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View article: <scp>SNX17</scp> Regulates Antigen Internalisation and Phagosomal Maturation by Dendritic Cells
<span>SNX17</span> Regulates Antigen Internalisation and Phagosomal Maturation by Dendritic Cells Open
Antigen cross‐presentation is the process whereby small peptides derived from exogenous antigens are attached to MHC‐I molecules triggering CD8+ T lymphocyte activation. The endocytic route of dendritic cells (DCs) is highly specialised fo…
View article: Efficient Cholesterol Transport in Dendritic Cells Defines Optimal Exogenous Antigen Presentation and Toxoplasma gondii Proliferation
Efficient Cholesterol Transport in Dendritic Cells Defines Optimal Exogenous Antigen Presentation and Toxoplasma gondii Proliferation Open
Dendritic cells are the most powerful antigen-presenting cells of the immune system. They present exogenous antigens associated with Major Histocompatibility Complex (MHC) Class II molecules through the classical pathway to stimulate CD4+ …
View article: SNX17 regulates antigen internalization and phagosomal maturation by dendritic cells
SNX17 regulates antigen internalization and phagosomal maturation by dendritic cells Open
Cross-presentation is the process whereby antigenic peptides derived from exogenous antigens are associated to MHC class I molecules triggering the activation of CD8+ T lymphocytes. The endocytic route of dendritic cells (DCs) is strongly …
View article: Differential requirement of Rab22a for the recruitment of ER-derived proteins to phagosomes and endosomes in dendritic cells
Differential requirement of Rab22a for the recruitment of ER-derived proteins to phagosomes and endosomes in dendritic cells Open
The recruitment of endoplasmic reticulum (ER) components to dendritic cell (DC) phagosomes and endosomes is a crucial event to achieve efficient cross-presentation of exogenous antigens. We have previously identified the small GTPase Rab22…
View article: Rab22a controls <scp>MHC</scp> ‐I intracellular trafficking and antigen cross‐presentation by dendritic cells
Rab22a controls <span>MHC</span> ‐I intracellular trafficking and antigen cross‐presentation by dendritic cells Open