Masahiro Mori
YOU?
Author Swipe
View article: MRI-negative myelitis, especially after COVID-19: a case report and literature review
MRI-negative myelitis, especially after COVID-19: a case report and literature review Open
Background Neurological sequelae of coronavirus disease 2019 (COVID-19) include inflammatory myelopathies. Among these, magnetic resonance imaging (MRI)-negative myelitis— defined as normal spinal cord MRI findings despite compatible clini…
View article: Elevated serum levels of C-terminal agrin fragment in acetylcholine receptor antibody-positive myasthenia gravis
Elevated serum levels of C-terminal agrin fragment in acetylcholine receptor antibody-positive myasthenia gravis Open
Agrin is essential for neuromuscular junction (NMJ) formation and maintenance. The C-terminal agrin fragment (CAF), generated by neurotrypsin-mediated cleavage of agrin, has been gaining attention as a potential biomarker for sarcopenia. W…
View article: Complete genome sequence of <i>Edwardsiella tarda</i> strain GBS0709 isolated from a Japanese patient with the acute motor axonal neuropathy subtype of Guillain–Barré syndrome
Complete genome sequence of <i>Edwardsiella tarda</i> strain GBS0709 isolated from a Japanese patient with the acute motor axonal neuropathy subtype of Guillain–Barré syndrome Open
The complete genome sequence of Edwardsiella tarda strain GBS0709, isolated from an 81-year-old Japanese patient with the acute motor axonal neuropathy subtype of Guillain–Barré syndrome, was determined. It comprised a 3,632,068 bp circula…
View article: Effects of Denosumab and Bisphosphonates on Glucocorticoid-induced Osteoporosis in Patients with Neuroimmunological Disorders
Effects of Denosumab and Bisphosphonates on Glucocorticoid-induced Osteoporosis in Patients with Neuroimmunological Disorders Open
Objective Although patients with neuroimmunological disorders often need to be treated with glucocorticoids and are at risk of developing glucocorticoid-induced osteoporosis, no research has focused on the treatment of glucocorticoid-induc…
View article: Age-Dependent Changes in Effective Dose in Pediatric Brain CT: Comparisons of Estimation Methods
Age-Dependent Changes in Effective Dose in Pediatric Brain CT: Comparisons of Estimation Methods Open
The effective dose (ED) in computed tomography (CT) may be calculated by multiplying the dose–length product (DLP) by a conversion factor. As children grow, automatic exposure control increases the DLP, while the conversion factor decrease…
View article: Digital motor biomarkers of cerebellar ataxia using an RGB-depth camera-based motion analysis system
Digital motor biomarkers of cerebellar ataxia using an RGB-depth camera-based motion analysis system Open
This study aimed to identify quantitative biomarkers of motor function for cerebellar ataxia by evaluating gait and postural control using an RGB-depth camera-based motion analysis system. In 28 patients with degenerative cerebellar ataxia…
View article: Elevated serum levels of bone morphogenetic protein-9 are associated with better outcome in AQP4-IgG seropositive NMOSD
Elevated serum levels of bone morphogenetic protein-9 are associated with better outcome in AQP4-IgG seropositive NMOSD Open
Lymphatic drainage in the central nervous system is regulated by meningeal lymphatic vasculature, and recurrent neuroinflammation alters lymphatic vessel remodeling. Patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum…
View article: Cell-based flow cytometry assay for simultaneous detection of multiple autoantibodies in a single serum sample
Cell-based flow cytometry assay for simultaneous detection of multiple autoantibodies in a single serum sample Open
Accurate serologic evaluation of autoantibodies in patients with autoimmune diseases is critical. In the present study, we established a live cell-based assay for simultaneous detection of multiple autoantibodies in a single serum sample. …
View article: Complete Relief of Painful Tonic Seizures in Neuromyelitis Optica Spectrum Disorder by Satralizumab Treatment
Complete Relief of Painful Tonic Seizures in Neuromyelitis Optica Spectrum Disorder by Satralizumab Treatment Open
Satralizumab, a monoclonal antibody against interleukin-6 receptors, has been approved for the treatment of neuromyelitis optica spectrum disorder (NMOSD). Several reports have described the effectiveness of satralizumab against neuropathi…
View article: COVID-19 vaccination: effective utilization of low dead space (LDS) syringes
COVID-19 vaccination: effective utilization of low dead space (LDS) syringes Open
•In maximally utilizing COVID vaccine, syringes with low dead space (LDS) are required.•We employed insulin LDS syringes, when no suitable syringes were procured.•US assessment of subcutaneous fat thickness prior to inoculation was perform…
View article: Impact of Visceral Fat On The Prognosis of Coronavirus Disease 2019: An Observational Cohort Study
Impact of Visceral Fat On The Prognosis of Coronavirus Disease 2019: An Observational Cohort Study Open
Background Clarification of the risk factors for coronavirus disease 2019 (COVID-19) severity is strongly warranted for global health. Recent studies have indicated that elevated body mass index (BMI) is associated with unfavorable progres…
View article: Silent progression of brain atrophy in aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder
Silent progression of brain atrophy in aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder Open
Objective To investigate longitudinal brain atrophy in patients with neuromyelitis optica spectrum disorder (NMOSD). Methods We investigated the longitudinal brain atrophy rate in patients with aquaporin-4 antibody-positive NMOSD (AQP4+NMO…
View article: Cryptococcal Meningitis in a Fingolimod-Treated Patient
Cryptococcal Meningitis in a Fingolimod-Treated Patient Open
Repeated cryptococcal antigen testing in patients with multiple sclerosis who have been treated with fingolimod may facilitate early detection of cryptococcal meningitis.
