Douglas K. Rex
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View article: Risk of Post-Polypectomy Bleeding After Colorectal Endoscopic Mucosal Resection in Patients with Chronic Kidney Disease: A Propensity-Matched Analysis of the US Collaborative Network
Risk of Post-Polypectomy Bleeding After Colorectal Endoscopic Mucosal Resection in Patients with Chronic Kidney Disease: A Propensity-Matched Analysis of the US Collaborative Network Open
Background Studies evaluating the risk of post-polypectomy bleeding (PPB) after colorectal endoscopic mucosal resection (EMR) in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) are limited. Methods This retros…
View article: A30 THROUGH-THE-SCOPE CLIP WITH ANCHOR PRONGS FOR PROPHYLACTIC CLIP CLOSURE AFTER GI LESION RESECTION: A PROSPECTIVE COHORT STUDY
A30 THROUGH-THE-SCOPE CLIP WITH ANCHOR PRONGS FOR PROPHYLACTIC CLIP CLOSURE AFTER GI LESION RESECTION: A PROSPECTIVE COHORT STUDY Open
Background Endoscopic clipping following gastrointestinal (GI) lesion resection provides prophylaxis for delayed bleeding. A rotatable, anchor-pronged through-the-scope endoscopic clip (TTSC) underwent limited prospective study since comme…
View article: Performance of bowel preparation quality scales in patients with Crohn's disease
Performance of bowel preparation quality scales in patients with Crohn's disease Open
Summary Background The performance of bowel preparation (BP) in patients with Crohn's disease (CD) is unknown. Aims To evaluate the operating properties of instruments used to assess BP quality in patients with CD. Methods We used the Bost…
View article: International consensus on the management of large (≥20 mm) colorectal laterally spreading tumors: World Endoscopy Organization Delphi study
International consensus on the management of large (≥20 mm) colorectal laterally spreading tumors: World Endoscopy Organization Delphi study Open
Objectives There have been significant advances in the management of large (≥20 mm) laterally spreading tumors (LSTs) or nonpedunculated colorectal polyps; however, there is a lack of clear consensus on the management of these lesions with…
View article: A new through-the-scope clip with anchor prongs is safe and successful for a variety of endoscopic uses
A new through-the-scope clip with anchor prongs is safe and successful for a variety of endoscopic uses Open
Background and study aims Endoscopic through-the-scope clips (TTSC) are used for hemostasis and closure. We documented the performance of a new TTSC with anchor prongs. Patients and methods We conducted a prospective case series of the new…
View article: Using Computer-aided Optical Diagnosis and Expert Review to Evaluate Colorectal Polyps Diagnosed as Normal Mucosa in Pathology
Using Computer-aided Optical Diagnosis and Expert Review to Evaluate Colorectal Polyps Diagnosed as Normal Mucosa in Pathology Open
Pathological assessment of colorectal polyps is considered the current reference standard for histologic diagnosis. About 10% of polyps sent to the pathology lab are returned with the diagnosis of mucosal folds, mucosal prolapse, or normal…
View article: Computer-aided detection for colorectal neoplasia in randomized and non-randomized studies
Computer-aided detection for colorectal neoplasia in randomized and non-randomized studies Open
The widespread adoption of artificial intelligence (AI) for polyp detection in colonoscopy necessitates a thorough understanding of its benefits and harms. While AI has shown promise in increasing the adenoma detection rate (ADR), potentia…
View article: Audit of hemostatic clip use after colorectal polyp resection in an academic endoscopy unit
Audit of hemostatic clip use after colorectal polyp resection in an academic endoscopy unit Open
Background and study aims Prophylactic closure of endoscopic resection defects reduces delayed hemorrhage after resection of non-pedunculated colorectal lesions ≥ 20 mm that are located proximal to the splenic flexure and removed by electr…
View article: Assessment of Patient Referrals with Large Numbers of Non-pedunculated Colorectal Lesions
Assessment of Patient Referrals with Large Numbers of Non-pedunculated Colorectal Lesions Open
Background: Large (≥20mm) non-pedunculated colorectal lesions are frequently referred to specialty centers for endoscopic resection. These lesions are technically challenging to resectand associated with substantially greater risk than sma…
View article: 12 Month vs 6 Month Follow-up Colonoscopy After Piecemeal Endoscopic Resection of Large Nonpedunculated Colorectal Lesions
12 Month vs 6 Month Follow-up Colonoscopy After Piecemeal Endoscopic Resection of Large Nonpedunculated Colorectal Lesions Open
Background and aims:Current colonoscopy guidelines recommend nonpedunculated lesions ≥20mm in size and removed piecemeal should have follow-up colonoscopy in 6 months to ensure complete resection. Some data suggest that a 12-month follow-u…
