Riccardo Casadei
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View article: Does Adjuvant <i>Therapy</i> in Invasive Intraductal Papillary Mucinous Neoplasm of the Pancreas Improve Survival? A Systematic Review and Meta‐Analysis Using Trial Sequential Analysis
Does Adjuvant <i>Therapy</i> in Invasive Intraductal Papillary Mucinous Neoplasm of the Pancreas Improve Survival? A Systematic Review and Meta‐Analysis Using Trial Sequential Analysis Open
Objective This meta‐analysis aims to evaluate the efficacy of adjuvant therapy (ADJ) in patients with resected invasive IPMNs, compared with follow‐up (FUP). Methods A random effects meta‐analysis was performed. Meta‐regression analysis wa…
View article: The “Big short” of minimally invasive pancreaticoduodenectomy for pancreatic ductal adenocarcinoma. A cost-effectiveness analysis based on randomized trials
The “Big short” of minimally invasive pancreaticoduodenectomy for pancreatic ductal adenocarcinoma. A cost-effectiveness analysis based on randomized trials Open
The RDP and LPD were not cost-effective. OPD remained the best approach.
View article: Minimally Invasive vs Open Left Pancreatectomy for Resectable Pancreatic Cancer
Minimally Invasive vs Open Left Pancreatectomy for Resectable Pancreatic Cancer Open
Importance The DIPLOMA trial showed comparable radical resection rates after minimally invasive left pancreatectomy (MILP) and open left pancreatectomy (OLP) in patients with upfront resectable pancreatic cancer. Data on long-term overall …
View article: Patients’ Attitude toward Less Frequent Surveillance of Low-Risk Pancreatic Cysts: A Multicenter European Cohort Study
Patients’ Attitude toward Less Frequent Surveillance of Low-Risk Pancreatic Cysts: A Multicenter European Cohort Study Open
Background Recent studies show that low-risk pancreatic cysts may require less frequent monitoring. Future guidelines will likely adapt their recommendations accordingly. Our goal was to explore the willingness of individuals with a low-ri…
View article: Financial toxicity in patients followed for branch-duct intraductal papillary mucinous neoplasms: the risk that arises from “too much” for nothing
Financial toxicity in patients followed for branch-duct intraductal papillary mucinous neoplasms: the risk that arises from “too much” for nothing Open
FT can be seen in the BD-IPMN population. The patient's perspective must be taken into account during follow-up.
View article: Stage IV pancreatic ductal adenocarcinoma (PDAC) with synchronous liver metastasis: are there survival benefits in liver resection? A systematic review and meta-analysis
Stage IV pancreatic ductal adenocarcinoma (PDAC) with synchronous liver metastasis: are there survival benefits in liver resection? A systematic review and meta-analysis Open
In highly selected patients with metastatic PDAC who respond to systemic CT and receive post-operative systemic CT, ST could be associated with improved OS. However, the high heterogeneity and retrospective design of included studies limit…
View article: Exploring the Common Mutational Landscape in Cutaneous Melanoma and Pancreatic Cancer
Exploring the Common Mutational Landscape in Cutaneous Melanoma and Pancreatic Cancer Open
Cutaneous melanoma (CM) and pancreatic cancer are aggressive tumors whose incidences are rapidly increasing in the last years. This review aims to provide a complete and update description about mutational landscape in CM and pancreatic ca…
View article: Prophylactic Drain Placement and Postoperative Invasive Procedures After Gastrectomy
Prophylactic Drain Placement and Postoperative Invasive Procedures After Gastrectomy Open
Importance Evidence suggests that prophylactic abdominal drainage after gastrectomy for cancer may reduce postoperative morbidity and hospital stay but this evidence comes from small studies with a high risk of bias. Further research is ne…
View article: Clinicopathological predictive factors in long‐term survivors who underwent surgery for pancreatic ductal adenocarcinoma: A single‐center propensity score matched analysis
Clinicopathological predictive factors in long‐term survivors who underwent surgery for pancreatic ductal adenocarcinoma: A single‐center propensity score matched analysis Open
