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View article: Cross-border investigation of a tuberculosis outbreak in Vienna linked to a multi-country cluster among foreign-born individuals, Europe, 2021 to 2025
Cross-border investigation of a tuberculosis outbreak in Vienna linked to a multi-country cluster among foreign-born individuals, Europe, 2021 to 2025 Open
Collaborative genomic and epidemiological investigations identified a tuberculosis outbreak in Vienna as part of a multi-country cluster comprising 57 foreign-born cases of Mycobacterium tuberculosis ST215/Beijing 2.2.1 notified 2021–2025.…
View article: Antimicrobial resistance in Neisseria gonorrhoeae and its risk groups in 23 European countries in 2022 within the European Gonococcal Antimicrobial Surveillance Programme (Euro-GASP): a retrospective observational study
Antimicrobial resistance in Neisseria gonorrhoeae and its risk groups in 23 European countries in 2022 within the European Gonococcal Antimicrobial Surveillance Programme (Euro-GASP): a retrospective observational study Open
ECDC.
View article: Increase in tuberculosis among children and young adolescents, European Union/European Economic Area, 2015 to 2023
Increase in tuberculosis among children and young adolescents, European Union/European Economic Area, 2015 to 2023 Open
As tuberculosis (TB) in children is an indicator of ongoing transmission, we analysed surveillance data to understand the increase in notified TB cases among individuals aged < 15 years in the European Union/European Economic Area countrie…
View article: Shifting tuberculosis dynamics in the EU/EEA: geographical and drug resistance trends among people of foreign origin, 2019 to 2023
Shifting tuberculosis dynamics in the EU/EEA: geographical and drug resistance trends among people of foreign origin, 2019 to 2023 Open
We observed shifting trends in tuberculosis (TB) epidemiology in the EU/EEA between 2019 and 2023. In 2023, TB notifications among people of foreign origin increased by 24.6% after decreasing between 2019 and 2020. The majority originated …
View article: Characteristic SNPs defining the major multidrug-resistant Mycobacterium tuberculosis clusters identified by EuSeqMyTB to support routine surveillance, EU/EEA, 2017 to 2019
Characteristic SNPs defining the major multidrug-resistant Mycobacterium tuberculosis clusters identified by EuSeqMyTB to support routine surveillance, EU/EEA, 2017 to 2019 Open
Background The EUSeqMyTB project, conducted in 2020, used whole genome sequencing (WGS) for surveillance of drug-resistant Mycobacterium tuberculosis in the European Union/European Economic Area (EU/EEA) and identified 56 internationally c…
View article: Tuberculosis in people of Ukrainian origin in the European Union and the European Economic Area, 2019 to 2022
Tuberculosis in people of Ukrainian origin in the European Union and the European Economic Area, 2019 to 2022 Open
Approximately five million Ukrainians were displaced to the EU/EEA following the Russian invasion of Ukraine. While tuberculosis (TB) notification rates per 100,000 Ukrainians in the EU/EEA remained stable, the number of notified TB cases …
View article: High tetracycline resistance percentages in Neisseria gonorrhoeae in Europe: is doxycycline post-exposure prophylaxis unlikely to reduce the incident gonorrhoea cases?
