereals with the highest content of dietary fiber and bioactive compounds, has been linked with reduced risk of cardiometabolic diseases. Thus, biomarkers reflecting its intake and/or the metabolic eff…
View article: Blood serum from individuals with Alzheimer’s disease alters microglial phagocytosis in vitro
Blood serum from individuals with Alzheimer’s disease alters microglial phagocytosis in vitro Open
In Alzheimer’s disease, microglial phagocytosis is engaged in the pathogenesis as it clears abnormal protein accumulations, debris, and apoptotic cells in the early stages of Alzheimer’s disease, but fuels neuroinflammation and accelerates…
View article: TAS2R5 and TAS2R38 are bitter taste receptors whose colonic expressions could play important roles in age-associated processes
TAS2R5 and TAS2R38 are bitter taste receptors whose colonic expressions could play important roles in age-associated processes Open
Ageing disrupts how our bodies process nutrients, leading to deregulation of nutrient-sensing and increased inflammation. Dietary interventions can promote healthy ageing, which demonstrates the importance of both metabolism and the gastro…
View article: Association between dairy products intake and frailty transitions in older adults: The InCHIANTI cohort study
Association between dairy products intake and frailty transitions in older adults: The InCHIANTI cohort study Open
Dairy products, such as milk, yogurt, and cheese, are unlikely to play a predominant role in frailty development in an Italian community-dwelling older population. However, it is advisable to maintain a moderate consumption of dairy produc…
View article: Extended recommendations on the nomenclature for microbial catabolites of dietary (poly)phenols, with a focus on isomers
Extended recommendations on the nomenclature for microbial catabolites of dietary (poly)phenols, with a focus on isomers Open
There is an increasing body of evidence indicating that phenolic compounds derived from microbiota-mediated breakdown of dietary (poly)phenolics in the colon are at least partially responsible for the beneficial effects of a plant-based di…
View article: Prediagnostic Plasma Nutrimetabolomics and Prostate Cancer Risk: A Nested Case–Control Analysis Within the EPIC Study
Prediagnostic Plasma Nutrimetabolomics and Prostate Cancer Risk: A Nested Case–Control Analysis Within the EPIC Study Open
Background and Objective: Nutrimetabolomics may reveal novel insights into early metabolic alterations and the role of dietary exposures on prostate cancer (PCa) risk. We aimed to prospectively investigate the associations between plasma m…
View article: Prostate cancer risk biomarkers from large cohort and prospective metabolomics studies: A systematic review
Prostate cancer risk biomarkers from large cohort and prospective metabolomics studies: A systematic review Open
View article: A Comprehensive LC–MS Metabolomics Assay for Quantitative Analysis of Serum and Plasma
A Comprehensive LC–MS Metabolomics Assay for Quantitative Analysis of Serum and Plasma Open
Background/Objectives: Targeted metabolomics is often criticized for the limited metabolite coverage that it offers. Indeed, most targeted assays developed or used by researchers measure fewer than 200 metabolites. In an effort to both exp…
View article: A (poly)phenol-rich diet reduces serum and faecal calprotectin in older adults with increased intestinal permeability: the MaPLE randomised controlled trial
A (poly)phenol-rich diet reduces serum and faecal calprotectin in older adults with increased intestinal permeability: the MaPLE randomised controlled trial Open
View article: Effect of an 8-Week Intervention With a (Poly)phenol-Rich Diet on Intestinal Permeability and Inflammatory Markers in Older Subjects
Effect of an 8-Week Intervention With a (Poly)phenol-Rich Diet on Intestinal Permeability and Inflammatory Markers in Older Subjects Open
Objectives: Older subjects are more prone to develop inflammation and intestinal permeability (IP). Diets rich in (poly)phenols could represent a potential strategy to reduce IP. The goal of the present study was to test the hypothesis tha…
View article: Coffee polyphenols ameliorate early-life stress-induced cognitive deficits in male mice
Coffee polyphenols ameliorate early-life stress-induced cognitive deficits in male mice Open
Stress exposure during the sensitive period of early development has been shown to program the brain and increases the risk to develop cognitive deficits later in life. We have shown earlier that early-life stress (ES) leads to cognitive d…
View article: Association of dietary and nutritional factors with cognitive decline, dementia, and depressive symptomatology in older individuals according to a neurogenesis-centred biological susceptibility to brain ageing
Association of dietary and nutritional factors with cognitive decline, dementia, and depressive symptomatology in older individuals according to a neurogenesis-centred biological susceptibility to brain ageing Open
Hippocampal neurogenesis (HN) occurs throughout the life course and is important for memory and mood. Declining with age, HN plays a pivotal role in cognitive decline (CD), dementia, and late-life depression, such that altered HN could rep…
View article: Metabolome biomarkers linking dietary fibre intake with cardiometabolic effects: results from the Danish Diet, Cancer and Health-Next Generations MAX study
Metabolome biomarkers linking dietary fibre intake with cardiometabolic effects: results from the Danish Diet, Cancer and Health-Next Generations MAX study Open
Three metabolites were consistently associated with self-reported dietary fibre intake in a one-year observational study. Predicted fiber intake, using these metabolites, showed a differential readout with relevance for cardiometabolic hea…
View article: A Mediterranean Diet‐Based Metabolomic Score and Cognitive Decline in Older Adults: A Case–Control Analysis Nested within the Three‐City Cohort Study
A Mediterranean Diet‐Based Metabolomic Score and Cognitive Decline in Older Adults: A Case–Control Analysis Nested within the Three‐City Cohort Study Open