Background Long‐term survivors (LTSs) after pancreatic resection of pancreatic ductal adenocarcinoma (PDAC) represent a particular subgroup of patients that remains poorly understood. The primary endpoint was to identify clinicopathologica…
View article: Neoadjuvant 177Lu-DOTATATE for non-functioning pancreatic neuroendocrine tumours (NEOLUPANET): multicentre phase II study
Neoadjuvant 177Lu-DOTATATE for non-functioning pancreatic neuroendocrine tumours (NEOLUPANET): multicentre phase II study Open
Background Resection of non-functioning pancreatic neuroendocrine tumours (NF-PanNETs) is curative in most patients. The potential benefits of neoadjuvant treatments have, however, never been explored. The primary aim of this study was to …
View article: The value of splenectomy during left-sided pancreatectomy for pancreatic ductal adenocarcinoma: predefined subanalysis in the DIPLOMA randomized trial
The value of splenectomy during left-sided pancreatectomy for pancreatic ductal adenocarcinoma: predefined subanalysis in the DIPLOMA randomized trial Open
no abstract available
View article: Futility of Up-Front Resection for Anatomically Resectable Pancreatic Cancer
Futility of Up-Front Resection for Anatomically Resectable Pancreatic Cancer Open
Importance There are currently no clinically relevant criteria to predict a futile up-front pancreatectomy in patients with anatomically resectable pancreatic ductal adenocarcinoma. Objectives To develop a futility risk model using a multi…
View article: Standardizing definitions and terminology of left-sided pancreatic resections through an international Delphi consensus
Standardizing definitions and terminology of left-sided pancreatic resections through an international Delphi consensus Open
no abstract available
View article: 93P Evaluation of the prognostic tools in patients with localized liposarcomas, myxofibrosarcoma, undifferentiated pleomorphic sarcoma
93P Evaluation of the prognostic tools in patients with localized liposarcomas, myxofibrosarcoma, undifferentiated pleomorphic sarcoma Open
The study aims to evaluate the predictive factors of disease relapse in patients with soft tissue sarcoma, focusing on systemic and intratumoral immune status and molecular features, to guide optimal therapeutic planning and prevent diseas…
View article: REDISCOVER International Guidelines on the Perioperative Care of Surgical Patients With Borderline-resectable and Locally Advanced Pancreatic Cancer
REDISCOVER International Guidelines on the Perioperative Care of Surgical Patients With Borderline-resectable and Locally Advanced Pancreatic Cancer Open
Objective: The REDISCOVER consensus conference aimed at developing and validating guidelines on the perioperative care of patients with borderline-resectable (BR-) and locally advanced (LA) pancreatic ductal adenocarcinoma (PDAC). Backgrou…
View article: Real-Life Use of [68Ga]Ga-DOTANOC PET/CT in Confirmed and Suspected NETs from a Prospective 5-Year Electronic Archive at an ENETS Center of Excellence: More Than 2000 Scans in More Than 1500 Patients
Real-Life Use of [68Ga]Ga-DOTANOC PET/CT in Confirmed and Suspected NETs from a Prospective 5-Year Electronic Archive at an ENETS Center of Excellence: More Than 2000 Scans in More Than 1500 Patients Open
The recent introduction of novel treatments for advanced neuroendocrine tumors (NETs) and the well-established impact of clinical case discussion within dedicated multidisciplinary teams indicates the need to promote the centralization of …
View article: The Presence of an Aberrant Right Hepatic Artery Did Not Influence Surgical and Oncological Outcomes After Pancreaticoduodenectomy: A Comprehensive Systematic Review and Meta‐Analysis
The Presence of an Aberrant Right Hepatic Artery Did Not Influence Surgical and Oncological Outcomes After Pancreaticoduodenectomy: A Comprehensive Systematic Review and Meta‐Analysis Open
Background The presence of an aberrant right hepatic artery (a‐RHA) could influence the oncological and postoperative results after pancreaticoduodenectomy (PD). Methods A systematic review and metanalysis were conducted, including all com…