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View article: P056 A case of refractory dermatomyositis responding to upadacitinib
P056 A case of refractory dermatomyositis responding to upadacitinib Open
Introduction Dermatomyositis is an inflammatory myopathy involving proximal muscle weakness and cutaneous manifestations, with additional organ involvement possible. Treatment relies on immunosuppression, typically with corticosteroids and…
View article: P038 Clinical and histopathological features of purpura fulminans: a retrospective case series
P038 Clinical and histopathological features of purpura fulminans: a retrospective case series Open
Purpura fulminans (PF) is a rare but serious condition characterized by purpura and skin necrosis resulting from a hypercoagulable state. This study aimed to evaluate the clinical, histopathological and laboratory features, alongside manag…
View article: BI12 Systematic review of checkpoint inhibitor-induced epidermal necrolysis: a clinical entity distinct from ‘classic’ Stevens–Johnson syndrome/toxic epidermal necrolysis
BI12 Systematic review of checkpoint inhibitor-induced epidermal necrolysis: a clinical entity distinct from ‘classic’ Stevens–Johnson syndrome/toxic epidermal necrolysis Open
The use of immune checkpoint inhibitors in the treatment of cancer has transformed the prognosis and outcomes for patients with cancer. However, immune checkpoint inhibitor epidermal necrolysis (ICI-EN), a cutaneous immune-related adverse …
View article: DP01 (P038) Clinical and histopathological features of purpura fulminans: a retrospective case series
DP01 (P038) Clinical and histopathological features of purpura fulminans: a retrospective case series Open
Purpura fulminans (PF) is a rare but serious condition characterized by purpura and skin necrosis resulting from a hypercoagulable state. This study aimed to evaluate the clinical, histopathological and laboratory features, alongside manag…
View article: Annular Elastolytic Giant Cell Granuloma Associated with Autoimmune Hepatitis: Response to Ciclosporin
Annular Elastolytic Giant Cell Granuloma Associated with Autoimmune Hepatitis: Response to Ciclosporin Open
A 47 year old Caucasian female with a background of type 2 diabetes mellitus, hypothyroidism, and autoimmune hepatitis presented with a painful, pruritic, papular eruption in a photosensitive distribution across the upper chest, neck, face…
View article: Outcomes of jaundice in advanced hepatocellular carcinoma – a sub-Saharan perspective
Outcomes of jaundice in advanced hepatocellular carcinoma – a sub-Saharan perspective Open
Jaundice is a marker of advanced disease and poor outcomes in hepatocellular carcinoma (HCC). The aim of this study was to describe and analyse the management and outcomes of jaundiced HCC patients at a large academic referral centre in su…
View article: Acute hepatic failure in trimethoprim-induced drug rash with eosinophilia and systemic symptoms (DRESS)
Acute hepatic failure in trimethoprim-induced drug rash with eosinophilia and systemic symptoms (DRESS) Open
In this paper, we describe four cases of drug rash with eosinophilia and systemic symptoms (DRESS) caused by trimethoprim administered for the treatment of acne. All cases were complicated by acute hepatic failure.
View article: P35 Dermatomyositis with retinal involvement: a case series
P35 Dermatomyositis with retinal involvement: a case series Open
Case report - Introduction Dermatomyositis (DM) is a multisystem, autoimmune condition. It belongs to a spectrum of idiopathic inflammatory myopathies (IIMs) which can present with proximal muscle weakness or cutaneous lesions, but can als…
View article: Case of Fatal Immune-Related Skin Toxicity From Sequential Use of Osimertinib After Pembrolizumab: Lessons for Drug Sequencing in Never-Smoking Non–Small-Cell Lung Cancer
Case of Fatal Immune-Related Skin Toxicity From Sequential Use of Osimertinib After Pembrolizumab: Lessons for Drug Sequencing in Never-Smoking Non–Small-Cell Lung Cancer Open
DiagnosisCT, PET/CT and MRI brain: Stage IVB (T2b N3 M1) NSCLC EBUS: TTF1-positive adenocarcinoma
View article: A very peculiar practice: dermatology in the era of COVID‐19
A very peculiar practice: dermatology in the era of COVID‐19 Open
Aren't you one of the dermatology consultants?'thestaff nurse was looking at me with slightly narrowed eyes, and an expression that wavered between curiosity, confusion and amusement . . .and then settled on fear and blind panic.It was Sat…
View article: BAD guidelines for SJS/TEN in children and young people, 2018
BAD guidelines for SJS/TEN in children and young people, 2018 Open
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are urgent, serious immune reactions in which there is skin loss and severe ulcers in the mouth, eyes and genital areas. It affects about 5‐6 people per million under 18 y…
View article: Contrast media and cutaneous reactions. Part 2: Delayed hypersensitivity reactions to iodinated contrast media
Contrast media and cutaneous reactions. Part 2: Delayed hypersensitivity reactions to iodinated contrast media Open
Contrast media (CM) are an indispensable part of modern medical imaging. Adverse reactions to CM are uncommon, but frequently involve cutaneous symptoms. This two-part article reviews adverse events secondary to CM that are relevant to the…
View article: British Association of Dermatologists' guidelines for the management of Stevens–Johnson syndrome/toxic epidermal necrolysis in children and young people, 2018
British Association of Dermatologists' guidelines for the management of Stevens–Johnson syndrome/toxic epidermal necrolysis in children and young people, 2018 Open
Linked Comment:Lee. Br J Dermatol 2019; 181:10–11. Plain language summary available online
View article: Malnutrition and skin disease in Far East prisoners-of-war in World War II
Malnutrition and skin disease in Far East prisoners-of-war in World War II Open
During the Second World War, thousands of captured British and Commonwealth troops were interned in prisoner-of-war (POW) camps in the Far East. Imprisonment was extremely harsh, and prisoners developed multiple pathologies induced by phys…
View article: An unusual cause for a psoriasiform dermatosis
An unusual cause for a psoriasiform dermatosis Open
A 79-year-old woman presented with a 5-month history of a painful dermatosis affecting her hands and feet. This developed into inflammation with fissuring, affecting the fingers and toes. The patient was a current smoker with a 65-pack-yea…
View article: UK guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults 2016 (print summary – Full guidelines available at http://dx.doi.org/10.1016/j.bjps.2016.01.034)
UK guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults 2016 (print summary – Full guidelines available at http://dx.doi.org/10.1016/j.bjps.2016.01.034) Open
Summary The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for the diagnosis and management of the full spectrum of Stevens–Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and SJS-TEN o…
View article: Systemic hypersensitivity reaction to Omnipaque radiocontrast medium: a case of mini‐<scp>DRESS</scp>
Systemic hypersensitivity reaction to Omnipaque radiocontrast medium: a case of mini‐<span>DRESS</span> Open
Key Clinical Message Drug reaction with eosinophilia and systemic symptoms ( DRESS ) is a delayed drug reaction defined by physical signs and laboratory parameters. Mini‐ DRESS is a new entity, in cases that display some but not all featur…