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View article: Unlocking the genetic secrets of Dorper sheep: insights into wool shedding and hair follicle development
Unlocking the genetic secrets of Dorper sheep: insights into wool shedding and hair follicle development Open
Dorper sheep is popular among farming enterprises with strong adaptability, disease resistance, and roughage tolerance, and an unique characteristic of natural shedding of wool. In a large number of observations on experimental sheep farms…
View article: SGK1 promotes the lipid accumulation via regulating the transcriptional activity of FOXO1 in bovine
SGK1 promotes the lipid accumulation via regulating the transcriptional activity of FOXO1 in bovine Open
SGK1 is a required epigenetic regulatory factor for bovine preadipocyte proliferation and differentiation, which contributes to a better understanding of fat deposition and meat quality improvement in cattle.
View article: Proteomic and metabolomic analysis of ageing beef exudate to determine that iron metabolism enhances muscle protein and lipid oxidation
Proteomic and metabolomic analysis of ageing beef exudate to determine that iron metabolism enhances muscle protein and lipid oxidation Open
The study aimed to assess differences in proteomic and metabolite profiles in ageing (1, 2, 4, and 6 days at 4 °C) beef exudates and determine their relationship with beef muscle iron metabolism and oxidation. Proteomic and metabolomic ana…
View article: Construction of a molecular regulatory network related to fat deposition by multi-tissue transcriptome sequencing of Jiaxian red cattle
Construction of a molecular regulatory network related to fat deposition by multi-tissue transcriptome sequencing of Jiaxian red cattle Open
Intramuscular fat (IMF) refers to the fat that accumulates between muscle bundles or within muscle cells, whose content significantly impacts the taste, tenderness, and flavor of meat products, making it a crucial economic characteristic i…
View article: Characterization of feed efficiency-related key signatures molecular in different cattle breeds
Characterization of feed efficiency-related key signatures molecular in different cattle breeds Open
Feed efficiency is a major constraint in the beef industry and has a significant negative correlation with residual feed intake (RFI). RFI is widely used as a measure of feed efficiency in beef cattle and is independent of economic traits …
View article: Peer Review #2 of "Identification of key genes in bovine muscle development by co-expression analysis (v0.1)"
Peer Review #2 of "Identification of key genes in bovine muscle development by co-expression analysis (v0.1)" Open
Background: Skeletal muscle is not only an important tissue involved in exercise and metabolism, but also an important part of livestock and poultry meat products.Its growth and development determines the output and quality of meat to a ce…
View article: Identification of key genes in bovine muscle development by co-expression analysis
Identification of key genes in bovine muscle development by co-expression analysis Open
Background Skeletal muscle is not only an important tissue involved in exercise and metabolism, but also an important part of livestock and poultry meat products. Its growth and development determines the output and quality of meat to a ce…
View article: Genome-Wide Identification and Characterization of Bovine Fibroblast Growth Factor (FGF) Gene and Its Expression during Adipocyte Differentiation
Genome-Wide Identification and Characterization of Bovine Fibroblast Growth Factor (FGF) Gene and Its Expression during Adipocyte Differentiation Open
Fibroblast growth factor (FGF) family genes are a class of polypeptide factors with similar structures that play an important role in regulating cell proliferation and differentiation, nutritional metabolism, and neural activity. In previo…
View article: SGK1 affects bovine adipocyte proliferation and differentiation via regulation of the PI3K/Akt signaling pathway
SGK1 affects bovine adipocyte proliferation and differentiation via regulation of the PI3K/Akt signaling pathway Open
Objectives: Serum/glucocorticoid-inducible kinase 1 ( SGK1 ) gene encodes a serine/threonine protein kinase that plays an essential role in cellular stress response and regulation of multiple metabolic processes. However, its role in bovin…
