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View article: V-Notes Sentinel Lymph Node Staging for Endometrial Cancer: A Systematic Review
V-Notes Sentinel Lymph Node Staging for Endometrial Cancer: A Systematic Review Open
Background/Objectives: Sentinel lymph node (SLN) mapping has become a standard approach in the surgical staging of early-stage endometrial cancer, aiming to reduce the morbidity associated with full lymphadenectomy while preserving diagnos…
View article: Congenital Thrombophilia in Chronic Thromboembolic Pulmonary Hypertension (CTEPH): A Systematic Review of Prevalence, Clinical Phenotype, and Surgical Outcomes
Congenital Thrombophilia in Chronic Thromboembolic Pulmonary Hypertension (CTEPH): A Systematic Review of Prevalence, Clinical Phenotype, and Surgical Outcomes Open
Background and Objectives: Congenital thrombophilias are biologically plausible contributors to chronic thromboembolic pulmonary hypertension (CTEPH), yet their frequency and clinical impact remain uncertain. We undertook a systematic revi…
View article: V-Notes Sentinel Lymph Node Staging for Endometrial Cancer: a review.
V-Notes Sentinel Lymph Node Staging for Endometrial Cancer: a review. Open
Background/Objectives: Sentinel lymph node (SLN) mapping has become a standard approach in the surgical staging of early-stage endometrial cancer, aiming to reduce the morbidity associated with full lymphadenectomy while preserving diagnos…
View article: The Efficacy of Modified Laparoscopic Burch Procedure Using a Single Stitch on Each Side of the Urethra for the Treatment of Stress Urinary Incontinence
The Efficacy of Modified Laparoscopic Burch Procedure Using a Single Stitch on Each Side of the Urethra for the Treatment of Stress Urinary Incontinence Open
Background and Objectives: This study aimed to evaluate the efficacy and safety of modified laparoscopic Burch intervention over a 24-month follow-up period. Materials and Methods: We performed a retrospective cohort evaluation including a…
View article: The Effectiveness of Mesh-Less Pectopexy in the Treatment of Vaginal Apical Prolapse—A Prospective Study
The Effectiveness of Mesh-Less Pectopexy in the Treatment of Vaginal Apical Prolapse—A Prospective Study Open
Objectives: Pelvic organ prolapse (POP) is a common condition affecting women, often requiring surgical intervention. Laparoscopic pectopexy has gained popularity, but there is ongoing debate about the efficacy and safety of mesh versus th…
View article: Quality of Life Assessment After Pelvic Prolapse Surgery With and Without Mesh: A Literature Review
Quality of Life Assessment After Pelvic Prolapse Surgery With and Without Mesh: A Literature Review Open
Background/Objectives: The quality of life (QoL) in patients undergoing pelvic prolapse surgery is a critical area of research in urogynecology. Pelvic organ prolapse (POP) is a prevalent condition affecting a significant number of women, …
View article: Quality of Life Assessment After Pelvic Prolapse Surgery with and Without Mesh. A Literature Review
Quality of Life Assessment After Pelvic Prolapse Surgery with and Without Mesh. A Literature Review Open
Background/Objectives: The quality of life (QoL) in patients undergoing pelvic prolapse surgery is a critical area of research in urogynecology. Pelvic organ prolapse (POP) is a prevalent condition affecting a significant number of women, …
View article: Complications of Pelvic Prolapse Surgery Using Mesh: A Systematic Review
Complications of Pelvic Prolapse Surgery Using Mesh: A Systematic Review Open
Background: Pelvic organ prolapse (POP) is a public health problem that influences millions of women around the globe, and it has a significant impact on the quality of life. From the FDA statement regarding the complications of using mesh…
View article: Impact of SARS-CoV-2 Pandemic on the Diagnosis of Cervical Cancer and Precursor Lesions—A Single-Center Retrospective Study
Impact of SARS-CoV-2 Pandemic on the Diagnosis of Cervical Cancer and Precursor Lesions—A Single-Center Retrospective Study Open
Background and Objectives: Our aim was to perform a retrospective analysis of the volume of cervical screening tests, the number of patients treated with an excision method, and the incidence of invasive and non-invasive cervical during a …
View article: Heterogeneity of Cervical Cancer-Associated Tertiary Lymphoid Structures (TLSs) and Their Specific Interrelation With Clinicopathological Parameters