Scope Evidence on the Mediterranean diet (MD) and age‐related cognitive decline (CD) is still inconclusive partly due to self‐reported dietary assessment. The aim of the current study is to develop an MD‐ metabolomic score (MDMS) and inves…
View article: Plasma metabolomic profiles of plant-based dietary indices reveal potential pathways for metabolic syndrome associations
Plasma metabolomic profiles of plant-based dietary indices reveal potential pathways for metabolic syndrome associations Open
View article: Intake of the Total, Classes, and Subclasses of (Poly)Phenols and Risk of Prostate Cancer: A Prospective Analysis of the EPIC Study
Intake of the Total, Classes, and Subclasses of (Poly)Phenols and Risk of Prostate Cancer: A Prospective Analysis of the EPIC Study Open
Existing epidemiological evidence regarding the potential role of (poly)phenol intake in prostate cancer (PCa) risk is scarce and, in the case of flavonoids, it has been suggested that their intake may increase PCa risk. We investigated th…
View article: Biomarkers of Berry Intake: Systematic Review Update
Biomarkers of Berry Intake: Systematic Review Update Open
Berries are rich in (poly)phenols, and these compounds may be beneficial to human health. Estimating berry consumption through self-reported questionnaires has been challenging due to compliance issues and a lack of precision. Estimation v…
View article: Adherence to Mediterranean Diet and Response to an Exercise Program to Prevent Hospitalization-Associated Disability in Older Adults: A Secondary Analysis from a Randomized Controlled Trial
Adherence to Mediterranean Diet and Response to an Exercise Program to Prevent Hospitalization-Associated Disability in Older Adults: A Secondary Analysis from a Randomized Controlled Trial Open
Older individuals over age 75 with low MedDiet adherence were likely to benefit more from a physical exercise and health education intervention.
View article: Quantitative plasma profiling by 1H NMR-based metabolomics: impact of sample treatment
Quantitative plasma profiling by 1H NMR-based metabolomics: impact of sample treatment Open
Introduction: There is evidence that sample treatment of blood-based biosamples may affect integral signals in nuclear magnetic resonance-based metabolomics. The presence of macromolecules in plasma/serum samples makes investigating low-mo…
View article: Correction: Biomarkers of moderate alcohol intake and alcoholic beverages: a systematic literature review
Correction: Biomarkers of moderate alcohol intake and alcoholic beverages: a systematic literature review Open
View article: Biomarkers of moderate alcohol intake and alcoholic beverages: a systematic literature review
Biomarkers of moderate alcohol intake and alcoholic beverages: a systematic literature review Open
View article: Dietary polyphenols, metabolic syndrome and cardiometabolic risk factors: An observational study based on the DCH-NG subcohort
Dietary polyphenols, metabolic syndrome and cardiometabolic risk factors: An observational study based on the DCH-NG subcohort Open
View article: Dietary Sources of Anthocyanins and Their Association with Metabolome Biomarkers and Cardiometabolic Risk Factors in an Observational Study
Dietary Sources of Anthocyanins and Their Association with Metabolome Biomarkers and Cardiometabolic Risk Factors in an Observational Study Open
Anthocyanins (ACNs) are (poly)phenols associated with reduced cardiometabolic risk. Associations between dietary intake, microbial metabolism, and cardiometabolic health benefits of ACNs have not been fully characterized. Our aims were to …
View article: Perceptual blindless in nutrition: We are in a critical time to be connected
Perceptual blindless in nutrition: We are in a critical time to be connected Open
Our health and well‐being are affected by our food systems. The new nutrition reality has been linked to complex food systems, interrelated with several pathways and determinants, including physical, socioeconomic, environmental, and ecolo…
View article: Apolipoprotein E gene variants shape the association between dietary fibre intake and cognitive decline risk in community-dwelling older adults
Apolipoprotein E gene variants shape the association between dietary fibre intake and cognitive decline risk in community-dwelling older adults Open
Background healthy dietary patterns have been associated with lower risk for age-related cognitive decline. However, little is known about the specific role of dietary fibre on cognitive decline in older adults. Objective this study aimed …
View article: Plasma anthocyanins and their metabolites reduce in vitro migration of pancreatic cancer cells, PANC-1, in a FAK- and NF-kB dependent manner: Results from the ATTACH-study a randomized, controlled, crossover trial in healthy subjects
Plasma anthocyanins and their metabolites reduce in vitro migration of pancreatic cancer cells, PANC-1, in a FAK- and NF-kB dependent manner: Results from the ATTACH-study a randomized, controlled, crossover trial in healthy subjects Open
Pancreatic cancer is primarily considered to be a metastatic disease with a low 5-year survival rate. We aimed to detect if plasma-isolated anthocyanins and their metabolites (PAMs) modulate pancreatic cancer cells migration and to describ…
View article: Urinary and Daily Assumption of Polyphenols and Hip-Fracture Risk: Results from the InCHIANTI Study
Urinary and Daily Assumption of Polyphenols and Hip-Fracture Risk: Results from the InCHIANTI Study Open
A high polyphenol intake has been associated with higher bone-mineral density. In contrast, we recently demonstrated that the urinary levels of these micronutrients were associated with the long-term accelerated deterioration of the bone. …
View article: Exploration of the Gut–Brain Axis through Metabolomics Identifies Serum Propionic Acid Associated with Higher Cognitive Decline in Older Persons
Exploration of the Gut–Brain Axis through Metabolomics Identifies Serum Propionic Acid Associated with Higher Cognitive Decline in Older Persons Open
The gut microbiome is involved in nutrient metabolism and produces metabolites that, via the gut–brain axis, signal to the brain and influence cognition. Human studies have so far had limited success in identifying early metabolic alterati…