View article: Genome-wide identification of the jumonji C domain- containing histone demethylase gene family in wheat and their expression analysis under drought stress
Genome-wide identification of the jumonji C domain- containing histone demethylase gene family in wheat and their expression analysis under drought stress Open
Methylation and demethylation of histone play a crucial role in regulating chromatin formation and gene expression. The jumonji C (JmjC) domain-containing proteins are demethylases that are involved in regulating epigenetic modification in…
View article: Weighted Gene Co-Expression Network Analysis Identifies Key Modules and Central Genes Associated With Bovine Subcutaneous Adipose Tissue
Weighted Gene Co-Expression Network Analysis Identifies Key Modules and Central Genes Associated With Bovine Subcutaneous Adipose Tissue Open
Background Fat deposition is an important economic trait in livestock and poultry production. However, the relationship between various genes and signal pathways of fat deposition is still unclear to a large extent. The purpose of this stu…
View article: Identification of Key Genes Associated With Early Calf-Hood Nutrition in Subcutaneous and Visceral Adipose Tissues by Co-Expression Analysis
Identification of Key Genes Associated With Early Calf-Hood Nutrition in Subcutaneous and Visceral Adipose Tissues by Co-Expression Analysis Open
Background Substantive evidence has confirmed that nutrition state is associated with health risk and the onset of pubertal and metabolic profile. Due to heterogeneity, adipose tissues in different anatomical positions tend to show various…
View article: Identification of 5P Chromosomes in Wheat-Agropyron cristatum Addition Line and Analysis of Its Effect on Homologous Pairing of Wheat Chromosomes
Identification of 5P Chromosomes in Wheat-Agropyron cristatum Addition Line and Analysis of Its Effect on Homologous Pairing of Wheat Chromosomes Open
As an important wheat wild relative, the P genome of Agropyron cristatum (L.) Gaertn. (2 n = 4 x = 28) is very valuable for wheat improvement. A complete set of wheat- A. cristatum disomic addition lines is the basis for studying the genet…
View article: Identifying Key Genes and Functionally Enriched Pathways of Diverse Adipose Tissue Types in Cattle
Identifying Key Genes and Functionally Enriched Pathways of Diverse Adipose Tissue Types in Cattle Open
Background: Fat is a tissue that not just stores energy and plays a protective role; it is also a vital endocrine organ that generates and integrates signals to influence metabolism. Meanwhile, the excessive accumulation of lipids in adipo…
View article: SGK1 Affects the Phosphorylation of FOXO1/FOXO3 Promoting Bovine Fat Deposition via the PI3K/Akt Signaling Pathway
SGK1 Affects the Phosphorylation of FOXO1/FOXO3 Promoting Bovine Fat Deposition via the PI3K/Akt Signaling Pathway Open
Background : Improving the intramuscular fat content of beef not only could improve our living standard, but decrease the the risk of the disease from the aspect of human nutrition and diet. Serum/glucocorticoid-inducible kinase 1 (SGK1) i…
View article: Identification of key genes and functional enrichment pathways involved in fat deposition in Xinyang buffalo by WGCNA
Identification of key genes and functional enrichment pathways involved in fat deposition in Xinyang buffalo by WGCNA Open
The Xinyang buffalo is a valuable and endangered domestic heritage resource in the Dabie Mountain region in China. With the increasing mechanization of agriculture, the Xinyang buffalo, mainly used for labor, faces unprecedented challenges…
View article: Identification of core genes affecting IMF deposition in bovine
Identification of core genes affecting IMF deposition in bovine Open
Intramuscular fat (IMF) content is an important economic factor in beef production. However, knowledge on the key factors controlling bovine IMF is limited. In this study, using weighted gene co-expression network analysis (WGCNA), nine mo…
View article: TMT Quantitative Proteomics Analysis Reveals the Effects of Transport Stress on Iron Metabolism in the Liver of Chicken
