Dmitry O. Ivanov
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View article: Clinical and genetic characteristics of mucopolysaccharidosis type VI according to the Russian registry
Clinical and genetic characteristics of mucopolysaccharidosis type VI according to the Russian registry Open
BACKGROUND Mucopolysaccharidosis type VI (MPS VI) is a chronic, progressive, inherited disease with multiorgan involvement and a restricted life expectancy. AIM To investigate the epidemiological, clinical, and genetic characteristics of p…
View article: Juvenile arthritis damage index predicts poor response to biological treatment: A prospective cohort study
Juvenile arthritis damage index predicts poor response to biological treatment: A prospective cohort study Open
BACKGROUND Juvenile arthritis damage index (JADI) is a tool that measures the degree of aggressiveness of the juvenile idiopathic arthritis (JIA) course and assesses articular [JADI - articular damage (JADI-A)] and extraarticular [JADI - e…
View article: Attitudes Among Pediatric Gastroenterologists Toward Vaccination Based on an Anonymous Online Survey
Attitudes Among Pediatric Gastroenterologists Toward Vaccination Based on an Anonymous Online Survey Open
Background: Children with inflammatory bowel disease (IBD) are at heightened risk for vaccine-preventable infections because of underlying immune dysregulation and long-term immunosuppressive therapy. Despite published guidelines affirming…
View article: A case of thyroid hormone resistance syndrome due to previously undescribed mutation in the THRA gene
A case of thyroid hormone resistance syndrome due to previously undescribed mutation in the THRA gene Open
Thyroid hormone resistance (THR) syndrome is characterized by decreased sensitivity of peripheral tissues to active forms of thyroid hormones. We present a clinical case of a patient, demonstrating symptoms of hypothyroidism while having s…
View article: Predictors of lethal outcome in patients with immunoinflammatory diseases hospitalized in the intensive care unit
Predictors of lethal outcome in patients with immunoinflammatory diseases hospitalized in the intensive care unit Open
BACKGROUND Systemic immunoinflammatory diseases can affect multiple systems and organs. They have a severe course and severe complications, causing multiple organ failure and death. Quite often these patients are required to be hospitalize…
View article: Neonatal thyrotoxicosis: clinical features, diagnosis and treatment
Neonatal thyrotoxicosis: clinical features, diagnosis and treatment Open
Neonatal thyrotoxicosis is a rare life-threatening disease characterized by the development of hyperthyroidism symptoms in newborns. In most cases, neonatal thyrotoxicosis occurs in children of mothers with recurrent diffuse toxic goiter a…
View article: Familial Case of Morris Syndrome: Clinical Observations
Familial Case of Morris Syndrome: Clinical Observations Open
Hormonal regulation plays a crucial role in human sexual development. Mutations in the androgen receptor gene may cause peripheral androgen resistance, leading to characteristic phenotypic manifestations. In complete androgen resistance, p…
View article: Attitudes of pediatric gastroenterologists, rheumatologists and parents to vaccination based on an anonymous online survey
Attitudes of pediatric gastroenterologists, rheumatologists and parents to vaccination based on an anonymous online survey Open
Differences in vaccination coverage among patients with IBD, JIA, and healthy children, as well as to identify differences in vaccination attitudes between parents and physicians, including barriers and facilitators of immunization were as…
View article: Analysis of fatal outcomes of patients with mucopolysaccharidosis type II according to the Russian mucopolysaccharidosis registry
Analysis of fatal outcomes of patients with mucopolysaccharidosis type II according to the Russian mucopolysaccharidosis registry Open
BACKGROUND Mucopolysaccharidosis type II (MPS II) is a chronic inherited disease with multiorgan involvement, a progressive course, and restricted life expectancy. AIM To evaluate the predictors of fatal outcomes in MPS II patients. METHOD…
View article: Prognostic potential of hematological inflammatory indexes for in vitro fertilization
Prognostic potential of hematological inflammatory indexes for in vitro fertilization Open
The problem of infertility now is relevant and has high social significance both for the Russian Federation and for many other countries, due to its widespread occurrence. Overcoming infertility with in vitro fertilization (IVF) is still a…
View article: The heroism of Leningrad Pediatric Medical Institute staff in the Great Patriotic War
The heroism of Leningrad Pediatric Medical Institute staff in the Great Patriotic War Open
Year 2025 has been declared in Russia as the Year of the 80th Victory anniversary in the Great Patriotic War. Numerous documentary and literary works have been dedicated to the heroic efforts of medical personnel during the war and the Sie…
View article: Occupational stress as a risk factor for cardiovascular accidents in medical staff of anesthesiology and intensive care units (review)
Occupational stress as a risk factor for cardiovascular accidents in medical staff of anesthesiology and intensive care units (review) Open
Introduction. Occupational stress is one of the most common causes of cardiovascular catastrophe among emergency response personnel. The objective was to analyze the literature sources on assessing the level of stress and its impact on hea…
View article: Analysis of risk factors for lethal outcome in patients of pediatric intensive care units with immuno-inflammatory diseases
Analysis of risk factors for lethal outcome in patients of pediatric intensive care units with immuno-inflammatory diseases Open
Introduction. Systemic immune-inflammatory diseases can affect many systems and organs and have an extremely severe course with complications, causing multiple organ failure and death. Often, children with such diseases require hospitaliza…
View article: Level of Asthenia and Life Quality among Students during the COVID-19 Second Wave in the Russian Federation
Level of Asthenia and Life Quality among Students during the COVID-19 Second Wave in the Russian Federation Open
Introduction The COVID-19 pandemic significantly impacted the population in Russia, particularly students, who were forced to radically restructure their daily lives rhythm due to the introduction of distance learning, more homework, incre…
