Nimesh D. Desai
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View article: Incidence, predictors, and outcomes of major transcatheter aortic valve replacement (TAVR) complications and failure-to-rescue in the contemporary era
Incidence, predictors, and outcomes of major transcatheter aortic valve replacement (TAVR) complications and failure-to-rescue in the contemporary era Open
Objectives As transcatheter aortic valve replacement (TAVR) expands to lower-risk populations, understanding contemporary patterns of complications requiring surgical intervention remains critical. This study examines the incidence, predic…
View article: Multidisciplinary Management of Heritable Aortopathy in Pregnancy Complicated by Postpartum Acute Type A Dissection
Multidisciplinary Management of Heritable Aortopathy in Pregnancy Complicated by Postpartum Acute Type A Dissection Open
Patients with HTAD are at an increased risk of pregnancy-related aortic dissection. Key management principles include multidisciplinary evaluation, imaging surveillance, blood pressure control, and delivery with cardiothoracic surgical bac…
View article: Association Between Preoperative Palmar Arch Velocity on Duplex Ultrasonography and Ischemic Hand Symptoms After Radial Artery Harvest
Association Between Preoperative Palmar Arch Velocity on Duplex Ultrasonography and Ischemic Hand Symptoms After Radial Artery Harvest Open
Low palmar arch reversal velocity on preoperative duplex ultrasonography was not associated with an increased risk of hand ischemia after radial artery harvest. These findings suggest that harvesting the radial artery is safe in patients w…
View article: Surgical Volume and Outcomes of Intraoperative Transesophageal Echocardiography in Coronary Artery Bypass Grafting
Surgical Volume and Outcomes of Intraoperative Transesophageal Echocardiography in Coronary Artery Bypass Grafting Open
Importance The routine use of intraoperative transesophageal echocardiography (TEE) during coronary artery bypass graft (CABG) surgery remains controversial. Its benefit across different patient populations is unclear. Objectives To identi…
View article: Surgery Versus Surveillance: A Quality-of-Life Analysis of Patients With Moderately Dilated Aortic Root or Ascending Aorta
Surgery Versus Surveillance: A Quality-of-Life Analysis of Patients With Moderately Dilated Aortic Root or Ascending Aorta Open
Objectives The impact of diagnosis and management of ascending thoracic aortic aneurysm (ATAA) on patients’ quality of life (QoL) is not well characterized. This study aims to compare QoL with surgery versus surveillance in patients with m…
View article: Aortic Valve–Sparing Root Operation in Patients With Marfan and Loeys-Dietz Syndrome
Aortic Valve–Sparing Root Operation in Patients With Marfan and Loeys-Dietz Syndrome Open
VSRR shows excellent midterm outcomes in patients with MFS and LDS. There are no outcome differences between patients with MFS and patients with LDS. The use of a Valsalva graft may be considered to reduce aortic reintervention rates in pa…
View article: Management of the dissected aortic root in young patients: A propensity score-matched analysis of mechanical versus bioprosthetic aortic root replacement
Management of the dissected aortic root in young patients: A propensity score-matched analysis of mechanical versus bioprosthetic aortic root replacement Open
There is no survival advantage of mech-Bentall in ATAAD in young patients at 10 years, and it is associated with a significantly higher rate of morbid complications. When the aortic valve cannot be spared, bio-Bentall should be considered …
View article: Genome-First Approach to Rare and Common Variant Risk of Thoracic Aortic Aneurysm and Dissection
Genome-First Approach to Rare and Common Variant Risk of Thoracic Aortic Aneurysm and Dissection Open
Background Thoracic aortic aneurysm and dissection (TAAD) can have catastrophic health consequences. Eleven genes have strong or definitive evidence for causing heritable TAAD (HTAAD). However, patients are seldom tested for rare pathogeni…
View article: First reported surgical explantation of infected thoracic branched endograft requiring complex arch and descending thoracic aortic repair
First reported surgical explantation of infected thoracic branched endograft requiring complex arch and descending thoracic aortic repair Open
We present a 51-year-old woman with thoracic aortitis and rapidly enlarging descending thoracic aortic aneurysm in the setting of Clostridium septicum bacteraemia. After antibiotic treatment, she underwent left carotid–subclavian transposi…
View article: A Multicenter Clinical Trial on the Five-Year Outcomes Following Treatment of Acute, Complicated Type B Aortic Dissection With a Conformable Stent Graft
A Multicenter Clinical Trial on the Five-Year Outcomes Following Treatment of Acute, Complicated Type B Aortic Dissection With a Conformable Stent Graft Open
Treatment of patients with advanced pathophysiology with the CTAG device resulted in favorable long-term clinical and anatomic outcomes. Complete thrombosis of the false lumen and positive aortic remodeling was sustained throughout the stu…
View article: National Trends in the Use and Timing of Thoracic Endovascular Aneurysm Repair After Type B Aortic Dissection
National Trends in the Use and Timing of Thoracic Endovascular Aneurysm Repair After Type B Aortic Dissection Open
Nationally, interval TEVAR after medically managed TBAD has become much more common, although important disparities remain in its use.
View article: Polygenic Scoring for Detection of Ascending Thoracic Aortic Dilation
Polygenic Scoring for Detection of Ascending Thoracic Aortic Dilation Open
BACKGROUND: Ascending thoracic aortic dilation is a complex heritable trait that involves modifiable and nonmodifiable risk factors. Polygenic scores (PGS) are increasingly used to assess risk for complex diseases. The degree to which a PG…
View article: Outcomes of a Novel Single-Branched Aortic Stent Graft for Treatment of Type B Aortic Dissection
Outcomes of a Novel Single-Branched Aortic Stent Graft for Treatment of Type B Aortic Dissection Open
In this study of a novel branched endograft device to preserve the LSA in patients with type B dissection undergoing thoracic endovascular aortic repair, we demonstrate acceptable safety and efficacy outcomes at 1 year.
View article: Clinical cases referring to the 2023 EACTS/STS Guidelines for diagnosing and treating acute and chronic syndromes of the aortic organ
Clinical cases referring to the 2023 EACTS/STS Guidelines for diagnosing and treating acute and chronic syndromes of the aortic organ Open
Summary Clinical cases referring to the EACTS/STS Guidelines for diagnosing and treating acute and chronic syndromes of the aortic organ aim to assist physicians in selecting the best management strategies for individual patients with a gi…
View article: Deployment of a novel hybrid stent for open repair of acute DeBakey type I aortic dissection with malperfusion
Deployment of a novel hybrid stent for open repair of acute DeBakey type I aortic dissection with malperfusion Open
The AMDS Hybrid Prosthesis is a novel hybrid device for the treatment of acute DeBakey I aortic dissection in patients without an intimal tear in the arch. Central Picture Legend:The AMDS Hybrid Prosthesis is deployed antegrade during circ…
View article: Testing clinical selection criteria for intraoperative transoesophageal echocardiography in isolated coronary artery bypass graft surgery
Testing clinical selection criteria for intraoperative transoesophageal echocardiography in isolated coronary artery bypass graft surgery Open
Among US adults undergoing isolated CABG surgery, intraoperative TOE was associated with improved outcomes in patients with congestive heart failure (vs without) and among patients undergoing multivessel (vs single vessel) CABG. These find…