Dong‐Hoon Yang
YOU?
Author Swipe
View article: Efficacy and Safety of Bowel Cleansing with Mini S-Oral Sulfate Tablet versus the Conventional Oral Sulfate Tablet: A Prospective, Randomized, Investigator-Blinded, Multicenter, Noninferior, Phase 3 Trial
Efficacy and Safety of Bowel Cleansing with Mini S-Oral Sulfate Tablet versus the Conventional Oral Sulfate Tablet: A Prospective, Randomized, Investigator-Blinded, Multicenter, Noninferior, Phase 3 Trial Open
Compared with conventional OST, the mini S-OST split dose showed excellent efficacy, comparable safety and tolerability, with less gastric injury (ClinicalTrial.gov identifier NCT06287606).
View article: Atypical presentation of systemic lupus erythematosus flare with ileocecal ulceration and lymphadenopathy in a tuberculosis-endemic region
Atypical presentation of systemic lupus erythematosus flare with ileocecal ulceration and lymphadenopathy in a tuberculosis-endemic region Open
Rationale: Systemic lupus erythematosus can involve the gastrointestinal tract, but lupus enteritis (LE) with ileocecal ulceration and generalized lymphadenopathy as an initial presentation is exceptionally rare. In regions where tuberculo…
Evaluating the cross-reactivity of a stool methylated syndecan-2 (meSDC2) test in colorectal cancer detection Open
The stool meSDC2 test demonstrated a high positivity rate in CRC but showed low positivity rates in other cancers, except in biliary tract cancer. This indicates that the stool meSDC2 test has a high specificity for CRC, as the results are…
Joint association of frailty and depression with new-onset digestive disease among elderly Chinese population Open
Background Digestive diseases impose a substantial global health burden, yet the joint impact of frailty and depression on their incidence remains underexplored. Methods This cohort study analyzed 5,506 adults aged ≥ 65 years from the Chin…
Submucosal saline injection and mini-probe endoscopic ultrasound to assess endoscopic resectability of colorectal subepithelial tumors Open
Background/Aims: This study aimed to evaluate the feasibility and outcomes of mini-probe endoscopic ultrasound (mEUS) followed by submucosal saline injection (SSI-mEUS) for assessing the endoscopic resectability of colorectal subepithelial…
Clinical Utility of Endoscopic Ultrasound‐Guided Fine‐Needle Aspiration and Biopsy for Rectal and Perirectal Lesions With Categorization of Their Indications Open
Objectives Endoscopic ultrasound‐guided fine‐needle aspiration and/or biopsy (EUS‐FNA/B) is a diagnostic tool for gastrointestinal (GI) lesions. However, its effectiveness in the lower GI tract remains underreported. In this study, we aime…
Validation of the London Classification for Rectal Hyposensitivity in an Anorectal Manometry Database of 2540 Patients With Functional Defecatory Disorder Open
Defining RH based on 1 or more abnormal sensory thresholds showed better clinical correlation with patient characteristics. However, further prospective studies are needed to validate these findings before proposing revisions to the curren…
Differentiated digital transformation strategies in manufacturing: The impact of firm ownership on productivity Open
As information technology rapidly advances, digital transformation has become an important trend in enterprise development globally, particularly for manufacturing firms aiming to enhance productivity and competitiveness. This study examin…
View article: Artificial Intelligence Models May Aid in Predicting Lymph Node Metastasis in Patients with T1 Colorectal Cancer
Artificial Intelligence Models May Aid in Predicting Lymph Node Metastasis in Patients with T1 Colorectal Cancer Open
AI models trained on the basis of endoscopic findings and pathological features performed well in predicting LNM in patients with T1 CRC regardless of tumor location and initial treatment method.
View article: Survey of the Actual Practices Used for Endoscopic Removal of Colon Polyps in Korea: A Comparison with the Current Guidelines
Survey of the Actual Practices Used for Endoscopic Removal of Colon Polyps in Korea: A Comparison with the Current Guidelines Open
Adherence to the guidelines for endoscopic resection techniques varied depending on the characteristics of colorectal polyps. Thus, an individualized approach is required to increase adherence to the guidelines.
View article: P0729 Comparative clinical outcomes of advanced therapy in bio-naïve versus bio-experienced patients hospitalized with Acute Severe Ulcerative Colitis: A retrospective cohort study
P0729 Comparative clinical outcomes of advanced therapy in bio-naïve versus bio-experienced patients hospitalized with Acute Severe Ulcerative Colitis: A retrospective cohort study Open
Background The characteristics of patients with acute severe ulcerative colitis (ASUC) in East Asia differ from those in Western countries. However, the clinical outcomes of ASUC treated with advanced therapies (ATs; biologics or small mol…
View article: P0633 Real World Outcomes of Upadacitinib Induction Therapy for Patient with Inflammatory Bowel Disease in Korea
P0633 Real World Outcomes of Upadacitinib Induction Therapy for Patient with Inflammatory Bowel Disease in Korea Open
Background Upadacitnib (UPA) has demonstrated efficacy and safety in both patients with Crohn’s disease (CD) and ulcerative colitis (UC) in pivotal clinical trials.1,2 Still, there is a lack of data on real-world effectiveness and safety o…
Long‐Term Outcomes of Double‐Balloon Enteroscopy Polypectomy for Large Small Bowel Polyps Detected During Surveillance Imaging in Patients With Peutz–Jeghers Syndrome Open
Objectives Double‐balloon enteroscopy (DBE) is effective for managing small bowel (SB) diseases. We aimed to evaluate the patient outcomes of DBE polypectomy in Peutz–Jeghers syndrome (PJS) with large SB polyps at surveillance imaging stud…
View article: P1236 Temporal trends in obesity and its prognostic impact in Korean patients with inflammatory bowel disease
P1236 Temporal trends in obesity and its prognostic impact in Korean patients with inflammatory bowel disease Open
Background In recent decades, there has been an escalation in the prevalence of obese patients with Inflammatory Bowel Disease (IBD).1-3 In addition, the correlation between Body Mass Index (BMI) at the time of diagnosis and the prognostic…
Incidence, Risk Factors, and Outcomes of Chronic Antibiotic-Refractory Pouchitis in Korean Patients with Ulcerative Colitis Open
UC patients who were current smokers and previously used biologics/small molecules had a higher risk of developing CARP. Concomitant use of probiotics was less likely to be associated with CARP development.
