Cuilin Zhang
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View article: Plasma metabolomic signature of breastfeeding and risk of cardiometabolic diseases
Plasma metabolomic signature of breastfeeding and risk of cardiometabolic diseases Open
Breastfeeding is inversely associated with cardiometabolic disease incidence in prospective studies; however, the metabolic pathways underlying these associations remain largely unknown. Here, we derive a plasma metabolomic score of lifeti…
View article: Inflammatory and Insulinemic Dietary Patterns and Risk of Type 2 Diabetes Among Women With a History of Gestational Diabetes Mellitus: A Prospective Study of 84,174 Person-Years of Follow-up
Inflammatory and Insulinemic Dietary Patterns and Risk of Type 2 Diabetes Among Women With a History of Gestational Diabetes Mellitus: A Prospective Study of 84,174 Person-Years of Follow-up Open
OBJECTIVE We examined the associations of inflammatory and insulinemic diets with type 2 diabetes (T2D) risk among women with a history of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS We followed 4,318 women with a hist…
View article: Planetary Health Diet and Risk of Cardiometabolic Diseases Among Women With Gestational Diabetes
Planetary Health Diet and Risk of Cardiometabolic Diseases Among Women With Gestational Diabetes Open
Importance The Planetary Health Diet (PHD) integrates health and environmental sustainability, yet its association with chronic disease outcomes remains underexplored, particularly among women with a history of gestational diabetes (GD), w…
View article: Low-Carbohydrate Diets of Varying Macronutrient Quality and Risk of Type 2 Diabetes in Three U.S. Prospective Cohort Studies
Low-Carbohydrate Diets of Varying Macronutrient Quality and Risk of Type 2 Diabetes in Three U.S. Prospective Cohort Studies Open
Objective: To prospectively examine associations between five low-carbohydrate diets (LCDs), differentiated by macronutrient quality, and type 2 diabetes (T2D) risk.Research Design and Methods: This cohort study included 199,006 U.S. adult…
View article: Low-Carbohydrate Diets of Varying Macronutrient Quality and Risk of Type 2 Diabetes in Three U.S. Prospective Cohort Studies
Low-Carbohydrate Diets of Varying Macronutrient Quality and Risk of Type 2 Diabetes in Three U.S. Prospective Cohort Studies Open
Objective: To prospectively examine associations between five low-carbohydrate diets (LCDs), differentiated by macronutrient quality, and type 2 diabetes (T2D) risk.Research Design and Methods: This cohort study included 199,006 U.S. adult…
View article: Postpartum Weight Retention and Mortality Over 50 Years of Follow-up
Postpartum Weight Retention and Mortality Over 50 Years of Follow-up Open
Objective: This study aimed to evaluate the link between postpartum weight retention (PPWR) and long-term mortality. Methods: In this secondary analysis of 8165 women with ≥2 pregnancies in the Collaborative Perinatal Project (U.S., 1959–1…
View article: Supplementary Table S1 from History of Breastfeeding in Relation to Circulating Inflammatory and Metabolic Biomarkers
Supplementary Table S1 from History of Breastfeeding in Relation to Circulating Inflammatory and Metabolic Biomarkers Open
List of nested case-control studies included in this study
View article: Supplementary Table S4 from History of Breastfeeding in Relation to Circulating Inflammatory and Metabolic Biomarkers
Supplementary Table S4 from History of Breastfeeding in Relation to Circulating Inflammatory and Metabolic Biomarkers Open
Inflammatory biomarker associations stratified by BMI at blood draw
View article: Supplementary Table S2 from History of Breastfeeding in Relation to Circulating Inflammatory and Metabolic Biomarkers
Supplementary Table S2 from History of Breastfeeding in Relation to Circulating Inflammatory and Metabolic Biomarkers Open
Details of the assays
View article: Data from History of Breastfeeding in Relation to Circulating Inflammatory and Metabolic Biomarkers
Data from History of Breastfeeding in Relation to Circulating Inflammatory and Metabolic Biomarkers Open
Background:Breastfeeding history has been associated with reduced risk of chronic diseases, although the underlying biological link is unclear.Methods:The study included 16,165 parous women in the Nurses’ Health Studies who reported lactat…
View article: Supplementary Table S5 from History of Breastfeeding in Relation to Circulating Inflammatory and Metabolic Biomarkers
Supplementary Table S5 from History of Breastfeeding in Relation to Circulating Inflammatory and Metabolic Biomarkers Open
Metabolic biomarker associations stratified by menopausal status
View article: Supplementary Table S6 from History of Breastfeeding in Relation to Circulating Inflammatory and Metabolic Biomarkers
Supplementary Table S6 from History of Breastfeeding in Relation to Circulating Inflammatory and Metabolic Biomarkers Open
Metabolic biomarker associations stratified by BMI at blood draw
View article: Supplementary Table S3 from History of Breastfeeding in Relation to Circulating Inflammatory and Metabolic Biomarkers
Supplementary Table S3 from History of Breastfeeding in Relation to Circulating Inflammatory and Metabolic Biomarkers Open
Inflammatory biomarker associations stratified analysis by menopausal status
View article: Maternal Adherence to Healthy Dietary Patterns During Pregnancy and Gestational Weight Gain
Maternal Adherence to Healthy Dietary Patterns During Pregnancy and Gestational Weight Gain Open