Heterogeneity of Cervical Cancer-Associated Tertiary Lymphoid Structures (TLSs) and Their Specific Interrelation With Clinicopathological Parameters Open
View article: Impact Of SARS-CoV-2 Pandemic On The Diagnosis Of Cervical Cancer And Precursor Lesions - A Single Center Retrospective Study
Impact Of SARS-CoV-2 Pandemic On The Diagnosis Of Cervical Cancer And Precursor Lesions - A Single Center Retrospective Study Open
Objective: The aim of our study was to perform a retrospective analysis of the volume of cervical screening tests, the number of patients treated with an excision method, and the incidence of invasive and non-invasive cervical during a pan…
View article: The Impact of Laparoscopic Myomectomy on Pregnancy Outcomes: A Systematic Review
The Impact of Laparoscopic Myomectomy on Pregnancy Outcomes: A Systematic Review Open
Study objective: The objective of this systematic review is to investigate the impact of laparoscopic myomectomy techniques on pregnancy outcomes, with a specific focus on the correlation between the type of suture used during the procedur…
View article: Risk Factors of Thrombophilia-Related Mutations for Early and Late Pregnancy Loss
Risk Factors of Thrombophilia-Related Mutations for Early and Late Pregnancy Loss Open
Background and Objectives: This retrospective cohort study investigates the role of genetic thrombophilia in pregnant women experiencing early pregnancy loss compared to those with late pregnancy loss. Materials and Methods: Participants w…
View article: Evaluating Patient Preferences and Clinical Outcomes in Stress Urinary Incontinence Treatment: A Short-Term Follow-Up Study of the Transobturator Tape Procedure and Pubourethral Ligament Plication (a Minimally Invasive Technique)
Evaluating Patient Preferences and Clinical Outcomes in Stress Urinary Incontinence Treatment: A Short-Term Follow-Up Study of the Transobturator Tape Procedure and Pubourethral Ligament Plication (a Minimally Invasive Technique) Open
Objective: This study aims to provide an in-depth analysis of patient preferences and clinical outcomes associated with two surgical techniques for treating stress urinary incontinence (SUI): the transobturator suburethral sling (TOT) proc…
View article: Laparoscopic Pectopexy versus Vaginal Sacrospinous Ligament Fixation in the Treatment of Apical Prolapse
Laparoscopic Pectopexy versus Vaginal Sacrospinous Ligament Fixation in the Treatment of Apical Prolapse Open
Objectives: To compare the follow-up results of a sacrospinous ligament fixation (SSLF) technique for laparoscopic bilateral fixation of the vagina to the iliopectineal ligament via a PVDF-mesh (laparoscopic pectopexy technique, LP) in ter…
View article: Minimizing blood loss in laparoscopic myomectomy with temporary occlusion of the hypogastric artery
Minimizing blood loss in laparoscopic myomectomy with temporary occlusion of the hypogastric artery Open
Introduction Uterine leiomyomas are common benign pelvic tumors. Currently, laparoscopic myomectomy (LM) is the preferred treatment option for women in the fertile age group with symptomatic myomas. The authors hypothesize that combining L…
View article: Assessment of CA-125 First-Trimester Values as a Potential Screening Marker for Pre-Eclampsia
Assessment of CA-125 First-Trimester Values as a Potential Screening Marker for Pre-Eclampsia Open
Background: Pre-eclampsia is a major public health issue. Current screening methods are based on maternal characteristics and medical history, but complex predictive models combining different clinical and biochemical markers have been pro…
View article: A Systematic Review Assessing the Impact of Vitamin D Levels on Adult Patients with Lymphoid Malignancies
A Systematic Review Assessing the Impact of Vitamin D Levels on Adult Patients with Lymphoid Malignancies Open
Vitamin D deficiency has been correlated with various conditions, including the risk of developing lymphoid malignancies. This systematic review aimed to assess the association between vitamin D levels at diagnosis of lymphoid malignancies…
View article: Role of CA-125 Level as a Marker in the Management of Severe Pre-Eclampsia
Role of CA-125 Level as a Marker in the Management of Severe Pre-Eclampsia Open
Background and Objectives: Hypertensive disorders of pregnancy remain one of the leading causes of morbidity and mortality in maternal–fetal medicine worldwide, particularly in low-resource settings. Despite extensive research in the last …
View article: Assessing Pretransplant and Posttransplant Therapy Response in Multiple Myeloma Patients
