D E. Nicholson
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View article: Multilateral benefit-sharing from digital sequence information will support both science and biodiversity conservation
Multilateral benefit-sharing from digital sequence information will support both science and biodiversity conservation Open
Open access to sequence data is a cornerstone of biology and biodiversity research, but has created tension under the United Nations Convention on Biological Diversity (CBD). Policy decisions could compromise research and development, unle…
View article: Adaptation to genome decay in the structure of the smallest eukaryotic ribosome
Adaptation to genome decay in the structure of the smallest eukaryotic ribosome Open
The evolution of microbial parasites involves the counterplay between natural selection forcing parasites to improve and genetic drifts forcing parasites to lose genes and accumulate deleterious mutations. Here, to understand how this coun…
View article: Sal-type ABC-F proteins: intrinsic and common mediators of pleuromutilin resistance by target protection in staphylococci
Sal-type ABC-F proteins: intrinsic and common mediators of pleuromutilin resistance by target protection in staphylococci Open
The first member of the pleuromutilin (PLM) class suitable for systemic antibacterial chemotherapy in humans recently entered clinical use, underscoring the need to better understand mechanisms of PLM resistance in disease-causing bacteria…
View article: 'Lose-to-gain' adaptation to genome decay in the structure of the smallest eukaryotic ribosomes
'Lose-to-gain' adaptation to genome decay in the structure of the smallest eukaryotic ribosomes Open
The evolution of microbial parasites involves the interplay of two opposing forces. On the one hand, the pressure to survive drives parasites to improve through Darwinian natural selection. On the other, frequent genetic drifts result in g…