Diana M. Hendrickx
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View article: Identification of potential inflammation markers for outgrowth of cow’s milk allergy
Identification of potential inflammation markers for outgrowth of cow’s milk allergy Open
Immunoglobulin E (IgE)-mediated cow’s milk allergy (CMA) is an immune-mediated reaction to cow’s milk (CM). Non-IgE-mediated CMA resolves in most children in the first years of life, whereas IgE-mediated CMA outgrowth is often later or not…
View article: A multi-omics machine learning classifier for outgrowth of cow's milk allergy in children
A multi-omics machine learning classifier for outgrowth of cow's milk allergy in children Open
A multi-omics machine learning classifier was developed to distinguish between infants that outgrew their cow's milk allergy and those who did not.
View article: Identification of potential inflammation markers for outgrowth of cow’s milk allergy
Identification of potential inflammation markers for outgrowth of cow’s milk allergy Open
Introduction Immunoglobulin E (IgE)-mediated cow’s milk allergy (CMA) is an immune-mediated reaction to cow’s milk (CM). Non-IgE-mediated CMA resolves in most children in the first years of life, whereas IgE-mediated CMA outgrowth is often…
View article: Current insights into cow's milk allergy in children: Microbiome, metabolome, and immune response—A systematic review
Current insights into cow's milk allergy in children: Microbiome, metabolome, and immune response—A systematic review Open
The increasing prevalence of IgE‐mediated cow's milk allergy (CMA) in childhood is a worldwide health concern. There is a growing awareness that the gut microbiome (GM) might play an important role in CMA development. Therefore, treatment …
View article: Trackability of proteins from probiotic Bifidobacterium spp. in the gut using metaproteomics
Trackability of proteins from probiotic Bifidobacterium spp. in the gut using metaproteomics Open
Beneficial effects of Bifidobacterium spp. on gut microbiota development and infant health have been reported earlier. Therefore, supplementation of infant formulas with probiotic bifidobacteria, as well as prebiotics stimulating bifidobac…
View article: Assessment of infant outgrowth of cow’s milk allergy in relation to the faecal microbiome and metaproteome
Assessment of infant outgrowth of cow’s milk allergy in relation to the faecal microbiome and metaproteome Open
Previous studies provide evidence for an association between modifications of the gut microbiota in early life and the development of food allergies. We studied the faecal microbiota composition (16S rRNA gene amplicon sequencing) and faec…
View article: A New Synuclein-Transgenic Mouse Model for Early Parkinson’s Reveals Molecular Features of Preclinical Disease
A New Synuclein-Transgenic Mouse Model for Early Parkinson’s Reveals Molecular Features of Preclinical Disease Open
Understanding Parkinson’s disease (PD), in particular in its earliest phases, is important for diagnosis and treatment. However, human brain samples are collected post-mortem, reflecting mainly end-stage disease. Because brain samples of m…
View article: A new synuclein-transgenic mouse model for early Parkinson’s reveals molecular features of preclinical disease
A new synuclein-transgenic mouse model for early Parkinson’s reveals molecular features of preclinical disease Open
Understanding Parkinson’s disease (PD) in particular in its earliest phases is important for diagnosis and treatment. However, human brain samples are collected post-mortem, reflecting mainly end stage disease. Because brain samples of mou…
View article: SimpactCyan 1.0: An Open-source Simulator for Individual-Based Models in HIV Epidemiology with R and Python Interfaces
SimpactCyan 1.0: An Open-source Simulator for Individual-Based Models in HIV Epidemiology with R and Python Interfaces Open
SimpactCyan is an open-source simulator for individual-based models in HIV epidemiology. Its core algorithm is written in C++ for computational efficiency, while the R and Python interfaces aim to make the tool accessible to the fast-growi…
View article: Influence of sexual risk behaviour and STI co-infection dynamics on the evolution of HIV set point viral load in MSM
Influence of sexual risk behaviour and STI co-infection dynamics on the evolution of HIV set point viral load in MSM Open
HIV viral load (VL) is an important predictor of HIV progression and transmission. Anti-retroviral therapy (ART) has been reported to reduce HIV transmission by lowering VL. However, apart from this beneficial effect, increased levels of p…
View article: Screening for hepatitis C at the emergency department: Should babyboomers also be screened in Belgium?
Screening for hepatitis C at the emergency department: Should babyboomers also be screened in Belgium? Open
Background & Aims Patients are not screened adequately for hepatitis C virus infection in Belgium. In the USA, the Center for Disease Control recommends screening for patients born in the babyboom period (1945‐1965). In Europe, the babyboo…
View article: SimpactCyan 1.0: An Open-source Simulator for Individual-Based Models in HIV Epidemiology with R and Python Interfaces
SimpactCyan 1.0: An Open-source Simulator for Individual-Based Models in HIV Epidemiology with R and Python Interfaces Open
SimpactCyan is an open-source simulator for individual-based models in HIV epidemiology. Its core algorithm is written in C++ for computational efficiency, while the R and Python interfaces aim to make the tool accessible to the fast-growi…
View article: The impact of behavioral interventions on co-infection dynamics: an exploration of the effects of home isolation
The impact of behavioral interventions on co-infection dynamics: an exploration of the effects of home isolation Open
Behavioral changes due to the development of symptoms have been studied in mono-infections. However, in reality, multiple infections are circulating within the same time period and behavioral changes resulting from contraction of one of th…