Cristine Sortica da Costa

Endoscopic lavage after intraventricular haemorrhage in neonates in the UK (ENLIVEN-UK): study protocol for a national randomised-controlled trial Open

Saniya Mediratta, Ajai Chari, Cheryl Battersby, Patrick Bauserman, Emilia Caverly , et al. · 2025

ISRCTN Trial Registration: ISRCTN14018410.

Perceptions of genomic newborn screening: a cross-sectional survey conducted with UK medical students Open

Lydia Seed, Anna Mae Scott, Amanda Pichini, Michelle Peter, Shereen Tadros , et al. · 2024

Background With the potential to identify a vast number of rare diseases soon after birth, genomic newborn screening (gNBS) could facilitate earlier interventions and improve health outcomes. Designing a gNBS programme will involve balanci…

Cerebral autoregulation in pediatric and neonatal intensive care: A scoping review Open

Marta Fedriga, Silvia Martini, F. Iodice, Cristine Sortica da Costa, Stefano Pezzato , et al. · 2024

Deranged cerebral autoregulation (CA) is associated with worse outcome in adult brain injury. Strategies for monitoring CA and maintaining the brain at its ‘best CA status’ have been implemented, however, this approach has not yet develope…

Neonatal somatic oxygenation and perfusion assessment using near-infrared spectroscopy Open

Elisabeth M. W. Kooi, Jonathan Mintzer, Christopher J. Rhee, Ebru Ergenekon, Christoph E. Schwarz , et al. · 2024

Preparing tomorrow's doctors for the genomics era: A nationwide survey of UK medical students Open

Lydia Seed, Anna Mae Scott, Michelle Peter, Shereen Tadros, Melissa Hill , et al. · 2024

Gaps in genomics knowledge and drivers in confidence have been identified herein, highlighting the need for improvements in undergraduate genomics education to prepare future doctors to confidently practise in the genomics era.

38 Reducing noise levels in the neonatal intensive care unit: a quality improvement project Open

M.L. Vozza, Eilis Scully, Cristine Sortica da Costa · 2023

Background Noise in the Neonatal Intensive Care Unit (NICU) can significantly impact on the neurodevelopment of both term and preterm infants. Excessive sound stimuli may cause abnormal brain and sensory development in preterm infants, as …

Near-infrared spectroscopy monitoring of neonatal cerebrovascular reactivity: where are we now? Open

Silvia Martini, Liesbeth Thewissen, Topun Austin, Cristine Sortica da Costa, Willem P. de Boode , et al. · 2023

1173 Application of high-resolution physiological data in necrotizing enterocolitis management: a literature review Open

Sierra Schaffer, Simon Eaton, Cristine Sortica da Costa · 2022

Aims Necrotizing enterocolitis (NEC) is a serious condition with high morbidity and mortality that is most common in premature neonates. As survival rates of premature births are rising overall, so is the prevalence of NEC. Its pathophysio…

1099 Exploring the Environmental Impact of Inhaled Nitric Oxide Used in Neonatal Units Open

Zoe Porteous, Emilie Seager, Cristine Sortica da Costa · 2022

Aims Inhaled nitric oxide (iNO) is commonly used for the treatment of persistent pulmonary hypertension (PPHN). It is common practice to commence the treatment at 20ppm and the treatment can last several days. However what environmental im…

Post-haemorrhagic hydrocephalus is associated with poorer surgical and neurodevelopmental sequelae than other causes of infant hydrocephalus Open

Malak Mohamed, Saniya Mediratta, Ajai Chari, Cristine Sortica da Costa, Greg James , et al. · 2021

128 Inspiring the future generation in paediatrics during the pandemic – great ormond street hospital summer school 2020 Open

Shuang Liu, Jonathan H. Smith, Abbie Tutt, Justin Poisson, Spiros Blackburn , et al. · 2020

Introduction Great Ormond Street Hospital (GOSH) Summer School aims to inspire medical students and junior doctors to follow a career in Paediatrics, especially given the low competition ratio in Paediatrics training applications in the la…

8 Great Ormond Street Hospital (GOSH) Summer School 2020: lessons on designing a digital conference Open

Shuang Liu, Jonathan G. Smith, Abbie Tutt, Justin Poisson, Spiros Blackburn , et al. · 2020

Background GOSH Summer School (GSS) is a conference for medical students and early career trainees. It has been run as a face-to-face event in the previous two years. COVID-19 outbreak challenged us to reformat the conference digitally. Me…

130 Inspiring the future generation in Paediatrics during the pandemic – Great Ormond Street Hospital Summer School 2020 Open

Shuang Liu, Jonathan H. Smith, Abbie Tutt, Justin Poisson, Spiros Blackburn , et al. · 2020

Introduction Great Ormond Street Hospital (GOSH) Summer School aims to inspire medical students and junior doctors to follow a career in Paediatrics, especially given the low competition ratio in Paediatrics training applications in the la…

91 Great ormond street hospital SUMMER SCHOOL 2020 – embracing the #digitallife in conferencing Open

Abbie Tutt, Shuang Liu, Jonathan H. Smith, Justin Poisson, Spiros Blackburn , et al. · 2020

Background Social Media is an accompanying staple to conferences but also allows attendees who are attending virtually to interact with the day. GOSH Summer School (GSS) is normally run as a face to face event but had to be moved to a virt…

Changes in hemodynamics, cerebral oxygenation and cerebrovascular reactivity during the early transitional circulation in preterm infants Open

Cristine Sortica da Costa, Danilo Cardim, Zoltán Molnár, Wilf Kelsall, Isabel Ng , et al. · 2019

Neonatal cerebrovascular autoregulation Open

Christopher J. Rhee, Cristine Sortica da Costa, Topun Austin, Ken M. Brady, Marek Czosnyka , et al. · 2018

Pneumoperitoneum in a neonate weighing less than 500 g. What do we really know about it? Open

Audrienne Sammut, Miguel Soares Oliveira, Claire Jackson, Cristine Sortica da Costa · 2018

Pneumoperitoneum in preterm infants is a surgical emergency as it is usually indicative of intestinal perforation. Rare cases of idiopathic pneumoperitoneum have been described in the literature, the underlying causes and pathophysiology o…

Monitoring of cerebral oxygenation, cerebrovascular reactivity and circulatory function in preterm infants Open

Cristine Sortica da Costa · 2018

Monitoring of cerebral oxygenation, cerebrovascular reactivity and circulatory function in preterm infants Brain injury in the preterm infant is associated with death and lifelong disability. Cerebral hypoxia and fluctuations in cerebral b…

Complexity of brain signals is associated with outcome in preterm infants Open

Cristine Sortica da Costa, Michał M. Placek, Marek Czosnyka, Brenno Cabella, Magdalena Kasprowicz , et al. · 2017

A characteristic feature of complex healthy biological systems is the ability to react and adapt to minute changes in the environment. This ‘complexity’ manifests itself in highly irregular patterns of various physiological measurements. H…

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