Assessing Pretransplant and Posttransplant Therapy Response in Multiple Myeloma Patients Open
Multiple myeloma (MM) is a hematologic cancer defined by an abnormal development of clonal plasma cells in the bone marrow, releasing vast quantities of immunoglobulins and different proteins. In the majority of patients, MM remains incura…
View article: New Insights in the Diagnosis of Rare Adenocarcinoma Variants of the Cervix—Case Report and Review of Literature
New Insights in the Diagnosis of Rare Adenocarcinoma Variants of the Cervix—Case Report and Review of Literature Open
We report the case of a 29-year-old patient with low-grade squamous intraepithelial lesion (L-SIL), negative human papilloma virus (HPV), positive p16/Ki-67 dual-staining and colposcopy suggestive for severe dysplastic lesion. The patient …
View article: Case Report: Laparoscopic Isthmocele Repair on an 8 Weeks Pregnant Uterus
Case Report: Laparoscopic Isthmocele Repair on an 8 Weeks Pregnant Uterus Open
An isthmocele, also known as a caesarean scar defect, is a long-term complication of caesarean sections with an increasing incidence. Although is often asymptomatic, it is a novel recognised cause of abnormal uterine bleeding, and it is a …
View article: Role of Dual-Staining p16/Ki-67 in the Management of Patients under 30 Years with ASC-US/L-SIL
Role of Dual-Staining p16/Ki-67 in the Management of Patients under 30 Years with ASC-US/L-SIL Open
Patients diagnosed with low-grade squamous intraepithelial lesion ((L-SIL) or atypical squamous cells of undetermined significance (ASC-US) are subjected to additional investigations, such as colposcopy and biopsy, to rule out cervical int…
View article: Minimal Deviation Adenocarcinoma of the Uterine Cervix: Diagnostic Challenges and Recent Insights
Minimal Deviation Adenocarcinoma of the Uterine Cervix: Diagnostic Challenges and Recent Insights Open
View article: A Case Report of Left Atrial Isomerism in a Syndromic Context
A Case Report of Left Atrial Isomerism in a Syndromic Context Open
The objective of our paper is to underline the importance of assessing microarray genetic analysis for the detection of chromosomal abnormalities in rare cases such as left atrial isomerism, mostly in the context of antenatally detected sy…
View article: Endometriosis in Menopause—Renewed Attention on a Controversial Disease
Endometriosis in Menopause—Renewed Attention on a Controversial Disease Open
Endometriosis, an estrogen-dependent inflammatory disease characterized by the ectopic presence of endometrial tissue, has been the topic of renewed research and debate in recent years. The paradigm shift from the belief that endometriosis…
View article: Surgically Induced Menopause—A Practical Review of Literature
Surgically Induced Menopause—A Practical Review of Literature Open
Menopause can occur spontaneously (natural menopause) or it can be surgically induced by oophorectomy. The symptoms and complications related to menopause differ from one patient to another. We aimed to review the similarities and differen…
View article: Current opinions and recommendations for mesh use in gynecological surgery – literature review
Current opinions and recommendations for mesh use in gynecological surgery – literature review Open
Pelvic organ prolapse treatment remains controversial in current practice, given the abundance of procedures with or without uterine preservation and with or without the use of synthetic (polypropylene) mesh. We present a review of data av…
View article: p16/Ki-67 dual staining has a better accuracy than human papillomavirus (HPV) testing in women under 30 years old
p16/Ki-67 dual staining has a better accuracy than human papillomavirus (HPV) testing in women under 30 years old Open
Due to a high rate of transient human papillomavirus (HPV) infection, HPV genotyping has a low specificity for high-grade cervical lesions, especially in young women. p16/Ki-67 dual immunohistochemical staining can also be used for the det…
View article: Clinical and Histopathological Parameters Correlate with Microvessel Density but Not with Vascular Endothelial Growth Factor Expression in Ovarian Cancer
Clinical and Histopathological Parameters Correlate with Microvessel Density but Not with Vascular Endothelial Growth Factor Expression in Ovarian Cancer Open
Ovarian cancer malignancies have the worst prognosis among all gynecological malignancies. As angiogenesis represents a key step for tumor progression, vascular endothelial growth factor (VEGF) is one of the most discussed pro-angiogenic f…