D. Győrik
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View article: Anxious temperament polygenic risk score predicts current depressive symptoms in a general population sample
Anxious temperament polygenic risk score predicts current depressive symptoms in a general population sample Open
View article: Revisiting affective temperaments in GWAS partially replicates previous results, and yields a novel significant variant for depressive temperament in ULK4
Revisiting affective temperaments in GWAS partially replicates previous results, and yields a novel significant variant for depressive temperament in ULK4 Open
View article: “… wise, amazed, temp’rate, and furious, Loyal and neutral, in a moment”: first heritability analysis of affective temperaments reports remarkably high SNP-based heritability
“… wise, amazed, temp’rate, and furious, Loyal and neutral, in a moment”: first heritability analysis of affective temperaments reports remarkably high SNP-based heritability Open
Introduction Depression shows a moderate heritability of 37-42%, which can be up to 75% in severely depressed samples 75%. At the same time SNP-based heritability of depression in GWAS-s is around 8-9%. Heterogeneity of the depressive phen…
View article: How does genetics contribute to endogenous and reactive depression? evidence from gene polymorphisms-based heritability and genetic correlations across multiple genome-wide association studies studies
How does genetics contribute to endogenous and reactive depression? evidence from gene polymorphisms-based heritability and genetic correlations across multiple genome-wide association studies studies Open
View article: Affective temperament polygenic risk scores predict lifetime and current depression in a general population sample
Affective temperament polygenic risk scores predict lifetime and current depression in a general population sample Open
View article: Affective temperament polygenic risk scores predict current depression in general population pilot study
Affective temperament polygenic risk scores predict current depression in general population pilot study Open
View article: “A melancholy…compounded of many simples, extracted from many objects”: heritability of affective temperaments suggests their role as endophenotypes for depression
“A melancholy…compounded of many simples, extracted from many objects”: heritability of affective temperaments suggests their role as endophenotypes for depression Open
View article: Genome-wide association studies suggests clock circadian regulator gene variation is involved in the emergence of depression following recent severe stress exposure
Genome-wide association studies suggests clock circadian regulator gene variation is involved in the emergence of depression following recent severe stress exposure Open
View article: Circadian rhythm and depression: CLOCK variation interacts with stress but not chronotype in impacting depression
Circadian rhythm and depression: CLOCK variation interacts with stress but not chronotype in impacting depression Open
View article: Inflamed Mind: Multiple Genetic Variants of IL6 Influence Suicide Risk Phenotypes in Interaction With Early and Recent Adversities in a Linkage Disequilibrium-Based Clumping Analysis
Inflamed Mind: Multiple Genetic Variants of IL6 Influence Suicide Risk Phenotypes in Interaction With Early and Recent Adversities in a Linkage Disequilibrium-Based Clumping Analysis Open
Background: Understanding and predicting suicide remains a challenge, and a recent paradigm shift regarding the complex relationship between the immune system and the brain brought attention to the involvement of inflammation in neuropsych…
View article: Every Night and Every Morn: Effect of Variation in CLOCK Gene on Depression Depends on Exposure to Early and Recent Stress
Every Night and Every Morn: Effect of Variation in CLOCK Gene on Depression Depends on Exposure to Early and Recent Stress Open
The role of circadian dysregulation is increasingly acknowledged in the background of depressive symptoms, and is also a promising treatment target. Similarly, stress shows a complex relationship with the circadian system. The CLOCK gene, …
View article: CLOCK, stress, depression
CLOCK, stress, depression Open
CLOCK, stress, depression