High tetracycline resistance percentages in Neisseria gonorrhoeae in Europe: is doxycycline post-exposure prophylaxis unlikely to reduce the incident gonorrhoea cases? Open
View article: Monitoring the progress achieved towards ending tuberculosis in the European Union/European Economic Area, 2018 to 2021
Monitoring the progress achieved towards ending tuberculosis in the European Union/European Economic Area, 2018 to 2021 Open
We report progress in the European Union/European Economic Area (EU/EEA) towards the Sustainable Development Goal target for tuberculosis (TB) and for the associated global/regional targets. The TB notification rate and the number of TB de…
View article: Experiences from 4 Years of Organization of an External Quality Assessment for Mycobacterium tuberculosis Whole-Genome Sequencing in the European Union/European Economic Area
Experiences from 4 Years of Organization of an External Quality Assessment for Mycobacterium tuberculosis Whole-Genome Sequencing in the European Union/European Economic Area Open
The wider availability of whole-genome sequencing (WGS) coupled to new developments in bioinformatic tools and databases to interpret Mycobacterium tuberculosis complex WGS data has accelerated the adoption of this method for the routine p…
View article: Influenza returns with a season dominated by clade 3C.2a1b.2a.2 A(H3N2) viruses, WHO European Region, 2021/22
Influenza returns with a season dominated by clade 3C.2a1b.2a.2 A(H3N2) viruses, WHO European Region, 2021/22 Open
In the WHO European Region, COVID-19 non-pharmaceutical interventions continued slowing influenza circulation in the 2021/22 season, with reduced characterisation data. A(H3) predominated and, in some countries, co-circulated with A(H1)pdm…
View article: Current state of national TB laboratory networks in Europe: achievements and challenges
Current state of national TB laboratory networks in Europe: achievements and challenges Open
View article: Circulation of pertussis and poor protection against diphtheria among middle-aged adults in 18 European countries
Circulation of pertussis and poor protection against diphtheria among middle-aged adults in 18 European countries Open
View article: Limited Capability for Testing <i>Mycobacterium tuberculosis</i> for Susceptibility to New Drugs
Limited Capability for Testing <i>Mycobacterium tuberculosis</i> for Susceptibility to New Drugs Open
We surveyed availability of phenotypic drug susceptibility testing for drug-resistant Mycobacterium tuberculosis in Europe. Of 27 laboratories, 17 tested for linezolid, 11 for clofazimine, 9 for bedaquiline, and 6 for delamanid during 2019…
View article: Reporting of interferon-gamma release assay results close to cut-off values
Reporting of interferon-gamma release assay results close to cut-off values Open
View article: Impact of the COVID-19 pandemic on tuberculosis laboratory services in Europe
Impact of the COVID-19 pandemic on tuberculosis laboratory services in Europe Open
Sustainable support from healthcare bodies is needed to preserve TB laboratory capacity, and maintain personnel and skills, to minimise negative effects of the COVID-19 pandemic on laboratory services severely disrupted in the early months…
View article: Use of a whole genome sequencing-based approach for<i>Mycobacterium tuberculosis</i>surveillance in Europe in 2017–2019: an ECDC pilot study
Use of a whole genome sequencing-based approach for<i>Mycobacterium tuberculosis</i>surveillance in Europe in 2017–2019: an ECDC pilot study Open
Whole genome sequencing (WGS) can be used for molecular typing and characterisation of Mycobacterium tuberculosis complex (MTBC) strains. We evaluated the systematic use of a WGS-based approach for MTBC surveillance involving all European …
View article: Widespread circulation of pertussis and poor protection against diphtheria among middle-aged adults in 18 European countries
Widespread circulation of pertussis and poor protection against diphtheria among middle-aged adults in 18 European countries Open
Reported incidence of pertussis in member states of the European Union (EU) and the European Economic Area (EEA) varies and may not reflect the real situation. In the EU/EEA, vaccine-induced protection against diphtheria and tetanus seems …
View article: Epidemic and pandemic viral infections: impact on tuberculosis and the lung
Epidemic and pandemic viral infections: impact on tuberculosis and the lung Open
Major epidemics, including some that qualify as pandemics, such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), HIV, influenza A (H1N1)pdm/09 and most recently COVID-19, affect the lung. Tuberculosis (…
View article: European Union training programme for tuberculosis laboratory experts: design, contribution and future direction
European Union training programme for tuberculosis laboratory experts: design, contribution and future direction Open
View article: Completeness of tuberculosis (TB) notification: inventory studies and capture-recapture analyses, six European Union countries, 2014 to 2016
Completeness of tuberculosis (TB) notification: inventory studies and capture-recapture analyses, six European Union countries, 2014 to 2016 Open
Background Progress towards the World Health Organization’s End TB Strategy is monitored by assessing tuberculosis (TB) incidence, often derived from TB notification, assuming complete case detection and reporting. This assumption is unlik…
View article: Tuberculosis surveillance in adolescents: what to learn from European Union/European Economic Area data?