Prevalence and risk factors of gallstone disease in Korean patients with ulcerative colitis Open
Background/Aims: The prevalence of gallstone disease in patients with ulcerative colitis (UC) is higher than in the general population. However, risk factors of gallstone disease in these patients remain unclear. Thus, we investigated the …
Clinical characteristics and long-term disease course in patients with Crohn’s disease as diagnosed by video capsule endoscopy: a multicenter retrospective matched case-control study Open
Background/Aims: Video capsule endoscopy is rarely used to diagnose Crohn’s disease in patients with negative ileocolonoscopy or cross-sectional image findings. We evaluated clinical characteristics and long-term outcomes of these rare cas…
Gut microbiome and metabolome signatures in liver cirrhosis-related complications Open
Background/Aims: Shifts in the gut microbiota and metabolites are interrelated with liver cirrhosis progression and complications. However, causal relationships have not been evaluated comprehensively. Here, we identified complication-depe…
View article: International consensus on the management of large (≥20 mm) colorectal laterally spreading tumors: World Endoscopy Organization Delphi study
International consensus on the management of large (≥20 mm) colorectal laterally spreading tumors: World Endoscopy Organization Delphi study Open
Objectives There have been significant advances in the management of large (≥20 mm) laterally spreading tumors (LSTs) or nonpedunculated colorectal polyps; however, there is a lack of clear consensus on the management of these lesions with…
Continuing or stopping 5‐aminosalicylates in patients with inflammatory bowel disease on anti‐<span>TNF</span> therapy: A nationwide population‐based study Open
Summary Background The impact of continuing or stopping 5‐aminosalicylates (5‐ASA) after commencing anti‐tumour necrosis factor (anti‐TNF) therapy in patients with inflammatory bowel disease (IBD) remains unclear. Aims To compare the outco…
Effectiveness of Switching to Subcutaneous Infliximab in Ulcerative Colitis Patients Experiencing Intravenous Infliximab Failure Open
In UC patients who experience IV infliximab failure during maintenance treatment, switching to SC infliximab may be a promising option because of better efficacy and safety.
Automatic assessment of bowel preparation by an artificial intelligence model and its clinical applicability Open
Background and Aim Reliable bowel preparation assessment is important in colonoscopy. However, current scoring systems are limited by laborious and time‐consuming tasks and interobserver variability. We aimed to develop an artificial intel…
SIRT1 exerts protective effects by inhibiting endoplasmic reticulum stress and NF-κB signaling pathways Open
Silent information regulator two homolog 1 (SIRT1), an NAD + -dependent histone deacetylase, plays a pivotal regulatory role in a myriad of physiological processes. A growing body of evidence suggests that SIRT1 can exert protective effect…
View article: A survey of current practices in post-polypectomy surveillance in Korea
A survey of current practices in post-polypectomy surveillance in Korea Open
Background/Aims: We investigated the clinical practice patterns of post-polypectomy colonoscopic surveillance among Korean endoscopists.Methods: In a web-based survey conducted between September and November 2021, participants were asked a…
Fecal Calprotectin in Patients with Crohn’s Disease: A Study Based on the History of Bowel Resection and Location of Disease Open
Fecal calprotectin (FC) is commonly used to assess Crohn’s disease (CD) activity. However, standardized cut-off values accounting for bowel resection history and disease location are lacking. In this study, we analyzed data from patients w…
Somatostatin receptor 2 (SSTR2) expression is associated with better clinical outcome and prognosis in rectal neuroendocrine tumors Open
Somatostatin analogues have recently been used as therapeutic targets for metastatic or surgically unresectable gastroenteropancreatic (GEP) neuroendocrine tumors (NETs), and associated somatostatin receptor (SSTR) expression has been well…
View article: Trends in colorectal cancer incidence according to an increase in the number of colonoscopy cases in Korea
Trends in colorectal cancer incidence according to an increase in the number of colonoscopy cases in Korea Open
BACKGROUND The incidence of colorectal cancer (CRC) and preinvasive CRC (e.g ., early colon cancer and advanced adenoma) is gradually increasing in several countries. AIM To evaluate the trend in incidence of CRC and preinvasive CRC accord…