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View article: Engineering Mo <sub>2</sub> TiC <sub>2</sub> T <sub> <i>x</i> </sub> MXene Electrocatalyst via Metal‐Ion Intercalation Toward Efficient Hydrogen Evolution Reaction
Engineering Mo <sub>2</sub> TiC <sub>2</sub> T <sub> <i>x</i> </sub> MXene Electrocatalyst via Metal‐Ion Intercalation Toward Efficient Hydrogen Evolution Reaction Open
Developing highly efficient, stable, and low‐cost nonprecious metal electrocatalysts for the hydrogen evolution reaction (HER) is critical for scalable green hydrogen production. Herein, we designed a powerful metal ion intercalation strat…
View article: Roles of Macrophage Migration Inhibitory Factor (MIF) Signaling Pathway in Oncovirus Infection and Virus-Associated Cancers
Roles of Macrophage Migration Inhibitory Factor (MIF) Signaling Pathway in Oncovirus Infection and Virus-Associated Cancers Open
Approximately 12% of all human cancers are caused by oncoviruses. Macrophage migration inhibitory factor (MIF) signaling activation has been found closely related to many cancer cell malignant behaviors and infectious disease progression. …
View article: Recent Advances in Development of Kaposi's Sarcoma‐Associated Herpesvirus‐Latency‐Associated Nuclear Antigen Targeted Therapies
Recent Advances in Development of Kaposi's Sarcoma‐Associated Herpesvirus‐Latency‐Associated Nuclear Antigen Targeted Therapies Open
Kaposi's Sarcoma‐associated Herpesvirus (KSHV, also named as Human Herpesvirus 8, HHV‐8) represents a principal causative agent of several cancers arising in patients with compromised immune systems. The latency‐associated nuclear antigen …
View article: Lysine acetyltransferase 2A-mediated succinylation of adenosine monophosphate-activated protein kinase suppresses gallstone formation by inhibiting inflammation and pyroptosis
Lysine acetyltransferase 2A-mediated succinylation of adenosine monophosphate-activated protein kinase suppresses gallstone formation by inhibiting inflammation and pyroptosis Open
BACKGROUND Cholelithiasis is a prevalent biliary tract disorder primarily characterized by gallbladder or biliary stone formation. Although succinylation has been extensively studied as a protein post-translational modification, its role i…
View article: Contrastive and Variational Approaches in Self-Supervised Learning for Complex Data Mining
Contrastive and Variational Approaches in Self-Supervised Learning for Complex Data Mining Open
Complex data mining has wide application value in many fields, especially in the feature extraction and classification tasks of unlabeled data. This paper proposes an algorithm based on self-supervised learning and verifies its effectivene…
View article: Infection of human induced pluripotent stem cells by an oncogenic herpesvirus
Infection of human induced pluripotent stem cells by an oncogenic herpesvirus Open
Objective As one of the major human oncogenic viruses, Kaposi’s Sarcoma-associated Herpesvirus (KSHV) is closely related to several cancers such as Kaposi’s sarcoma (KS) and primary effusion lymphoma (PEL). KSHV can infect a broad tropism …
View article: Identification of RP‐54745, an IL‐1 Inhibitor Displaying Anticancer Activities for KSHV‐Related Primary Effusion Lymphoma
Identification of RP‐54745, an IL‐1 Inhibitor Displaying Anticancer Activities for KSHV‐Related Primary Effusion Lymphoma Open
Kaposi's sarcoma‐associated herpesvirus (KSHV) is the etiologic agent of several human cancers, including primary effusion lymphoma (PEL), usually seen in immunocompromised patients while lack of effective therapeutic options. Interleukin‐…
View article: Human endogenous retrovirus type K encoded Np9 oncoprotein induces DNA damage response
Human endogenous retrovirus type K encoded Np9 oncoprotein induces DNA damage response Open
Human endogenous retrovirus sequences (HERVs) constitute up to 8% of the human genome, yet not all HERVs remain silent passengers within our genomes. Some HERVs, especially the HERV type K (HERV‐K), have been found to be frequently transac…
View article: Development of human endogenous retrovirus type K‐ related treatments for human diseases
Development of human endogenous retrovirus type K‐ related treatments for human diseases Open
Human endogenous retroviruses (HERVs) constitute approximately 8% of the human genome and have long been regarded as silent passengers within our genomes. However, the reactivation of HERVs has been increasingly linked to a range of human …