Tuberculosis surveillance in adolescents: what to learn from European Union/European Economic Area data? Open
OBJECTIVE: To describe tuberculosis (TB) characteristics in the adolescent 10–19 years age group that is often underrepresented in surveillance and studies despite the high global TB burden estimated for this group. SETTING AND DESIGN: We …
View article: Completeness of tuberculosis (TB) notification: inventory studies and capture-recapture analyses, six European Union countries, 2014 to 2016
Completeness of tuberculosis (TB) notification: inventory studies and capture-recapture analyses, six European Union countries, 2014 to 2016 Open
Background: Progress towards the World Health Organization’s End TB Strategy is monitored by assessing tuberculosis (TB) incidence, often derived from TB notification, assuming complete case detection and reporting. This assumption is unli…
View article: Whole-Genome Sequencing as Tool for Investigating International Tuberculosis Outbreaks: A Systematic Review
Whole-Genome Sequencing as Tool for Investigating International Tuberculosis Outbreaks: A Systematic Review Open
Background: Whole-genome sequencing (WGS) can support the investigation of tuberculosis (TB) outbreaks. The technique has been applied to estimate the timing and directionality of transmission and to exclude cases from an investigat…
View article: Improvement in serological diagnosis of pertussis by external quality assessment
Improvement in serological diagnosis of pertussis by external quality assessment Open
Purpose. Serological analysis is an essential tool for the diagnosis of pertussis or whooping cough, disease surveillance and the evaluation of vaccine effectiveness against Bordetella pertussis . Accurate measurement of anti-pertussis tox…
View article: Will we reach the Sustainable Development Goals target for tuberculosis in the European Union/European Economic Area by 2030?
Will we reach the Sustainable Development Goals target for tuberculosis in the European Union/European Economic Area by 2030? Open
We assessed progress towards the Sustainable Development Goals target for tuberculosis in the European Union/European Economic Area using the latest tuberculosis (TB) surveillance and Eurostat data. Both the TB notification rate and the nu…
View article: Isoniazid (INH) mono-resistance and tuberculosis (TB) treatment success: analysis of European surveillance data, 2002 to 2014
Isoniazid (INH) mono-resistance and tuberculosis (TB) treatment success: analysis of European surveillance data, 2002 to 2014 Open
Introduction: Isoniazid (INH) is an essential drug for tuberculosis (TB) treatment. Resistance to INH may increase the likelihood of negative treatment outcome. Aim: We aimed to determine the impact of INH mono-resistance on TB treatment o…
View article: Molecular and genomic typing for tuberculosis surveillance: A survey study in 26 European countries
Molecular and genomic typing for tuberculosis surveillance: A survey study in 26 European countries Open
Our study shows a wide use of molecular and genomic typing data for TB surveillance in EU/EEA countries and reveals that transition to WGS-based typing is ongoing or is considered in most countries. However, our results also show a high he…
View article: Molecular and genomic typing for tuberculosis surveillance: a survey study in 26 European countries
Molecular and genomic typing for tuberculosis surveillance: a survey study in 26 European countries Open
Molecular typing and whole genome sequencing (WGS) information is used for (inter-) national outbreak investigations. To assist the implementation of these techniques for tuberculosis (TB) surveillance and outbreak investigations at Europe…
View article: Time-and-motion tool for the assessment of working time in tuberculosis laboratories: a multicentre study
Time-and-motion tool for the assessment of working time in tuberculosis laboratories: a multicentre study Open
The T&M tool can be considered a universal and objective methodology contributing to workload assessment in TB diagnostic laboratories. Comparison of workload between laboratories could help laboratory managers justify their resource and p…
View article: EUSeqMyTB to set standards and build capacity for whole genome sequencing for tuberculosis in the EU
EUSeqMyTB to set standards and build capacity for whole genome sequencing for tuberculosis in the EU Open