Dilip D. Giri
YOU?
Author Swipe
View article: Large adipocytes alter mode of lipid release and promote breast cancer malignancy
Large adipocytes alter mode of lipid release and promote breast cancer malignancy Open
Primary adipocytes possess a dramatic capacity to expand and retract in volume, leading to high variability in cell size within and between individuals. Yet, how adipocyte size impacts cell function remains unclear as adipocyte size is not…
View article: Breast Cancer Macrophage Heterogeneity and Self-renewal are Determined by Spatial Localization
Breast Cancer Macrophage Heterogeneity and Self-renewal are Determined by Spatial Localization Open
Summary Tumor-infiltrating macrophages support critical steps in tumor progression, and their accumulation in the tumor microenvironment (TME) is associated with adverse outcomes and therapeutic resistance across human cancers. In the TME,…
View article: Supplementary Figure 2 from Increased Levels of COX-2 and Prostaglandin E<sub>2</sub> Contribute to Elevated Aromatase Expression in Inflamed Breast Tissue of Obese Women
Supplementary Figure 2 from Increased Levels of COX-2 and Prostaglandin E<sub>2</sub> Contribute to Elevated Aromatase Expression in Inflamed Breast Tissue of Obese Women Open
PDF file - 98K
View article: Supplementary Table 2 from Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice
Supplementary Table 2 from Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice Open
Human Energy Responsive Methylation Changes in Normal Breast Tissue.
View article: Supplementary Data from Dietary Polyphenols Suppress Elevated Levels of Proinflammatory Mediators and Aromatase in the Mammary Gland of Obese Mice
Supplementary Data from Dietary Polyphenols Suppress Elevated Levels of Proinflammatory Mediators and Aromatase in the Mammary Gland of Obese Mice Open
Supplementary Data from Dietary Polyphenols Suppress Elevated Levels of Proinflammatory Mediators and Aromatase in the Mammary Gland of Obese Mice
View article: Figure S1 from Effects of Adiposity and Exercise on Breast Tissue and Systemic Metabo-Inflammatory Factors in Women at High Risk or Diagnosed with Breast Cancer
Figure S1 from Effects of Adiposity and Exercise on Breast Tissue and Systemic Metabo-Inflammatory Factors in Women at High Risk or Diagnosed with Breast Cancer Open
Figure S1. Breast SIRT1 levels correlate with adiposity. SIRT1 expression in the breast inversely correlated with (A) BMI, (B) adipocyte diameter, (C) total fat percentage, and (D) trunk fat percentage.
View article: Supplementary Table 3 from Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice
Supplementary Table 3 from Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice Open
Mouse Mapping Statistics, n=3/group.
View article: Data from Dietary Polyphenols Suppress Elevated Levels of Proinflammatory Mediators and Aromatase in the Mammary Gland of Obese Mice
Data from Dietary Polyphenols Suppress Elevated Levels of Proinflammatory Mediators and Aromatase in the Mammary Gland of Obese Mice Open
In postmenopausal women, obesity is a risk factor for the development of hormone receptor–positive breast cancer driven by estrogen. After menopause, aromatization of androgen precursors in adipose tissue is a major synthetic source of est…
View article: Data from Increased Levels of COX-2 and Prostaglandin E<sub>2</sub> Contribute to Elevated Aromatase Expression in Inflamed Breast Tissue of Obese Women
Data from Increased Levels of COX-2 and Prostaglandin E<sub>2</sub> Contribute to Elevated Aromatase Expression in Inflamed Breast Tissue of Obese Women Open
Obesity is a risk factor for hormone receptor-positive breast cancer in postmenopausal women. Estrogen synthesis is catalyzed by aromatase, which is encoded by CYP19. We previously showed that aromatase expression and activity are increase…
View article: Supplementary Data from Dietary Polyphenols Suppress Elevated Levels of Proinflammatory Mediators and Aromatase in the Mammary Gland of Obese Mice
Supplementary Data from Dietary Polyphenols Suppress Elevated Levels of Proinflammatory Mediators and Aromatase in the Mammary Gland of Obese Mice Open
Supplementary Data from Dietary Polyphenols Suppress Elevated Levels of Proinflammatory Mediators and Aromatase in the Mammary Gland of Obese Mice
View article: Supplementary Figure 1 Legend from Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice
Supplementary Figure 1 Legend from Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice Open
Supplementary Figure 1 Legend.
View article: Supplementary Table 1 from Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice
Supplementary Table 1 from Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice Open
IPA Biofunction Analysis. Significant disease or biofunction annotation implicated by IPA software.
View article: Supplementary Table 1 from A Randomized Multicenter Phase II Study of Docosahexaenoic Acid in Patients with a History of Breast Cancer, Premalignant Lesions, or Benign Breast Disease
Supplementary Table 1 from A Randomized Multicenter Phase II Study of Docosahexaenoic Acid in Patients with a History of Breast Cancer, Premalignant Lesions, or Benign Breast Disease Open
Clinicopathologic features stratified by treatment arm (RNA-seq analysis population).