View article: Role of lymphatic endothelium specific hyaluronan receptor 1 in virus infection and associated diseases
Role of lymphatic endothelium specific hyaluronan receptor 1 in virus infection and associated diseases Open
Lymphatic vessel endothelial hyaluronan receptor 1 (LYVE‐1) serves as a prominent marker for lymphatic endothelial cells (LECs) and is pivotal in the process of lymphangiogenesis, a critical factor in cancer development and metastasis. Ove…
View article: Tuning Morphology and Electronic Structure of Cobalt Metaphosphate Via Vanadium‐Doping for Efficient Water and Urea Splitting
Tuning Morphology and Electronic Structure of Cobalt Metaphosphate Via Vanadium‐Doping for Efficient Water and Urea Splitting Open
Designing efficient multifunctional electrocatalysts for water and urea splitting to produce green hydrogen presents a significant yet worthwhile challenge. Herein, the morphology and electronic structure of cobalt metaphosphate (Co 2 P 4 …
View article: Coinfections with additional oncoviruses in HPV+ individuals: Status, function and potential clinical implications
Coinfections with additional oncoviruses in HPV+ individuals: Status, function and potential clinical implications Open
Oncovirus infections account for an estimated 12%−20% of human cancers worldwide. High‐risk human papillomavirus (HPV) infection is the etiological agent of some malignancies such as cervical, oropharyngeal, anal, penile, vaginal, and vulv…
View article: Developing new ceramide analogs against non-small cell lung cancer (NSCLC)
Developing new ceramide analogs against non-small cell lung cancer (NSCLC) Open
Non-small cell lung cancer (NSCLC) constitutes the predominant form of lung cancer and stands as the leading cause of cancer-related mortality in the United States. Conventional chemotherapy and radiotherapy yield suboptimal responses in a…
View article: Systematic Review of the Application of Computational Fluid Dynamics for Adult Aortic Diseases
Systematic Review of the Application of Computational Fluid Dynamics for Adult Aortic Diseases Open
Contemporary evidence suggests that CFD can provide additional hemodynamic parameters, which have the potential to predict the progression of aortic lesions, the effect of surgical intervention, and prognosis.
View article: The risk and risk factors of chikungunya virus infection and rheumatological sequelae in a cohort of U.S. Military Health System beneficiaries: implications for the vaccine era
The risk and risk factors of chikungunya virus infection and rheumatological sequelae in a cohort of U.S. Military Health System beneficiaries: implications for the vaccine era Open
Background Understanding the risk of chikungunya virus (CHIKV) infection and rheumatic sequelae across populations, including travelers and the military, is critical. We leveraged the electronic medical records of about 9.5 million U.S. Mi…
View article: The association of left ventricular fraction shortening with cardiovascular events in peritoneal dialysis patients
The association of left ventricular fraction shortening with cardiovascular events in peritoneal dialysis patients Open
This study suggests that LVFS is independently associated with the increased risk of CVEs in PD patients, especially those with aged < 45 years, female, with hypertension and dyslipidemia.
View article: Electrochemical Activation‐Induced Structural Transformation in Ni(<scp>OH</scp>)<sub>2</sub>/<scp>Ti<sub>3</sub>C<sub>2</sub>T</scp><i><sub>x</sub></i>/<scp>NF</scp> Systems with Enhanced Electrochemical Performance for Hybrid Supercapacitors
Electrochemical Activation‐Induced Structural Transformation in Ni(<span>OH</span>)<sub>2</sub>/<span>Ti<sub>3</sub>C<sub>2</sub>T</span><i><sub>x</sub></i>/<span>NF</span> Systems with Enhanced Electrochemical Performance for Hybrid Supercapacitors Open
Exploring a novel strategy for large‐scale production of battery‐type Ni(OH) 2 ‐based composites, with excellent capacitive performance, is still greatly challenging. Herein, we developed a facile and cost‐effective strategy to in situ gro…
View article: Mechanism of Implicit Moral Decision in the Context of Non-deceptive Counterfeit Luxury Consumption
Mechanism of Implicit Moral Decision in the Context of Non-deceptive Counterfeit Luxury Consumption Open
The implicit moral decision exists widely in our daily life, such as the non-deceptive counterfeit luxury consumption, imitating artwork and so on, but its moral decision mechanism remains to be clarified. The implicit moral decision has t…