Catherine Arnaud
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View article: A new tool to study the effects of in utero medication exposure on neurodevelopment in children
A new tool to study the effects of in utero medication exposure on neurodevelopment in children Open
Here we describe the implementation of a new tool that would allow to assess the risk of serious disability following in utero exposure to medications. The overall objective was to enrich the EFEMERIS database [Évaluation chez la Femme Enc…
View article: Microplastic exposure and effect on loggerhead turtle health
Microplastic exposure and effect on loggerhead turtle health Open
Plastic forms the majority (i.e. 75%) of marine waste with 14.5 million tons per year of dumped into the oceans. Once at sea, sunlight, wind, and wave action break down macroplastic waste into small particles. These microplastics (MPs, par…
View article: Neurodevelopmental outcomes at age 5 years among children born very preterm and surviving after persistent pulmonary hypertension of the newborn: EPIPAGE-2 cohort study
Neurodevelopmental outcomes at age 5 years among children born very preterm and surviving after persistent pulmonary hypertension of the newborn: EPIPAGE-2 cohort study Open
In this nationwide population-based cohort of extremely preterm and very preterm infants, moderate to severe overall neurodevelopmental disability at age 5 was significantly associated with neonatal PH.
View article: Early oxytocin treatment in infants with Prader–Willi syndrome is safe and is associated with better endocrine, metabolic and behavioral outcomes
Early oxytocin treatment in infants with Prader–Willi syndrome is safe and is associated with better endocrine, metabolic and behavioral outcomes Open
Background Oxytocin (OT) plays an important role in modulating behavior, social interactions and feeding. Prader–Willi syndrome (PWS), a rare genetic neurodevelopmental disorder, is a model of hypothalamic disorder including OT dysfunction…
View article: Postneonatal Cerebral Palsy in Europe: Prevalence and Clinical Characteristics According to Contributory Events: An <scp>SCPE</scp> Study
Postneonatal Cerebral Palsy in Europe: Prevalence and Clinical Characteristics According to Contributory Events: An <span>SCPE</span> Study Open
Background Postneonatal cerebral palsy (PNCP) is rare and requires large databases to be studied over time. Objectives To study the time trend of prevalence of PNCP overall and by cause, and to describe the clinical characteristics of chil…
View article: “French Phage Network” annual conference—eighth meeting report
“French Phage Network” annual conference—eighth meeting report Open
The French Phage Network organizes a scientific meeting every year in which the community of researchers from academia and industry, as well as clinicians participate due to the growing interest in phage therapy. Although centered on givin…
View article: How does the environmental inadequacy mediate the effect of functional limitations on participation restrictions in young adults with cerebral palsy?
How does the environmental inadequacy mediate the effect of functional limitations on participation restrictions in young adults with cerebral palsy? Open
The environment considered as suggested by the ICF had only a minimal mediating effect in our study. However, public health policies must give priority to improvements at the macro-environmental level, particularly in terms of availability…
View article: Neurodevelopmental outcome in children between one and five years after persistent pulmonary hypertension of term and near-term newborns
Neurodevelopmental outcome in children between one and five years after persistent pulmonary hypertension of term and near-term newborns Open
Background Persistent pulmonary hypertension of the newborn (PPHN) is a serious condition that affects 1–2 per 1,000 newborns. Scientific data report the existence of neurological developmental abnormalities between 10 and 30%, but the des…
View article: Early oxytocin treatment in infants with Prader-Willi is safe and is associated with better endocrine metabolic and behavior outcomes.
Early oxytocin treatment in infants with Prader-Willi is safe and is associated with better endocrine metabolic and behavior outcomes. Open
Background: Oxytocin (OT) plays an important role in modulating behavior social interactions and feeding. Prader-Willi syndrome (PWS), a rare genetic neurodevelopmental disorder, is a model of hypothalamic disorder including OT dysfunction…
View article: Unmet environmental needs and unmet healthcare needs in a population of young adults with cerebral palsy: what the SPARCLE study tells us
Unmet environmental needs and unmet healthcare needs in a population of young adults with cerebral palsy: what the SPARCLE study tells us Open
Introduction Optimizing care for young adults with cerebral palsy is crucial for their physical and psychological well-being. The inadequacy of proximal environment may play a role in the provision of health services. The aim of this study…
View article: Satisfaction with health care services in young people with cerebral palsy in the transition period: results from a European multicenter study
Satisfaction with health care services in young people with cerebral palsy in the transition period: results from a European multicenter study Open
Background Young people with chronic health conditions and disabilities rely on the healthcare system to maintain their best possible health. The appropriate delivery and utilization of healthcare services are key to improve their autonomy…
View article: Assessing the Adequacy of the Physical, Social, and Attitudinal Environment to the Specific Needs of Young Adults With Cerebral Palsy: The European Adult Environment Questionnaire
Assessing the Adequacy of the Physical, Social, and Attitudinal Environment to the Specific Needs of Young Adults With Cerebral Palsy: The European Adult Environment Questionnaire Open
The EAEQ describes in detail the adequacy of the environment to the specific needs of young adults with CP. Its ICF-based structure opens up possibilities for use in a universal conceptual framework.
