Explanipedia

Left atrioventricular valve durability in atrioventricular septal defects: Impact of systolic blood pressure Open

Christina L. Greene, Taddese Desta, A. Sharma, David Mauchley, Lyubomyr Bohuta , et al. · 2025

Left ventricular decompression in paediatric veno‐arterial extracorporeal life support: Reviewing the evidence Open

Giacomo Veronese, Paolo Meani, Domenico Sirico, Giovanni Di Salvo, Enrico Ammirati , et al. · 2025

Veno‐arterial extracorporeal life support (VA ECLS) is crucial for neonatal and paediatric patients with severe circulatory collapse but may cause left ventricular (LV) overload, affecting myocardial recovery and causing complications. Evi…

Significant reduction in blood product usage, same early outcomes: Blood conservation in infants undergoing open heart surgery Open

Lyubomyr Bohuta, Titus Chan, Kevin Charette, Gregory J. Latham, Christina L. Greene , et al. · 2024

Blood conservation is associated with significant reduction in usage of blood products during open heart surgery in infants with no significant effect on early outcomes. This trend is observed across all categories of surgical complexity. …

The Influence of the Extracorporeal Membrane Oxygenation Circuit and Components on Anticoagulation Management: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference Open

Adam S. Himebauch, John R. Priest, Gail M. Annich, D. Michael McMullan, David Turner , et al. · 2024

OBJECTIVES: To derive systematic-review informed, modified Delphi consensus regarding the influence of extracorporeal membrane oxygenation (ECMO) circuit components on anticoagulation practices for pediatric ECMO for the Pediatric ECMO Ant…

Executive Summary: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE (PEACE) Consensus Conference* Open

Peta Alexander, Melania M. Bembea, Katherine Cashen, Ira M. Cheifetz, Heidi J. Dalton , et al. · 2024

OBJECTIVES: To present recommendations and consensus statements with supporting literature for the clinical management of neonates and children supported with extracorporeal membrane oxygenation (ECMO) from the Pediatric ECMO Anticoagulati…

Randomized controlled trial of remote ischemic preconditioning in children having cardiac surgery Open

Yuk M. Law, Christine Hsu, Sangeeta Hingorani, Michael Richards, D. Michael McMullan , et al. · 2024

Background Children undergoing cardiac surgery are at risk for acute kidney injury (AKI) and cardiac dysfunction. Opportunity exists in protecting end organ function with remote ischemic preconditioning. We hypothesize this intervention le…

Safety and Efficacy of Extracorporeal Membrane Oxygenation Heating Units Open

Kyle S. Bilodeau, Kevin Charette, D. Michael McMullan · 2023

Background Patient temperature during extracorporeal membrane oxygenation (ECMO) is commonly managed by dedicated heating units (HUs) that are integrated into ECMO circuitry. Currently, no HU has received approval for ECMO by the FDA in th…

Discussion to: Surgical repair of neonatal total anomalous pulmonary venous connection: A single institutional experience with 241 cases Open

Guocheng Shi, D. Michael McMullan · 2023

Randomized Controlled Trial of Remote ISchemic Preconditioning in Children Having Cardiac Surgery Open

Yuk M. Law, Christine Hsu, Ronit Katz, Sangeeta Hingorani, Michael Richards , et al. · 2022

Background Children undergoing cardiac surgery are at risk for acute kidney injury (AKI) and cardiac dysfunction. Opportunity exists in protecting end organ function with remote ischemic preconditioning. We hypothesize this intervention le…

Ethical Considerations in Ever-Expanding Utilization of ECLS: A Research Agenda Open

Jonna D. Clark, H Baden, Emily Berkman, Erica Bourget, Thomas V. Brogan , et al. · 2022

Technological advancements and rapid expansion in the clinical use of extracorporeal life support (ECLS) across all age ranges in the last decade, including during the COVID-19 pandemic, has led to important ethical considerations. As a co…

Waitlist and posttransplant outcomes of critically ill infants awaiting heart transplantation managed without ventricular assist device support Open

E Frandsen, Katherine Banker, Robert Mazor, D. Michael McMullan, Yuk M. Law , et al. · 2022

Background Infants listed for heart transplant are at high risk for waitlist mortality. While waitlist mortality for children has decreased in the current era of increased ventricular assist device use, outcomes for small infants supported…

Factors Associated with Pediatric In-Hospital Recurrent Cardiac Arrest Open

Stephanie R. Brown, Joan Roberts, Elizabeth Y. Killien, Thomas V. Brogan, Reid Farris , et al. · 2022

The objective of this article was to identify demographic and clinical factors associated with early recurrent arrest (RA; <48 hours) and late RA (≥48 hours) among pediatric inpatients following an initial in-hospital cardiac arrest. A ret…

2020 EACTS/ELSO/STS/AATS expert consensus on post-cardiotomy extracorporeal life support in adult patients Open

Roberto Lorusso, Glenn Whitman, Milan Milojevic, Giuseppe Maria Raffa, D. Michael McMullan , et al. · 2020

2020 EACTS/ELSO/STS/AATS Expert Consensus on Post-Cardiotomy Extracorporeal Life Support in Adult Patients Open

Roberto Lorusso, Glenn Whitman, Milan Milojevic, Giuseppe Maria Raffa, D. Michael McMullan , et al. · 2020