View article: AQP4-IgG autoimmunity in Japan and Germany: Differences in clinical profiles and prognosis in seropositive neuromyelitis optica spectrum disorders
AQP4-IgG autoimmunity in Japan and Germany: Differences in clinical profiles and prognosis in seropositive neuromyelitis optica spectrum disorders Open
Background Clinical outcomes in neuromyelitis optica spectrum disorders (NMOSD) vary across different regions. Objective To describe clinical profiles in Japanese and German NMOSD patients. Methods Medical records of aquaporin-4-immunoglob…
View article: Cultural bias in motor function patterns: Potential relevance for predictive, preventive, and personalized medicine
Cultural bias in motor function patterns: Potential relevance for predictive, preventive, and personalized medicine Open
Background Quantification of motor performance has a promising role in personalized medicine by diagnosing and monitoring, e.g. neurodegenerative diseases or health problems related to aging. New motion assessment technologies can evolve i…
View article: Cognitive Impairment in Multiple System Atrophy Is Related to White Matter Damage Detected by the T1-Weighted/T2-Weighted Ratio
Cognitive Impairment in Multiple System Atrophy Is Related to White Matter Damage Detected by the T1-Weighted/T2-Weighted Ratio Open
Introduction: This study aimed to use a novel MRI contrast, the standardized T1-weighted/T2-weighted (sT1w/T2w) ratio, to assess damage of the white matter and gray matter in multiple system atrophy (MSA). Furthermore, this study investiga…
View article: Serum anti‐LRPAP1 is a common biomarker for digestive organ cancers and atherosclerotic diseases
Serum anti‐LRPAP1 is a common biomarker for digestive organ cancers and atherosclerotic diseases Open
Some cancers are related to atherosclerotic diseases; therefore, these two types of disease may share some antibody biomarkers in common. To investigate this, a first screening of sera was performed from patients with esophageal squamous c…
View article: Serum Sphingosine 1-Phosphate (S1P): A Novel Diagnostic Biomarker in Early Acute Ischemic Stroke
Serum Sphingosine 1-Phosphate (S1P): A Novel Diagnostic Biomarker in Early Acute Ischemic Stroke Open
Background: Sphingosine 1-phosphate (S1P) is a lipid metabolite that mediates various physiological processes, including vascular endothelial cell function, inflammation, coagulation/thrombosis, and angiogenesis. As a result, S1P may contr…
View article: Difference in fatigue and pain between neuromyelitis optica spectrum disorder and multiple sclerosis
Difference in fatigue and pain between neuromyelitis optica spectrum disorder and multiple sclerosis Open
The origin of fatigue may be associated with spinal cord lesions causing pain in NMOSD patients, but with brain lesions in MS patients.
View article: Peroxiredoxins are involved in the pathogenesis of multiple sclerosis and neuromyelitis optica spectrum disorder
Peroxiredoxins are involved in the pathogenesis of multiple sclerosis and neuromyelitis optica spectrum disorder Open
Peroxiredoxins (PRXs) are intracellular antioxidative enzymes but work as inflammatory amplifiers under the extracellular condition. To date, the function of PRXs in the pathogenesis of multiple sclerosis (MS) and neuromyelitis optica spec…
View article: Efficacy and Safety of Rituximab in Refractory CIDP With or Without IgG4 Autoantibodies (RECIPE): Protocol for a Double-Blind, Randomized, Placebo-Controlled Clinical Trial
Efficacy and Safety of Rituximab in Refractory CIDP With or Without IgG4 Autoantibodies (RECIPE): Protocol for a Double-Blind, Randomized, Placebo-Controlled Clinical Trial Open
Background Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune-mediated peripheral neuropathy that is currently classified into several clinical subtypes, which are presumed to have different pathogenic mechanisms…
View article: Real-time cholesterol sorting in Plasmodium falciparum-erythrocytes as revealed by 3D label-free imaging
Real-time cholesterol sorting in Plasmodium falciparum-erythrocytes as revealed by 3D label-free imaging Open
Cholesterol, a necessary component of animal cell membranes, is also needed by the lethal human malaria parasite Plasmodium falciparum . Because P. falciparum lacks a cholesterol synthesis pathway and malaria patients have low blood choles…
View article: Addition Effect of Poly(<i>N</i>-Vinyl Pyrrolidone) on the Miscibility of Cellulose Acetate/Poly(Vinyl Alcohol) Blends
Addition Effect of Poly(<i>N</i>-Vinyl Pyrrolidone) on the Miscibility of Cellulose Acetate/Poly(Vinyl Alcohol) Blends Open
Uniform mixing of cellulose acetate (CA) of DS (degree of substitution) = 2.18 with poly(vinyl alcohol) (PVA) was attained, by taking into consideration the hydrogen-bonding formability of both components. Blend miscibility of CA/PVA binar…