View article: Left atrial appendage geometry and function using transesophageal three-dimensional echocardiography in atrial fibrillation: a new approach to characterize left atrial thrombogenic milieu
Left atrial appendage geometry and function using transesophageal three-dimensional echocardiography in atrial fibrillation: a new approach to characterize left atrial thrombogenic milieu Open
Background Little data is available on the evaluation of left atrial appendage (LAA) geometry and function using three-Dimensional (3D) transoesophageal echocardiography (TEE). Purpose We hypothesized that 3D LAA geometry evaluated using d…
View article: Employment and higher education in young adults with cerebral palsy: a cross-sectional analysis of the SPARCLE study
Employment and higher education in young adults with cerebral palsy: a cross-sectional analysis of the SPARCLE study Open
Introduction For young people with disabilities, access to higher education and employment should lead to improved personal self-esteem and well-being and, in the long run, to increased inclusion in society. Our aims were to describe the e…
View article: Refining the prognosis of patients with AF using 3D transesophageal echocardiography of the left atrial appendage
Refining the prognosis of patients with AF using 3D transesophageal echocardiography of the left atrial appendage Open
Background Left atrial (LA) volume is considered an echocardiographic marker of thrombosis risk and prognosis in atrial fibrillation (AF). Limited data is available on the prognostic value of left atrial appendage (LAA) volume in AF as eva…
View article: Prevalence, Clinical Features, Neuroimaging, and Genetic Findings in Children With Ataxic Cerebral Palsy in Europe
Prevalence, Clinical Features, Neuroimaging, and Genetic Findings in Children With Ataxic Cerebral Palsy in Europe Open
This register-based multicenter study on children with ataxic CP provides a large sample size for the analysis of prevalence, severity, and origin of this rare CP subtype. Even with strict inclusion and classification criteria, there is va…
View article: Cognitive Training for Visuospatial Processing in Children Aged 5½ to 6 Years Born Very Preterm With Working Memory Dysfunction
Cognitive Training for Visuospatial Processing in Children Aged 5½ to 6 Years Born Very Preterm With Working Memory Dysfunction Open
Importance Compared with term-born peers, children born very preterm generally perform poorly in executive functions, particularly in working memory and inhibition. By taking advantage of neuroplasticity, computerized cognitive training of…
View article: Pulmonary hypertension among preterm infants born at 22 through 32 weeks gestation in France: Prevalence, survival, morbidity and management in the EPIPAGE-2 cohort study
Pulmonary hypertension among preterm infants born at 22 through 32 weeks gestation in France: Prevalence, survival, morbidity and management in the EPIPAGE-2 cohort study Open
In this population-based cohort of very preterm infants, the prevalence of PH was 6 %. PH was associated with a significant decrease of survival without severe morbidity in this population.
View article: Long‐term outcomes of paediatric Guillain–Barré syndrome
Long‐term outcomes of paediatric Guillain–Barré syndrome Open
Aim To study long‐term sequelae in children with Guillain–Barré syndrome (GBS). Method This was a prospective observational study with children from two French tertiary centres. Data were from clinical and several standardized scales or qu…
View article: Classification of events contributing to postneonatal cerebral palsy: Development, reliability, and recommendations for use
Classification of events contributing to postneonatal cerebral palsy: Development, reliability, and recommendations for use Open
Aim This paper introduces the Surveillance of Cerebral Palsy in Europe (SCPE) classification of events contributing to postneonatally acquired cerebral palsy, presents its interrater reliability, and describes the cases identified in the S…
View article: PROMPT: Prospective Meta-analysis for Pessary Trials Study Protocol
PROMPT: Prospective Meta-analysis for Pessary Trials Study Protocol Open
Objective Preterm birth, defined as birth before 37 weeks of gestation, is a leading cause of perinatal and infant mortality throughout the world. Preterm birth is also associated with long-term neurological disabilities and other signific…
View article: Efficacy and Safety of Eculizumab in Pediatric Patients Affected by Shiga Toxin–Related Hemolytic and Uremic Syndrome: A Randomized, Placebo-Controlled Trial
Efficacy and Safety of Eculizumab in Pediatric Patients Affected by Shiga Toxin–Related Hemolytic and Uremic Syndrome: A Randomized, Placebo-Controlled Trial Open
Significance Statement Shiga toxin–related hemolytic uremic syndrome (STEC-HUS) is a serious condition, characterized by multiorgan thrombotic microangiopathy, mainly affecting children. Renal involvement is severe, with approximately half…