2020 EACTS/ELSO/STS/AATS Expert Consensus on Post-cardiotomy Extracorporeal Life Support in Adult Patients Open

Roberto Lorusso, Glenn Whitman, Milan Milojevic, Giuseppe Maria Raffa, D. Michael McMullan , et al. · 2020

Post-cardiotomy extracorporeal life support (PC-ECLS) in adult patients has been used only rarely but recent data have shown a remarkable increase in its use, almost certainly due to improved technology, ease of management, growing familia…

A rare pediatric case of left ventricular outflow tract infective endocarditis in hypertrophic cardiomyopathy Open

Madonna E. Lee, Mariska Kemna, Amy Schultz, D. Michael McMullan · 2020

Central MessageA rare pediatric presentation of infectious endocarditis in hypertrophic obstructive cardiomyopathy necessitating surgery to address both pathologies.See Commentaries on pages 283, 285, and 286. A rare pediatric presentation…

2020 EACTS/ELSO/STS/AATS expert consensus on post-cardiotomy extracorporeal life support in adult patients Open

Roberto Lorusso, Glenn Whitman, Milan Milojevic, Giuseppe Maria Raffa, D. Michael McMullan , et al. · 2020

Post-cardiotomy extracorporeal life support (PC-ECLS) in adult patients has been used only rarely but recent data have shown a remarkable increase in its use, almost certainly due to improved technology, ease of management, growing familia…

Initial ELSO Guidance Document: ECMO for COVID-19 Patients with Severe Cardiopulmonary Failure Open

Robert H. Bartlett, Mark Ogino, Daniel Brodie, D. Michael McMullan, Roberto Lorusso , et al. · 2020

Disclaimer: ECMO has, and will certainly continue, to play a role in the management of COVID-19 patients. It should be emphasized that this initial guidance is based on the current best evidence for ECMO use during this pandemic. Guidance …

Increased Stroke Risk in Children and Young Adults on Extracorporeal Life Support with Carotid Cannulation Open

Jane L. Di Gennaro, Titus Chan, Reid Farris, Noel S. Weiss, D. Michael McMullan · 2019

Patients on extracorporeal life support (ECLS) are at risk for central nervous system (CNS) injury. One potentially modifiable risk factor is site of arterial cannulation in venoarterial (VA) ECLS, as in most cases one can choose the femor…

Extracorporeal life support in preoperative and postoperative heart transplant management Open

C. Bermúdez, D. Michael McMullan · 2017

Increased experience with extracorporeal life support (ECLS) as a mode of cardiac support has expanded its use to diverse patient populations including patients requiring a bridge to heart transplantation and patients requiring posttranspl…

Novel ECMO surgical cannulation simulators Open

D. Michael McMullan · 2017

Simulation training is increasingly being used to provide clinical care providers with experience and competence in high-risk procedures that occur infrequently. Implementation of standardized extracorporeal life support (ECLS) simulation …

Extracorporeal cardiopulmonary resuscitation Open

Nicholson Yam, D. Michael McMullan · 2017

Extracorporeal life support (ECLS) is used for patients in isolated or combined cardiopulmonary failures. The use of ECLS to rescue patients with cardiac arrest that is refractory to conventional cardiopulmonary resuscitation has been show…

Racial and Ethnic Variation in Pediatric Cardiac Extracorporeal Life Support Survival Open

Titus Chan, Jane Di Gennaro, Reid Farris, Monique Radman, D. Michael McMullan · 2017

Objectives: Previous studies have suggested an association between nonwhite race and poor outcomes in small subsets of cardiac surgery patients who require extracorporeal life support. This study aims to examine the association of race/eth…

Extracorporeal Life Support for Pediatric Heart Failure Open

Christopher R. Burke, D. Michael McMullan · 2016

Extracorporeal life support (ECLS) represents an essential component in the treatment of the pediatric patient with refractory heart failure. Defined as the use of an extracorporeal system to provide cardiopulmonary support, ECLS provides …

WITHDRAWN Open

Britton Keeshan, Gabrielle Vaughn, Matthew J. O’Connor, Kewen Lin, Robert E. Shaddy , et al. · 2015

Is Earlier Better? Influence of Timing of VAD Implantation on Post-Transplant Survival in Pediatric Cardiomyopathy Patients Open

Britton Keeshan, Gabrielle Vaughn, Matthew J. O’Connor, Kimberly Y. Lin, Robert E. Shaddy , et al. · 2015

Comparison of Transplant Waitlist Outcomes for Pediatric Candidates Supported By Ventricular Assist Devices vs. Medical Therapy Alone Open

Sabrina Law, Assaf P. Oron, Mariska Kemna, Erin L. Albers, D. Michael McMullan , et al. · 2015

Pre-Transplant Ventricular Assist Device Utilization Varies By Hospital Environment Open

Titus Chan, Mariska Kemna, Erin L. Albers, Borah Hong, Yuk M. Law , et al. · 2015

Fatal Spontaneous Dissection of a Contegra Conduit in a Child Open

Joshua D Weldin, Raj P. Kapur, Mark Lewin, D. Michael McMullan · 2015

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