View article: P477 Performance of bowel preparation quality scales in patients with Crohn’s disease
P477 Performance of bowel preparation quality scales in patients with Crohn’s disease Open
Background The performance of bowel preparation (BP) in patients with Crohn’s disease (CD) is unknown and may be suboptimal due to the presence of mucosal inflammation, strictures, pseudopolyps and bowel resection. We evaluated the reliabi…
View article: The Environmental Impact of Gastrointestinal Procedures: A Prospective Study of Waste Generation, Energy Consumption, and Auditing in an Endoscopy Unit
The Environmental Impact of Gastrointestinal Procedures: A Prospective Study of Waste Generation, Energy Consumption, and Auditing in an Endoscopy Unit Open
On average, every 100 GI endoscopy procedures (esophagogastroduodenoscopy/colonoscopy) are associated with 303 kg of solid waste and 1385 gallons of liquid waste generation, and 1980 kW·h energy consumption. Potentially recyclable material…
View article: Snare Tip Soft Coagulation vs Argon Plasma Coagulation vs No Margin Treatment After Large Nonpedunculated Colorectal Polyp Resection: a Randomized Trial
Snare Tip Soft Coagulation vs Argon Plasma Coagulation vs No Margin Treatment After Large Nonpedunculated Colorectal Polyp Resection: a Randomized Trial Open
In a randomized trial STSC and APC were each superior to no thermal margin treatment after EMR. STSC was faster to apply than APC. Because STSC also results in lower cost and plastic waste than APC (APC requires an additional device), our …
View article: One-device colonoscopy: feasibility, cost savings, and plastic waste reduction by procedure indication, when performed by a high detecting colonoscopist
One-device colonoscopy: feasibility, cost savings, and plastic waste reduction by procedure indication, when performed by a high detecting colonoscopist Open
Background Cold forceps and snares are each effective for removing polyps of 1–3 mm, while snares are more effective for polyps of 4–10 mm in size. If, in the same patient, polyps of 1–3 mm are removed with forceps and those of 4–10 mm wit…
View article: Frequency of serrated polyposis syndrome recognition by community endoscopists
Frequency of serrated polyposis syndrome recognition by community endoscopists Open
Background and study aims Some data indicate serrated polyposis syndrome (SPS) is underdiagnosed. We determined the frequency of SPS diagnosis by community endoscopists prior to referral to a tertiary center. Patients and methods We perfor…
View article: Higher Serrated Polyp Detection Rates Are Associated With Lower Risk of Postcolonoscopy Colorectal Cancer: Data From the New Hampshire Colonoscopy Registry
Higher Serrated Polyp Detection Rates Are Associated With Lower Risk of Postcolonoscopy Colorectal Cancer: Data From the New Hampshire Colonoscopy Registry Open
INTRODUCTION: We used New Hampshire Colonoscopy Registry data to examine the association between postcolonoscopy colorectal cancer (PCCRC) and sessile serrated detection rates (SSLDRs). METHODS: We included patients with either a colonosco…
View article: Data from Shifts in the Fecal Microbiota Associated with Adenomatous Polyps
Data from Shifts in the Fecal Microbiota Associated with Adenomatous Polyps Open
Background: Adenomatous polyps are the most common precursor to colorectal cancer, the second leading cause of cancer-related death in the United States. We sought to learn more about early events of carcinogenesis by investigating shifts …
View article: Supplementary Figure 3 from Genome-Wide Association Study Identifies Possible Genetic Risk Factors for Colorectal Adenomas
Supplementary Figure 3 from Genome-Wide Association Study Identifies Possible Genetic Risk Factors for Colorectal Adenomas Open
PDF file - 379K, GWAS SNP QC.
View article: Figure S2 from Shifts in the Fecal Microbiota Associated with Adenomatous Polyps
Figure S2 from Shifts in the Fecal Microbiota Associated with Adenomatous Polyps Open
Supplementary Figure 2. Heat map of significantly predictive taxa. Hierarchical clustering is based on the Euclidean distance of log proportion, complete linkage. The left cluster is enriched in adenoma samples (P=0.1, Fisher's exact test).
View article: Figure S3 from Shifts in the Fecal Microbiota Associated with Adenomatous Polyps
Figure S3 from Shifts in the Fecal Microbiota Associated with Adenomatous Polyps Open
Supplementary Figure 3. A receiver operating characteristic curve generated using the four significant taxa (Streptococcus, Veillonella, Mogibacterium, and Sutterella) identified by the random forests algorithm demonstrates a poor ability …
View article: Supplementary Figure 2 from Genome-Wide Association Study Identifies Possible Genetic Risk Factors for Colorectal Adenomas
Supplementary Figure 2 from Genome-Wide Association Study Identifies Possible Genetic Risk Factors for Colorectal Adenomas Open
PDF file - 244K, Concordance QC for the TCPS GWAS.