Donald M. Lloyd‐Jones
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View article: Association between cigarette smoking status, intensity, and cessation duration with long-term incidence of nine cardiovascular and mortality outcomes: The Cross-Cohort Collaboration (CCC)
Association between cigarette smoking status, intensity, and cessation duration with long-term incidence of nine cardiovascular and mortality outcomes: The Cross-Cohort Collaboration (CCC) Open
Background Uncertainties persist regarding the precise shape of the smoking-outcome curves across various cardiovascular and mortality endpoints. This study aims to elucidate the relationships among smoking burden, intensity, and cessation…
Mid- and late-life cardiovascular health indicators and changes in biological ageing Markers; a multi-cohort study Open
National Institute on Aging, National Heart, Lung, and Blood Institute, Icelandic Heart Association, and Italian Ministry of Health.
View article: Cardiovascular Health Changes in Young Adults and Risk of Later-Life Cardiovascular Disease
Cardiovascular Health Changes in Young Adults and Risk of Later-Life Cardiovascular Disease Open
Importance Associations of midlife cardiovascular health (CVH), measured once, with incident cardiovascular disease (CVD) are well described. Less is known about patterns of young adulthood CVH, including its changes and associations with …
View article: Long‐Term Blood Pressure Level and Variability From Midlife to Later Life and Subsequent Cognitive Change: The ARIC Neurocognitive Study
Long‐Term Blood Pressure Level and Variability From Midlife to Later Life and Subsequent Cognitive Change: The ARIC Neurocognitive Study Open
Background To understand how blood pressure ( BP ) from midlife and beyond is related to cognition in older age, a lifespan approach is needed. We assessed the associations of BP levels and variability from midlife on with subsequent cogni…
View article: Future of Families: Cardiovascular Health Among Young Adults Cohort Study: Rationale, Key Questions, Study Design, and Participant Characteristics
Future of Families: Cardiovascular Health Among Young Adults Cohort Study: Rationale, Key Questions, Study Design, and Participant Characteristics Open
Background Childhood social determinants of adult cardiovascular health and potential mechanisms that link them are poorly understood. The FF‐CHAYA (Future of Families–Cardiovascular Health Among Young Adults) study is designed to address …
View article: Use of Risk Assessment to Guide Decision-Making for Blood Pressure Management in the Primary Prevention of Cardiovascular Disease: A Scientific Statement From the American Heart Association and American College of Cardiology
Use of Risk Assessment to Guide Decision-Making for Blood Pressure Management in the Primary Prevention of Cardiovascular Disease: A Scientific Statement From the American Heart Association and American College of Cardiology Open
Risk assessment plays a central role in the primary prevention of cardiovascular disease. The 2017 High Blood Pressure Clinical Practice Guideline incorporated quantitative risk assessment for the first time to guide the initiation of anti…
View article: Use of Risk Assessment to Guide Decision-Making for Blood Pressure Management in the Primary Prevention of Cardiovascular Disease: A Scientific Statement From the American Heart Association and American College of Cardiology
Use of Risk Assessment to Guide Decision-Making for Blood Pressure Management in the Primary Prevention of Cardiovascular Disease: A Scientific Statement From the American Heart Association and American College of Cardiology Open
Risk assessment plays a central role in the primary prevention of cardiovascular disease. The 2017 High Blood Pressure Clinical Practice Guideline incorporated quantitative risk assessment for the first time to guide the initiation of anti…
View article: Comparing the “Life's Essential 8” Scores of Older Adults Living With Cardiovascular Diseases: NHANES, 2013 to 2018
Comparing the “Life's Essential 8” Scores of Older Adults Living With Cardiovascular Diseases: NHANES, 2013 to 2018 Open
Background The American Heart Association's Life's Essential 8 (LE8) framework quantifies cardiovascular health. Prior studies have focused on individuals without clinical cardiovascular disease (CVD). We sought to examine recent trends in…
View article: Statin Eligibility According to Atherosclerotic Cardiovascular Disease Risk in the US
Statin Eligibility According to Atherosclerotic Cardiovascular Disease Risk in the US Open
This cross-sectional study evaluates the implications of using the Predicting Risk of Cardiovascular Disease Events criteria to assess 10-year atherosclerotic cardiovascular disease risk estimates.
