Cuie Cheng
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View article: Development and validation of a diagnostic and screening method for gastric cancer by combining new gastric cancer screening score and serum biomarkers: a prospective study
Development and validation of a diagnostic and screening method for gastric cancer by combining new gastric cancer screening score and serum biomarkers: a prospective study Open
The new model system based on NGCSS combined with multiple tumor markers is feasible and exhibits improved diagnostic performance. The conclusions of this study require further validation and elaboration through large-sample multicenter fo…
View article: Profiling of circulating T follicular helper and T peripheral helper cell subsets in patients with primary biliary cholangitis
Profiling of circulating T follicular helper and T peripheral helper cell subsets in patients with primary biliary cholangitis Open
Primary biliary cholangitis (PBC) is a common chronic cholestatic autoimmune liver disease that may progress to liver fibrosis or cirrhosis if not accurately diagnosed and promptly treated. T follicular helper (Tfh) cells and T peripheral …
View article: Risk Factor Analysis of Hidden Blood Loss in Unilateral Biportal Endoscopy for Degenerative Lumbar Diseases
Risk Factor Analysis of Hidden Blood Loss in Unilateral Biportal Endoscopy for Degenerative Lumbar Diseases Open
Background To explore the risk factors associated with hidden blood loss (HBL) during unilateral biportal endoscopy (UBE) for degenerative lumbar diseases, this study provides a theoretical foundation for the precise prevention and managem…
View article: Circulating Neutrophil Extracellular Traps as Diagnostic and Prognostic Markers for Inflammatory Bowel Disease: A Case-Control Study
Circulating Neutrophil Extracellular Traps as Diagnostic and Prognostic Markers for Inflammatory Bowel Disease: A Case-Control Study Open
These findings suggest that NETs biomarkers may serve as effective diagnostic and prognostic tools for IBD, enabling early intervention and improved long-term management.
View article: Long noncoding RNA <i>SNHG5</i> promotes 5-fluorouracil resistance in colorectal cancer by regulating miR-26b/p-glycoprotein axis
Long noncoding RNA <i>SNHG5</i> promotes 5-fluorouracil resistance in colorectal cancer by regulating miR-26b/p-glycoprotein axis Open
BACKGROUND Colorectal cancer (CRC) is the second most prevalent cause of cancer-related mortality and is increasing in younger individuals. Chemotherapy, a crucial adjuvant systemic therapy for CRC management, often leads to resistance thr…
View article: AI-powered genomic mutation signature for predicting immune checkpoint inhibitor therapy outcomes in gastroesophageal cancer: a multi-cohort analysis
AI-powered genomic mutation signature for predicting immune checkpoint inhibitor therapy outcomes in gastroesophageal cancer: a multi-cohort analysis Open
The GMS utilized in this study successfully demonstrated the ability to reliably predict the survival advantage for patients with GECs undergoing ICI therapy.
View article: A machine learning model for predicting acute kidney injury secondary to severe acute pancreatitis
A machine learning model for predicting acute kidney injury secondary to severe acute pancreatitis Open
To the Editor: Severe acute pancreatitis (SAP) is a common critical disease in gastroenterology, and 69.3% of patients have acute kidney injury (AKI).[1] Early diagnosis and treatment are very important in improving the prognosis of these …
View article: Analysis of white-light imaging-based features predictive for determination of lesion depths of superficial flat esophageal squamous cell carcinoma: a retrospective multicenter study from China
Analysis of white-light imaging-based features predictive for determination of lesion depths of superficial flat esophageal squamous cell carcinoma: a retrospective multicenter study from China Open
Objectives Endoscopic diagnosis of invasion depth of superficial esophageal squamous cell carcinoma (SESCC) by white-light imaging (WLI) modality remains difficult. This study aims to clarify WLI-based features which are predictive for inv…
View article: Study protocol for artificial intelligence-assisted sponge cytology as pre-endoscopy screening for early esophegeal squmaous epithelial lesions in China
Study protocol for artificial intelligence-assisted sponge cytology as pre-endoscopy screening for early esophegeal squmaous epithelial lesions in China Open
Background Endoscopic screening is the widely accepted screening strategy for esophageal squmaous cell carcinoma (ESCC). However, massive endoscopic screening is expensive and not cost-efficient, and novel pre-endoscopy detection used as a…
View article: Expression profile, clinical significance and biological functions of IGF2BP2 in esophageal squamous cell carcinoma
Expression profile, clinical significance and biological functions of IGF2BP2 in esophageal squamous cell carcinoma Open
The ectopic expression of insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) has been demonstrated to facilitate tumorigenesis and induce proliferation in a various types of cancer. However, the role of IGF2BP2 in esophageal squ…
View article: MiR-26b regulates 5-FU-resistance in human colorectal cancer via down-regulation of Pgp.
MiR-26b regulates 5-FU-resistance in human colorectal cancer via down-regulation of Pgp. Open
Chemotherapy resistance frequently drives tumor progression. However, the underlying molecular mechanisms remain unclear. In this study, we found that the expression level of miR-26b was down-regulated in the human colorectal cancer tissue…