Cristina Luceri
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View article: Salivary oxidative stress persists in inflammatory bowel disease regardless of biological treatment response
Salivary oxidative stress persists in inflammatory bowel disease regardless of biological treatment response Open
Background Uncontrolled oxidative stress contributes to the pathogenesis of inflammatory bowel disease (IBD), yet its association with disease activity and response to biological therapy, has never been studied in saliva. We investigated w…
View article: Development, characterization and in vitro assessment of a novel self-microemulsifying drug delivery system to increase cannabidiol intestinal bioaccessibility
Development, characterization and in vitro assessment of a novel self-microemulsifying drug delivery system to increase cannabidiol intestinal bioaccessibility Open
A new self-microemulsifying drug delivery system (SMEDDS) was developed as a rational alternative to the conventional oral forms of cannabidiol (CBD). The pseudoternary phase diagram was built after excipient screening based on solubility …
View article: Anti-CGRP monoclonal antibodies counteract establishment of food aversive memories and chemotherapy-induced anorexia and weight loss
Anti-CGRP monoclonal antibodies counteract establishment of food aversive memories and chemotherapy-induced anorexia and weight loss Open
Glutamatergic neurons of external lateral parabrachial nucleus co-expressing calcitonin gene related peptide (elPBCGRP) negatively regulate food intake and establish food aversive memories. They also promote malaise-dependent an…
View article: Editorial: Model organisms in predictive toxicology 2023
Editorial: Model organisms in predictive toxicology 2023 Open
No abstract available
View article: Vaginal miR-210-3p as a potential biomarker for pregnancies complicated by early fetal growth restriction: A proof-of-concept case-control study
Vaginal miR-210-3p as a potential biomarker for pregnancies complicated by early fetal growth restriction: A proof-of-concept case-control study Open
View article: P1173 Results of salvage ileal-pouch-anal anastomosis surgery in Ulcerative Colitis patients with restorative proctocolectomy
P1173 Results of salvage ileal-pouch-anal anastomosis surgery in Ulcerative Colitis patients with restorative proctocolectomy Open
Background Restorative proctocolectomy (PCT) with ileal-pouch-anal anastomosis (IPAA) is the surgical treatment in medically refractory ulcerative colitis (UC). Short and long-term complications are septic (abscess/fistula), inflammatory (…
View article: Prenatal ethanol exposure impairs hippocampal plasticity and cognition in adolescent mice
Prenatal ethanol exposure impairs hippocampal plasticity and cognition in adolescent mice Open
View article: Reflux disease: a new multicomponent solution for a multifaceted problem
Reflux disease: a new multicomponent solution for a multifaceted problem Open
No abstract available
View article: Arthrospira platensis F&M-C265 reduces cardiometabolic risk factors in rats fed a high fat diet
Arthrospira platensis F&M-C265 reduces cardiometabolic risk factors in rats fed a high fat diet Open
View article: First Exploration of the Altered Microbial Gut–Lung Axis in the Pathogenesis of Human Refractory Chronic Cough
First Exploration of the Altered Microbial Gut–Lung Axis in the Pathogenesis of Human Refractory Chronic Cough Open
Purpose Cough represents a natural mechanism that plays an important defensive role in the respiratory tract, but in some conditions, it may become persistent, nonproductive, and harmful. In general, refractory chronic cough (RCC) occurs i…
View article: FROM PRECLINICAL TO CLINICAL EVIDENCE: EXPLORING THE MULTIPLE PERSPECTIVES AND HEALING POWER OF BOSWELLIA SERRATA ROXB. EX COLEBR
FROM PRECLINICAL TO CLINICAL EVIDENCE: EXPLORING THE MULTIPLE PERSPECTIVES AND HEALING POWER OF BOSWELLIA SERRATA ROXB. EX COLEBR Open
Boswellia serrata Roxb. ex Colebr. is a species belonging to the Burseraceae family, typical of dry environments of the Indian region. The oil-gum-resin, obtained from the trunk and thick branches, is known in phytotherapy for the volatile…
View article: Technical Evaluation of a New Medical Device Based on Rigenase in the Treatment of Chronic Skin Lesions
Technical Evaluation of a New Medical Device Based on Rigenase in the Treatment of Chronic Skin Lesions Open
Chronic wound is characterized by slow healing time, persistence, and abnormal healing progress. Therefore, serious complications can lead at worst to the tissue removal. In this scenario, there is an urgent need for an ideal dressing capa…
View article: Correction to “Cyclic Acetals as Novel Long-Lasting Mosquito Repellents”
Correction to “Cyclic Acetals as Novel Long-Lasting Mosquito Repellents” Open
ADVERTISEMENT RETURN TO ARTICLES ASAPPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to “Cyclic Acetals as Novel Long-Lasting Mosquito Repellents”Immacolata IovinellaImmacolata IovinellaMore by Immacolata I…
View article: Ethanol-induced AMPA alterations are mediated by mGLU5 receptors through miRNA upregulation in hippocampal slices
Ethanol-induced AMPA alterations are mediated by mGLU5 receptors through miRNA upregulation in hippocampal slices Open
View article: Chitosan coated niosomes for nose-to-brain delivery of clonazepam: Formulation, stability and permeability studies.