TMT Quantitative Proteomics Analysis Reveals the Effects of Transport Stress on Iron Metabolism in the Liver of Chicken Open
Abnormal iron metabolism can cause oxidative stress in broilers, and transport stress (TS) may potentially influence iron metabolism. However, the mechanisms by which TS affects iron metabolism are unclear. This study used quantitative pro…
View article: Identification and Functional Verification Reveals that miR-195 Inhibiting THRSP to Affect Fat Deposition in Xinyang Buffalo
Identification and Functional Verification Reveals that miR-195 Inhibiting THRSP to Affect Fat Deposition in Xinyang Buffalo Open
The buffalo population is extensive in China, but its meat quality is relatively inferior. Therefore, improving meat quality should be one of the breeding goals. microRNAs (miRNAs) play an essential regulatory role in the post-transcriptio…
View article: Genome-Wide Identification and Expression Profiling Analysis of Wnt Family Genes Affecting Adipocyte Differentiation in Cattle
Genome-Wide Identification and Expression Profiling Analysis of Wnt Family Genes Affecting Adipocyte Differentiation in Cattle Open
Wnt is a family of conserved glycoproteins that functions in a variety of crucial biological processes including tissue regeneration, animal development, and cell proliferation and differentiation. For its functional diversity and importan…
View article: Additional file 9 of Genome-wide identification of cyclin-dependent kinase (CDK) genes affecting adipocyte differentiation in cattle
Additional file 9 of Genome-wide identification of cyclin-dependent kinase (CDK) genes affecting adipocyte differentiation in cattle Open
Additional file 9. Primers sequences of 25 bovine CDK genes.
View article: Additional file 8 of Genome-wide identification of cyclin-dependent kinase (CDK) genes affecting adipocyte differentiation in cattle
Additional file 8 of Genome-wide identification of cyclin-dependent kinase (CDK) genes affecting adipocyte differentiation in cattle Open
Additional file 8. Expression values (RPKM) of 163 bovine samples in 60 tissue types.
View article: Additional file 1 of Genome-wide identification of cyclin-dependent kinase (CDK) genes affecting adipocyte differentiation in cattle
Additional file 1 of Genome-wide identification of cyclin-dependent kinase (CDK) genes affecting adipocyte differentiation in cattle Open
Additional file 1. Genome-wide identified CDK family members in Bovidae.
View article: Additional file 2 of Genome-wide identification of cyclin-dependent kinase (CDK) genes affecting adipocyte differentiation in cattle
Additional file 2 of Genome-wide identification of cyclin-dependent kinase (CDK) genes affecting adipocyte differentiation in cattle Open
Additional file 2. Protein sequences of CDK family members in ten species.
View article: Genome-Wide Identification of Cyclin Dependent Kinase (CDK) Family Genes Influencing Adipocyte Differentiation in Cattle
Genome-Wide Identification of Cyclin Dependent Kinase (CDK) Family Genes Influencing Adipocyte Differentiation in Cattle Open
Background: The cyclin dependent kinases (CDKs) are protein kinases regulating important cellular processes such as cell cycle and transcription. A variety of studies have shown that many CDK genes also played a critical role during adipog…
View article: Chromosomal localization of genes conferring desirable agronomic traits from Agropyron cristatum chromosome 1P
Chromosomal localization of genes conferring desirable agronomic traits from Agropyron cristatum chromosome 1P Open
Agropyron cristatum (L.) Gaertn. (2n = 4x = 28, PPPP), a wild relative of common wheat, possesses many potentially valuable genes for wheat breeding. To transfer these genes into wheat, a series of wheat-A. cristatum derivatives have been …
View article: Chromosomal Localization of Genes Conferring Desirable Agronomic Traits from Wheat-Agropyron cristatum Disomic Addition Line 5113
Chromosomal Localization of Genes Conferring Desirable Agronomic Traits from Wheat-Agropyron cristatum Disomic Addition Line 5113 Open
Creation of wheat-alien disomic addition lines and localization of desirable genes on alien chromosomes are important for utilization of these genes in genetic improvement of common wheat. In this study, wheat-Agropyron cristatum derivativ…