Biswadev Mitra
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View article: Viscoelastic haemostatic assays in chronic liver disease—Profiling coagulation in the emergency department
Viscoelastic haemostatic assays in chronic liver disease—Profiling coagulation in the emergency department Open
Background and Objectives The role of viscoelastic haemostatic assays (VHAs) versus conventional coagulation tests (CCTs) in chronic liver disease (CLD) in the emergency department (ED) is undefined. We aimed to characterize VHA profiles a…
View article: The lethal triad in patients with severe burns
The lethal triad in patients with severe burns Open
A small proportion of patients with severe burns presented to hospital with all three components of the lethal triad of trauma. Acidemia and hypothermia were more commonly observed when compared to coagulopathy. Recognition, prevention, an…
View article: Stakeholder Perspectives of the Delivery of Tele-Emergency Care: Insights from the Southeast Melbourne Virtual Emergency Department
Stakeholder Perspectives of the Delivery of Tele-Emergency Care: Insights from the Southeast Melbourne Virtual Emergency Department Open
Background: Emergency department (ED) demand is increasing due to rising patient complexity and an aging population complicated by limited access to general practitioners. Virtual emergency departments (VEDs) have been proposed as an alter…
View article: Impact of different preferred functional outcomes on the results of the pre-hospital antifibrinolytics for traumatic coagulopathy and hemorrhage (PATCH-trauma) trial
Impact of different preferred functional outcomes on the results of the pre-hospital antifibrinolytics for traumatic coagulopathy and hemorrhage (PATCH-trauma) trial Open
The assessment of TXA therapy's efficacy and safety may vary depending on scenarios where certain functional outcomes are considered worse than death. This analytical approach could inform functional outcome assessment in future acute care…
View article: Antibiotic Therapy for Pyelonephritis in the Emergency Department
Antibiotic Therapy for Pyelonephritis in the Emergency Department Open
Objectives Acute pyelonephritis (APN) is a common diagnosis among patients presenting to the Emergency Department (ED). It is treated by empiric antibiotics within the ED. With a rise in antimicrobial resistance globally, it is unknown whe…
View article: The Viscoelastic Haemostatic Assay Landscape in Queensland, Australia: An Analysis of Use, Indications and Integration
The Viscoelastic Haemostatic Assay Landscape in Queensland, Australia: An Analysis of Use, Indications and Integration Open
Background Viscoelastic haemostatic assays ( VHAs ) guide transfusion decisions in bleeding patients. We assessed testing volumes, clinical indications and patient characteristics in a statewide population in Australia. Methods This retros…
View article: Reducing blood wastage through introduction of a transfusion team
Reducing blood wastage through introduction of a transfusion team Open
Background In the intense setting of reception and resuscitation of critically bleeding patients, wastage of up to 10% of blood components occur, commonly due to prolonged breaks in the cold chain. Additionally, some transfusions may be av…
View article: Tranexamic Acid Timing and Mortality Impact After Trauma
Tranexamic Acid Timing and Mortality Impact After Trauma Open
The optimal therapeutic window for TXA after trauma may be within 90 minutes.
View article: Presenting to emergency departments with functional seizures: Motivators for attendance and experiences of care
Presenting to emergency departments with functional seizures: Motivators for attendance and experiences of care Open
The minority of patients make the decision to seek emergency department care themselves with a functional seizure. Further education of ED professionals, including guidelines for screening and quality of care measures, could help to addres…
View article: Variability in viscoelastic haemostatic assay in major haemorrhage protocols: A unified approach or mixed signals?
