Aruna D. Pradhan
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View article: Unsupervised Learning Analysis of Triglycerides, Inflammation, Cholesterol, and the Risks of Incident Cardiovascular Disease and Type 2 Diabetes in the Women's Health Study
Unsupervised Learning Analysis of Triglycerides, Inflammation, Cholesterol, and the Risks of Incident Cardiovascular Disease and Type 2 Diabetes in the Women's Health Study Open
Background Traditional cardiovascular risk assessment entails investigator‐defined exposure levels and individual risk markers in multivariable analysis. We sought to determine whether an alternative unbiased learning analysis might provid…
View article: Effectiveness of Transcarotid vs Transfemoral Carotid Stenting for Stroke Prevention
Effectiveness of Transcarotid vs Transfemoral Carotid Stenting for Stroke Prevention Open
Importance The effectiveness of surgical transcarotid artery revascularization (TCAR) compared with percutaneous transfemoral carotid artery stenting (TF-CAS) for stroke prevention beyond the periprocedural period is poorly quantified. Obj…
View article: Comprehensive Evaluation of Role of Metabolic Biomarkers in Atherosclerotic Plaque Microenvironment: The Enigma in Its Origin and Regression
Comprehensive Evaluation of Role of Metabolic Biomarkers in Atherosclerotic Plaque Microenvironment: The Enigma in Its Origin and Regression Open
Atherosclerosis, a lipid driver chronic inflammatory pathophysiological process, has been the centerpiece of cardiovascular disease (CVD), cerebrovascular accidents, and other arterial pathology-related morbidities. It has simultaneously b…
View article: 8564 Vitamin D Supplementation And Incident Type 2 Diabetes In The Vitamin D And Omega-3 Trial
8564 Vitamin D Supplementation And Incident Type 2 Diabetes In The Vitamin D And Omega-3 Trial Open
Disclosure: D.K. Tobias: None. A. Pradhan: None. E. Duran: None. C. Li: None. Y. Song: None. J. Buring: None. N. Cook: None. S. Mora: None. J.E. Manson: None. Background: Observational and experimental evidence suggest a role for vitamin D…
View article: 9276 Vitamin D Supplementation And Incident Type 2 Diabetes In The Vitamin D And Omega-3 Trial
9276 Vitamin D Supplementation And Incident Type 2 Diabetes In The Vitamin D And Omega-3 Trial Open
Disclosure: D.K. Tobias: None. A. Pradhan: None. E. Duran: None. C. Li: None. Y. Song: None. J. Buring: None. N. Cook: None. S. Mora: None. J.E. Manson: None. Background: Observational and experimental evidence suggest a role for vitamin D…
View article: Effect of Using Learning Stations Strategy in Teaching Biology
Effect of Using Learning Stations Strategy in Teaching Biology Open
This study explored on the use of learning stations strategy to differentiate instructions while teaching and learning among Biology students of XII Science at Peljorling Higher Secondary School.The study was designed to understand the eff…
View article: C-Reactive Protein and Risk of Cardiovascular Events and Mortality in Patients with Various Cardiovascular Disease Locations
C-Reactive Protein and Risk of Cardiovascular Events and Mortality in Patients with Various Cardiovascular Disease Locations Open
Anti-inflammatory drugs reduce the risk of cardiovascular events in patients with coronary artery disease (CAD), but less is known about the relation between inflammation and outcomes in patients with cerebrovascular disease (CeVD), periph…
View article: Late-Breaking Science Abstracts and Featured Science Abstracts From the American Heart Association's Scientific Sessions 2022 and Late-Breaking Abstracts in Resuscitation Science From the Resuscitation Science Symposium 2022
Late-Breaking Science Abstracts and Featured Science Abstracts From the American Heart Association's Scientific Sessions 2022 and Late-Breaking Abstracts in Resuscitation Science From the Resuscitation Science Symposium 2022 Open
HomeCirculationVol. 146, No. 25Late-Breaking Science Abstracts and Featured Science Abstracts From the American Heart Association's Scientific Sessions 2022 and Late-Breaking Abstracts in Resuscitation Science From the Resuscitation Scienc…
View article: Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk
Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk Open
Among patients with type 2 diabetes, mild-to-moderate hypertriglyceridemia, and low HDL and LDL cholesterol levels, the incidence of cardiovascular events was not lower among those who received pemafibrate than among those who received pla…
View article: Inflammation and risk of recurrent cardiovascular events according to prior vascular disease location
Inflammation and risk of recurrent cardiovascular events according to prior vascular disease location Open
Background In recent years, anti-inflammatory drugs have been shown to reduce the risk of recurrent cardiovascular disease (CVD) events in patients with coronary artery disease (CAD), but have not yet been tested in patients with other vas…
View article: Efficacy of Marine ω-3 Fatty Acid Supplementation vs Placebo in Reducing Incidence of Dry Eye Disease in Healthy US Adults
Efficacy of Marine ω-3 Fatty Acid Supplementation vs Placebo in Reducing Incidence of Dry Eye Disease in Healthy US Adults Open
ClinicalTrials.gov Identifier: NCT01880463.
View article: Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease
Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease Open
Background: Lipoprotein-related traits have been consistently identified as risk factors for atherosclerotic cardiovascular disease, largely on the basis of studies of coronary artery disease (CAD). The relative contributions of specific l…
View article: Homocysteine Is Associated With Future Venous Thromboembolism in 2 Prospective Cohorts of Women
Homocysteine Is Associated With Future Venous Thromboembolism in 2 Prospective Cohorts of Women Open
Objective: Case-control studies have identified plasma homocysteine as a risk marker for venous thromboembolism (VTE). Prospective data, particularly among women, are sparse. We examined whether plasma homocysteine associates with incident…
View article: Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease
Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease Open
Background Circulating lipid and lipoprotein levels have consistently been identified as risk factors for atherosclerotic cardiovascular disease (ASCVD), largely on the basis of studies focused on coronary artery disease (CAD). The relativ…
View article: Association of the Mediterranean Diet With Onset of Diabetes in the Women’s Health Study
Association of the Mediterranean Diet With Onset of Diabetes in the Women’s Health Study Open
In this cohort study, higher MED intake scores were associated with a 30% relative risk reduction in type 2 diabetes during a 20-year period, which could be explained in large part by biomarkers of insulin resistance, BMI, lipoprotein meta…
View article: Triglyceride-Rich Lipoprotein Remnants and Cardiovascular Disease
Triglyceride-Rich Lipoprotein Remnants and Cardiovascular Disease Open
Background Triglycerides, cholesterol, and their metabolism are linked due to shared packaging and transport within circulating lipoprotein particles. While a case for a causal role of cholesterol-carrying low-density lipoproteins (LDLs) i…
View article: Adverse Effects of Low-Dose Methotrexate
Adverse Effects of Low-Dose Methotrexate Open
National Institutes of Health.
View article: Plasma Placental Growth Factor Concentrations Are Elevated Well in Advance of Type 2 Diabetes Mellitus Onset: Prospective Data From the WHS
Plasma Placental Growth Factor Concentrations Are Elevated Well in Advance of Type 2 Diabetes Mellitus Onset: Prospective Data From the WHS Open
Background Pathologic angiogenesis is a hallmark of type 2 diabetes mellitus (T2DM) microvascular complications and may modulate adipogenesis and precede the onset of clinical diabetes mellitus; however, longitudinal data are unavailable. …