Background/Objectives: Suboptimal gestational weight gain (GWG) has been linked to increased risks of adverse maternal outcomes. Evidence linking diet in pregnancy to GWG remains limited. We assessed relationships between adherence to five…
View article: Ultra-processed foods and diet quality in association with long-term weight change and progression to type 2 diabetes among individuals with a history of gestational diabetes mellitus – a prospective study
Ultra-processed foods and diet quality in association with long-term weight change and progression to type 2 diabetes among individuals with a history of gestational diabetes mellitus – a prospective study Open
Objective We examined the associations of overall and group-specific ultra-processed food (UPF) consumption with long-term weight change and T2D progression following gestational diabetes mellitus (GDM)-complicated pregnancies. Research De…
View article: Ultra-processed foods and diet quality in association with long-term weight change and progression to type 2 diabetes among individuals with a history of gestational diabetes mellitus – a prospective study
Ultra-processed foods and diet quality in association with long-term weight change and progression to type 2 diabetes among individuals with a history of gestational diabetes mellitus – a prospective study Open
Objective We examined the associations of overall and group-specific ultra-processed food (UPF) consumption with long-term weight change and T2D progression following gestational diabetes mellitus (GDM)-complicated pregnancies. Research De…
View article: Long‐Term Adherence to Modifiable Factors and Incident Cardiovascular Disease Among Women With a History of Gestational Diabetes: A Prospective Cohort Study
Long‐Term Adherence to Modifiable Factors and Incident Cardiovascular Disease Among Women With a History of Gestational Diabetes: A Prospective Cohort Study Open
Background Women with prior gestational diabetes are at increased risk of cardiovascular disease (CVD), but whether and to what extent this risk is modifiable is unknown. Methods NHSII (Nurses' Health Study II) participants (N=4355), who r…
View article: Early prediction of gestational diabetes mellitus based on systematically selected multi-panel biomarkers and clinical accessibility—a longitudinal study of a multi-racial pregnant cohort
Early prediction of gestational diabetes mellitus based on systematically selected multi-panel biomarkers and clinical accessibility—a longitudinal study of a multi-racial pregnant cohort Open
This study suggested that a selected panel of cardiometabolic biomarkers using early-pregnancy random plasma samples predicted GDM comparably to those using mid-pregnancy fasting samples.
View article: Pre-pregnancy inflammatory and insulinemic dietary patterns and risk of gestational diabetes mellitus: a prospective cohort study of 14,674 women
Pre-pregnancy inflammatory and insulinemic dietary patterns and risk of gestational diabetes mellitus: a prospective cohort study of 14,674 women Open
In a large US cohort of predominantly White women, higher intake of pro-inflammatory and hyperinsulinemic diets was associated with increased risk of GDM. Further studies are warranted to confirm our findings, to provide evidence promoting…
View article: Longitudinal plasma amino acids during pregnancy and neonatal anthropometry: findings from the NICHD Fetal Growth Studies-Singleton Cohort
Longitudinal plasma amino acids during pregnancy and neonatal anthropometry: findings from the NICHD Fetal Growth Studies-Singleton Cohort Open
Clinical Trial Registry number: NCT00912132.
View article: Exploring the link between age at menarche, anthropometry and body fat composition with type II diabetes in a Singapore multi-ethnic cohort
Exploring the link between age at menarche, anthropometry and body fat composition with type II diabetes in a Singapore multi-ethnic cohort Open
Our study provided valuable insight into the pathophysiology of T2D development amongst mid-life women with early AAM. The findings could potentially indicate strategies to target FMI and VAT among Asian women in the menopausal phase with …
View article: Effects of electronic excitation on cascade dynamics in tungsten
Effects of electronic excitation on cascade dynamics in tungsten Open
While tungsten has emerged as a primary candidate for plasma-facing components in future fusion devices, the effects of electronic excitations on the irradiation damage behavior under high-energy irradiation remain unclear. In this work, u…
View article: Differential contributions of lean and fat mass on bone mineral density in Asian women of reproductive age: the Singapore Preconception Study of Long-Term Maternal and Child Outcomes study
Differential contributions of lean and fat mass on bone mineral density in Asian women of reproductive age: the Singapore Preconception Study of Long-Term Maternal and Child Outcomes study Open
The relationships between fat mass (FM), lean mass (LM), and bone mass are complex with significant implications for obesity, sarcopenia, and osteoporosis later in life. While greater LM is associated with higher BMD, the association betwe…
View article: Sleep Characteristics and Long-Term Risk of Type 2 Diabetes Among Women With Gestational Diabetes
Sleep Characteristics and Long-Term Risk of Type 2 Diabetes Among Women With Gestational Diabetes Open
Importance Women with a history of gestational diabetes (GD) are at high risk for developing type 2 diabetes (T2D). Sleep is a crucial lifestyle factor associated with cardiometabolic health, yet studies on its role in the progression from…