View article: Supplementary Figure 1 from Increased Levels of COX-2 and Prostaglandin E<sub>2</sub> Contribute to Elevated Aromatase Expression in Inflamed Breast Tissue of Obese Women
Supplementary Figure 1 from Increased Levels of COX-2 and Prostaglandin E<sub>2</sub> Contribute to Elevated Aromatase Expression in Inflamed Breast Tissue of Obese Women Open
PDF file - 41K
View article: Data from Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice
Data from Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice Open
Using a murine model of basal-like breast cancer, we tested the hypothesis that chronic obesity, an established breast cancer risk and progression factor in women, induces mammary gland epigenetic reprogramming and increases mammary tumor …
View article: Data from Dietary Polyphenols Suppress Elevated Levels of Proinflammatory Mediators and Aromatase in the Mammary Gland of Obese Mice
Data from Dietary Polyphenols Suppress Elevated Levels of Proinflammatory Mediators and Aromatase in the Mammary Gland of Obese Mice Open
In postmenopausal women, obesity is a risk factor for the development of hormone receptor–positive breast cancer driven by estrogen. After menopause, aromatization of androgen precursors in adipose tissue is a major synthetic source of est…
View article: Supplementary Data from Obesity-associated Breast Inflammation among Hispanic/Latina Breast Cancer Patients
Supplementary Data from Obesity-associated Breast Inflammation among Hispanic/Latina Breast Cancer Patients Open
Sup Fig 1
View article: Supplementary Table 2 from Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice
Supplementary Table 2 from Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice Open
Human Energy Responsive Methylation Changes in Normal Breast Tissue.
View article: Supplementary Data from Obesity-associated Breast Inflammation among Hispanic/Latina Breast Cancer Patients
Supplementary Data from Obesity-associated Breast Inflammation among Hispanic/Latina Breast Cancer Patients Open
Sup Fig 1
View article: Supplementary Methods, Figures 1-9, Tables 1-3 from Genomic Complexity and AKT Dependence in Serous Ovarian Cancer
Supplementary Methods, Figures 1-9, Tables 1-3 from Genomic Complexity and AKT Dependence in Serous Ovarian Cancer Open
PDF file - 356K
View article: Data from Obesity-associated Breast Inflammation among Hispanic/Latina Breast Cancer Patients
Data from Obesity-associated Breast Inflammation among Hispanic/Latina Breast Cancer Patients Open
Breast white adipose tissue inflammation (BWATi) is associated with obesity and higher breast cancer risk among non-Hispanic white women. Obesity is prevalent in Hispanic/Latina patients with breast cancer, and the occurrence of BWATi in t…
View article: Data from Obesity-associated Breast Inflammation among Hispanic/Latina Breast Cancer Patients
Data from Obesity-associated Breast Inflammation among Hispanic/Latina Breast Cancer Patients Open
Breast white adipose tissue inflammation (BWATi) is associated with obesity and higher breast cancer risk among non-Hispanic white women. Obesity is prevalent in Hispanic/Latina patients with breast cancer, and the occurrence of BWATi in t…
View article: Data from Effects of Adiposity and Exercise on Breast Tissue and Systemic Metabo-Inflammatory Factors in Women at High Risk or Diagnosed with Breast Cancer
Data from Effects of Adiposity and Exercise on Breast Tissue and Systemic Metabo-Inflammatory Factors in Women at High Risk or Diagnosed with Breast Cancer Open
Excess body fat and sedentary behavior are associated with increased breast cancer risk and mortality, including in normal weight women. To investigate underlying mechanisms, we examined whether adiposity and exercise impact the breast mic…
View article: Supplementary Tables from Effects of Adiposity and Exercise on Breast Tissue and Systemic Metabo-Inflammatory Factors in Women at High Risk or Diagnosed with Breast Cancer
Supplementary Tables from Effects of Adiposity and Exercise on Breast Tissue and Systemic Metabo-Inflammatory Factors in Women at High Risk or Diagnosed with Breast Cancer Open
Supplementary Tables S1, S2, and S3
View article: Figure S1 from Effects of Adiposity and Exercise on Breast Tissue and Systemic Metabo-Inflammatory Factors in Women at High Risk or Diagnosed with Breast Cancer
Figure S1 from Effects of Adiposity and Exercise on Breast Tissue and Systemic Metabo-Inflammatory Factors in Women at High Risk or Diagnosed with Breast Cancer Open
Figure S1. Breast SIRT1 levels correlate with adiposity. SIRT1 expression in the breast inversely correlated with (A) BMI, (B) adipocyte diameter, (C) total fat percentage, and (D) trunk fat percentage.
View article: Data from Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice
Data from Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice Open
Using a murine model of basal-like breast cancer, we tested the hypothesis that chronic obesity, an established breast cancer risk and progression factor in women, induces mammary gland epigenetic reprogramming and increases mammary tumor …
View article: Data from A Randomized Multicenter Phase II Study of Docosahexaenoic Acid in Patients with a History of Breast Cancer, Premalignant Lesions, or Benign Breast Disease
Data from A Randomized Multicenter Phase II Study of Docosahexaenoic Acid in Patients with a History of Breast Cancer, Premalignant Lesions, or Benign Breast Disease Open
Obesity, a cause of subclinical inflammation, is a risk factor for the development of postmenopausal breast cancer and is associated with poorer cancer outcomes. Docosahexaenoic acid (DHA), an omega-3 fatty acid, possesses anti-inflammator…
View article: Supplementary Data from Dietary Polyphenols Suppress Elevated Levels of Proinflammatory Mediators and Aromatase in the Mammary Gland of Obese Mice
Supplementary Data from Dietary Polyphenols Suppress Elevated Levels of Proinflammatory Mediators and Aromatase in the Mammary Gland of Obese Mice Open
Supplementary Data from Dietary Polyphenols Suppress Elevated Levels of Proinflammatory Mediators and Aromatase in the Mammary Gland of Obese Mice
View article: Supplementary Methods, Figures 1-9, Tables 1-3 from Genomic Complexity and AKT Dependence in Serous Ovarian Cancer
Supplementary Methods, Figures 1-9, Tables 1-3 from Genomic Complexity and AKT Dependence in Serous Ovarian Cancer Open
PDF file - 356K