Variability in viscoelastic haemostatic assay in major haemorrhage protocols: A unified approach or mixed signals? Open
Background and Objectives Viscoelastic haemostatic assays (VHA) are part of patient blood management (PBM) for bleeding, associated with reduced transfusions. This study reviewed all major haemorrhage protocols (MHPs) using VHA in Queensla…
View article: Coagulation and Transfusion Informatics in Chronic Liver Disease: A Data Linkage Study of Emergency Department Presentations
Coagulation and Transfusion Informatics in Chronic Liver Disease: A Data Linkage Study of Emergency Department Presentations Open
Objective To describe the application of data linkage for analysing coagulation abnormalities and blood transfusion practices in patients with chronic liver disease (CLD) presenting to emergency departments (EDs). Methods Patients with CLD…
View article: Core outcome set for research in necrotising soft tissue infection patients: an international, multidisciplinary, modified Delphi consensus study
Core outcome set for research in necrotising soft tissue infection patients: an international, multidisciplinary, modified Delphi consensus study Open
Introduction: Necrotising soft tissue infections (NSTI) are serious infections associated with considerable morbidity and mortality. Heterogeneity of outcome reporting in the NSTI literature precludes the synthesis of high-quality evidence…
View article: P-338 Impact of Endometriosis on IVF Outcomes: A Comprehensive Review of Ovarian Stimulation, Pre-treatment Strategies, and Adjunctive Therapies
P-338 Impact of Endometriosis on IVF Outcomes: A Comprehensive Review of Ovarian Stimulation, Pre-treatment Strategies, and Adjunctive Therapies Open
Study question How does endometriosis affect IVF outcomes, and can novel approaches like Elagolix improve key fertility parameters and cumulative live birth rates Summary answer Endometriosis variably affects IVF success, with Elagolix and…
View article: The incidence and determinants of traumatic brain injury deaths occurring outside hospital in Australia
The incidence and determinants of traumatic brain injury deaths occurring outside hospital in Australia Open
Objective To identify the determinants of death occurring outside of hospital following moderate to severe traumatic brain injury (msTBI) across Australia. Methods Design, setting: Retrospective observational study using National Coronial …
View article: Effectiveness of inhaled methoxyflurane in acute pain in an emergency department – A systematic review of randomized controlled trials
Effectiveness of inhaled methoxyflurane in acute pain in an emergency department – A systematic review of randomized controlled trials Open
Inhaled methoxyflurane provides rapid and effective pain relief for acute trauma, consistently outperforming placebo and standard treatments and improving patient and clinician satisfaction.
View article: Imaging for older patients with head impact at baseline conscious state
Imaging for older patients with head impact at baseline conscious state Open
Objective To describe CT brain (CTB) and neurosurgical management among head injured patients aged ≥ 85 years and minimal or no change in Glasgow Coma Scale (GCS). Methods A retrospective cohort study was undertaken using radiology and adm…
View article: Evaluating the satisfaction of patients utilising the virtual emergency department service in southeast region of Melbourne
Evaluating the satisfaction of patients utilising the virtual emergency department service in southeast region of Melbourne Open
Objectives Evaluate patient satisfaction with paramedic and residential aged care facility (RACF) staff‐initiated tele‐emergency care through the Southeast Melbourne Virtual ED. Methods Patient satisfaction surveys were conducted across tw…
View article: The CSF-serum albumin quotient as a biomarker of severe traumatic brain injury: A pilot study
The CSF-serum albumin quotient as a biomarker of severe traumatic brain injury: A pilot study Open
Background: Severe traumatic brain injury (TBI) can disrupt blood–brain barrier permeability and increase transfer of albumin from the serum to the cerebrospinal fluid (CSF). A high CSF/serum albumin quotient (QAlb) is a biomarker for bloo…
View article: Evaluating the utility of chest x-rays for non-traumatic chest pain in Australia- a retrospective cohort study
Evaluating the utility of chest x-rays for non-traumatic chest pain in Australia- a retrospective cohort study Open
Purpose The aim of this study was to quantify the proportion of chest x-rays (CXRs) for non-traumatic chest pain (NTCP) in the emergency department (ED) that were abnormal and assess the clinical significance of these abnormalities. We als…
View article: The determinants for death in hospital following moderate to severe traumatic brain injury in Australia
The determinants for death in hospital following moderate to severe traumatic brain injury in Australia Open
Objectives To establish the determinants of death in hospital for patients with moderate to severe traumatic brain injury (TBI) in Australia. Design, setting, participants Retrospective analysis of Australia New Zealand Trauma Registry (AN…
View article: Rate and yield of imaging for acute pyelonephritis in the emergency department: A retrospective cohort study
Rate and yield of imaging for acute pyelonephritis in the emergency department: A retrospective cohort study Open
Objectives The role of imaging in acute pyelonephritis (APN) in the ED is poorly understood, with variability among clinical guidelines for when patients should be imaged, and the modality of imaging. The objective of this study was to ide…
View article: Research outputs after the Coursework Pathway
Research outputs after the Coursework Pathway Open
Objectives The aim of the present study was to quantify research outputs after completing a Coursework Pathway (CP). Methods Emergency medicine trainees who completed a CP during 2012–2022 were included. Research outputs were identified us…
View article: Lessons from surge disaster response simulation activities
Lessons from surge disaster response simulation activities Open
Purpose: Emergency Departments (ED) play a sentinel role in disaster responses, from decontamination and triage to stabilisation of patients, while continuing to provide routine medical care for existing and new patients. However, the low …