Chitosan coated niosomes for nose-to-brain delivery of clonazepam: Formulation, stability and permeability studies. Open
Crossing the Blood Brain Barrier constitutes a challenge in drug administration to the brain. In this context, nose-to-brain delivery is explored as an alternative route in the treatment of central nervous system disorders, and nanotechnol…
View article: A comparative study of metabolites profiles, anti-inflammatory and antioxidant activity of methanolic extracts from three Arthrospira strains in RAW 264.7 macrophages
A comparative study of metabolites profiles, anti-inflammatory and antioxidant activity of methanolic extracts from three Arthrospira strains in RAW 264.7 macrophages Open
View article: Tisochrysis lutea F&M-M36 Mitigates Risk Factors of Metabolic Syndrome and Promotes Visceral Fat Browning through β3-Adrenergic Receptor/UCP1 Signaling
Tisochrysis lutea F&M-M36 Mitigates Risk Factors of Metabolic Syndrome and Promotes Visceral Fat Browning through β3-Adrenergic Receptor/UCP1 Signaling Open
Pre-metabolic syndrome (pre-MetS) may represent the best transition phase to start treatments aimed at reducing cardiometabolic risk factors of MetS. In this study, we investigated the effects of the marine microalga Tisochrysis lutea F&M-…
View article: Impact of Preoperative Immunonutrition on Oxidative Stress and Gut Barrier Function in Surgical Patients with Crohn’s Disease
Impact of Preoperative Immunonutrition on Oxidative Stress and Gut Barrier Function in Surgical Patients with Crohn’s Disease Open
Several international guidelines recommend a peri-operative immunonutrition (IN) support for patients care in elective colorectal surgery, to reduce postoperative complications, particularly infections. In Crohn’s patients, is also used to…
View article: Cyclic Acetals as Novel Long-Lasting Mosquito Repellents
Cyclic Acetals as Novel Long-Lasting Mosquito Repellents Open
The use of skin repellents against hematophagous mosquitoes is an important personal protection practice wherever these insects are abundant and where they are vectors of diseases. DEET and Icaridin are the major synthetic insect repellent…
View article: Niosomes Functionalized with a Synthetic Carbohydrate Binding Agent for Mannose-Targeted Doxorubicin Delivery
Niosomes Functionalized with a Synthetic Carbohydrate Binding Agent for Mannose-Targeted Doxorubicin Delivery Open
Niosomes are a potential tool for the development of active targeted drug delivery systems (DDS) for cancer therapy because of their excellent behaviour in encapsulating antitumorals and the possibility to easily functionalise their surfac…
View article: C1qa Muscularis Macrophages Regulate Gastrointestinal Motility Through Close Association With Enteric Neurons
C1qa Muscularis Macrophages Regulate Gastrointestinal Motility Through Close Association With Enteric Neurons Open
View article: A Comparison between Open and Minimally Invasive Techniques for the Resection of Colorectal Liver Metastasis
A Comparison between Open and Minimally Invasive Techniques for the Resection of Colorectal Liver Metastasis Open
The liver is the most common site of colorectal cancer metastasis. Liver surgery is a cornerstone in treatment, with progressive expansion of minimally invasive surgery (MIS). This study aims to compare short- and long-term outcomes of ope…
View article: New regulation on medical devices made of substances: Opportunities and challenges for pharmacological and toxicological research
New regulation on medical devices made of substances: Opportunities and challenges for pharmacological and toxicological research Open
The Medical Device (MD) Regulation EU 2017/745 (MDR) has provided a completely new and more robust regulatory framework at guarantee of the safety and efficacy of therapeutic options accessing the market. At the same time, the MDR poses se…
View article: Low levels of miR-34c in nasal washings as a candidate marker of aggressive disease in wood and leather exposed workers with sinonasal intestinal-type adenocarcinomas (ITACs)
Low levels of miR-34c in nasal washings as a candidate marker of aggressive disease in wood and leather exposed workers with sinonasal intestinal-type adenocarcinomas (ITACs) Open
View article: Crohn’s disease recurrence updates: first surgery vs. surgical relapse patients display different profiles of ileal microbiota and systemic microbial-associated inflammatory factors
Crohn’s disease recurrence updates: first surgery vs. surgical relapse patients display different profiles of ileal microbiota and systemic microbial-associated inflammatory factors Open
Background and aims Crohn’s disease (CD) pathogenesis is still unclear. Remodeling in mucosal microbiota and systemic immunoregulation may represent an important component in tissue injury. Here, we aim to characterize the ileal microbiota…
View article: Is the age at surgery in Crohn’s disease clinically relevant? Differences and peculiarities: a wide single centre experience after long-term follow-up
Is the age at surgery in Crohn’s disease clinically relevant? Differences and peculiarities: a wide single centre experience after long-term follow-up Open
View article: Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells via Tryptophan 2,3 Dioxygenase
Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells via Tryptophan 2,3 Dioxygenase Open
In addition to its well-established immunosuppressive actions, tryptophan 2,3-dioxygenase (TDO) appears to elicit direct effects on tumor cell function. Although TDO has been associated with cancer stemness, its involvement in melanoma ste…
View article: Involvement of MIR-126 and MMP9 in the Pathogenesis of Intra-Abdominal Fistulizing Crohn’s Disease: A Brief Research Report
Involvement of MIR-126 and MMP9 in the Pathogenesis of Intra-Abdominal Fistulizing Crohn’s Disease: A Brief Research Report Open
Background Intra-abdominal fistulas are complications that affect a significant proportion of Crohn’s disease patients, often requiring surgery. The aim of the present work was to correlate the occurrence of intestinal fistulization to the…
View article: Acute Rapamycin Rescues the Hyperexcitable Phenotype of Accumbal Medium Spiny Neurons in the Valproic Acid Rat Model of Autism Spectrum Disorder
Acute Rapamycin Rescues the Hyperexcitable Phenotype of Accumbal Medium Spiny Neurons in the Valproic Acid Rat Model of Autism Spectrum Disorder Open
View article: Role of Macrophages and Mast Cells as Key Players in the Maintenance of Gastrointestinal Smooth Muscle Homeostasis and Disease
Role of Macrophages and Mast Cells as Key Players in the Maintenance of Gastrointestinal Smooth Muscle Homeostasis and Disease Open