View article: 2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines Open
AIM: The “2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults” retires and replaces the “2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/A…
View article: 2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines Open
AIM: The “2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults” retires and replaces the “2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/A…
View article: PREVENT Risk Age Equations and Population Distribution in US Adults
PREVENT Risk Age Equations and Population Distribution in US Adults Open
This cross-sectional study describes the Predicting Risk of Cardiovascular Disease Events (PREVENT) risk age and its distribution among US adults.
View article: Dietary metabolic signatures and cardiometabolic risk
Dietary metabolic signatures and cardiometabolic risk Open
AIMS: Observational studies of diet in cardiometabolic-cardiovascular disease (CM-CVD) focus on self-reported consumption of food or dietary pattern, with limited information on individual metabolic responses to dietary intake linked to CM…
View article: Genome‐wide meta‐analysis of SNP and antihypertensive medication interactions on left ventricular traits in African Americans
Genome‐wide meta‐analysis of SNP and antihypertensive medication interactions on left ventricular traits in African Americans Open
BACKGROUND: Left ventricular (LV) hypertrophy affects up to 43% of African Americans (AAs). Antihypertensive treatment reduces LV mass (LVM). However, interindividual variation in LV traits in response to antihypertensive treatments exists…
View article: Cardiovascular Health, 2010 to 2020: A Systematic Review of a Decade of Research on Life's Simple 7
Cardiovascular Health, 2010 to 2020: A Systematic Review of a Decade of Research on Life's Simple 7 Open
Background In 2010, the American Heart Association introduced Life's Simple 7, a construct to measure, monitor, and modify cardiovascular health (CVH) across the lifespan. We aimed to summarize the knowledge on outcomes, prevalence, determ…
View article: Education, Race/Ethnicity, and Causes of Premature Mortality Among Middle-Aged Adults in 4 US Urban Communities: Results From CARDIA, 1985-2017.
Education, Race/Ethnicity, and Causes of Premature Mortality Among Middle-Aged Adults in 4 US Urban Communities: Results From CARDIA, 1985-2017. Open
Objectives. To assess causes of premature death and whether race/ethnicity or education is more strongly and independently associated with premature mortality in a diverse sample of middle-aged adults in the United States.Methods. The Coro…
View article: Association of multimorbidity trajectories from early adulthood through middle age with middle-age physical function
Association of multimorbidity trajectories from early adulthood through middle age with middle-age physical function Open
Background Chronic conditions can develop early in the adult life course and accumulate at different rates. However, the association between multimorbidity trajectory groups from young adulthood and physical function in midlife has not bee…
View article: Prepregnancy Cardiovascular Health, Gestational Diabetes, and Coronary Artery Calcium
Prepregnancy Cardiovascular Health, Gestational Diabetes, and Coronary Artery Calcium Open
Importance Poor cardiovascular health (CVH) and gestational diabetes (GD) are each associated with higher risk for cardiovascular disease (CVD). Individuals with poor CVH also have a higher risk of GD, but it remains unclear if GD mediates…
View article: A Bayesian approach for unadjudicated events in cardiovascular disease cohort studies
A Bayesian approach for unadjudicated events in cardiovascular disease cohort studies Open
An important issue in joint modelling for outcomes and longitudinal risk factors in cohort studies is to have an accurate assessment of events. Events determined based on ICD-9 codes can be very inaccurate, in particular for cardiovascular…
Association Between Life's Essential 8 and Cardiovascular, Cancer, and Other Cause Mortality Open
Better LE8-quantified CVH was associated with lower CVD and cancer mortality in a competing risk framework. These findings underscore the significance of lifestyle modifications in mortality risk reduction, advocating for their incorporati…