View article: Quality of Life and Behavioural Self-Regulation Style in Different Groups of the Russian Population during the Second Wave of COVID-19
Quality of Life and Behavioural Self-Regulation Style in Different Groups of the Russian Population during the Second Wave of COVID-19 Open
Introduction Quality of life (QoL) is a comprehensive concept encompassing an individual’s satisfaction with various aspects of life, including material, social, spiritual needs, intellectual and physical development, and safety. During th…
View article: Quality of Life, Depression, Anxiety, and Stress in Humanities Students and People living with HIV in Russia during the COVID-19 Second Wave
Quality of Life, Depression, Anxiety, and Stress in Humanities Students and People living with HIV in Russia during the COVID-19 Second Wave Open
Introduction During the pandemic of a new coronavirus infection in Russia, the number of patients with diagnosed depressive and anxiety disorders increased. Studies have shown a sharp increase in the number of respondents who recorded stre…
View article: Self-Regulation Behavioural Style and Emotional State in Students and People Living with HIV during the COVID-19 Second Wave in the Russian Federation
Self-Regulation Behavioural Style and Emotional State in Students and People Living with HIV during the COVID-19 Second Wave in the Russian Federation Open
Introduction Self-regulation refers to a structured mental process for initiating, organizing, maintaining, and managing internal and external activities directed toward achieving goals. Each individual exhibits a unique self-regulation st…
View article: Difficulties in diagnosing infectious diseases in children in outpatient settings
Difficulties in diagnosing infectious diseases in children in outpatient settings Open
Infectious diseases occupy a leading place in the pathology of children and adolescents, accounting for 70–80% of the structure of morbidity and causes of mortality. Underestimation of clinical manifestations of infectious diseases by pedi…
View article: The Features of Children with Juvenile Idiopathic Arthritis with Cervical Spine Involvement in the Data from a Retrospective Study Cohort
The Features of Children with Juvenile Idiopathic Arthritis with Cervical Spine Involvement in the Data from a Retrospective Study Cohort Open
Background/Objectives: Cervical spine arthritis (CSA) in children with juvenile idiopathic arthritis (JIA) can lead to clinically significant and irreversible functional impairment. Our study aimed to evaluate the features of the JIA disea…
View article: Erb palsy due to birth injury (a draft of the clinical recommendations)
Erb palsy due to birth injury (a draft of the clinical recommendations) Open
The article presents a draft of clinical recommendations for the diagnosis and treatment of Erb palsy in birth injury. These recommendations are intended for physicians of maternity hospitals and are aimed at providing information support …
View article: Sepsis in newborns (Draft federal guidelines)
Sepsis in newborns (Draft federal guidelines) Open
Neonatal sepsis is one of the most severe diseases of the neonatal period with a high probability of developing multiple organ dysfunction, septic shock and an unfavorable outcome. The purpose of this publication is to present draft federa…
View article: Practical recommendations for neonatologists and pediatricians “Congenital ureaplasma, mycoplasma and chlamidia infections” (Draft of clinical recommendations for discussion by specialists)
Practical recommendations for neonatologists and pediatricians “Congenital ureaplasma, mycoplasma and chlamidia infections” (Draft of clinical recommendations for discussion by specialists) Open
Congenital chlamydia infection develops as a result of the intranatal transmission of the pathogen Chlamydia trachomatis from mother to fetus, more often occurs in the form of conjunctivitis, symptoms of which appear in the second to third…
View article: Risk Factors for Surgical Site Infection After Cardiac Surgery in Neonates: A Case–Control Study
Risk Factors for Surgical Site Infection After Cardiac Surgery in Neonates: A Case–Control Study Open
Objectives: This study was undertaken to determine the incidence and risk factors associated with the development of sternal wound infection in neonates after surgery for congenital heart disease. Methods: A case–control study was conducte…
View article: Frequency of postoperative complications and level of quality of life in breast cancer patients during constructive plastic surgery depending on the type of implant
Frequency of postoperative complications and level of quality of life in breast cancer patients during constructive plastic surgery depending on the type of implant Open
Background . In recent years, the availability of reconstructive plastic surgery has reached a new level. when performing an oncological operation, the question arises about choosing further reconstruction tactics: through one-stage or thr…
View article: Clinical case, dynamics of the disease in a patient with Emery–Dreyfus muscular dystrophy caused by a mutation in the <i>SYNE2</i> gene
Clinical case, dynamics of the disease in a patient with Emery–Dreyfus muscular dystrophy caused by a mutation in the <i>SYNE2</i> gene Open
Emery–Dreyfus muscular dystrophy is a genetically heterogeneous disease with X-linked recessive, autosomal dominant and autosomal recessive forms, which can be caused by mutations in the EMD, LMNA, SYNE1 and SYNE2 genes. Emery–Dreyfus musc…
View article: Diagnosis and treatment of infection specific to the perinatal period (Draft clinical recommendations for discussion by neonatologists and pediatricians)
Diagnosis and treatment of infection specific to the perinatal period (Draft clinical recommendations for discussion by neonatologists and pediatricians) Open
Perinatal infections occupy a leading place among the causes of neonatal morbidity, maternal and perinatal mortality. Infections are among the main causes of termination of pregnancy and premature birth. The practical recommendations prese…
View article: Aleksander F. Tur — outstanding pediatrician, scientist, teacher (on the 130th anniversary of birth)
Aleksander F. Tur — outstanding pediatrician, scientist, teacher (on the 130th anniversary of birth) Open
In 2024, the medical community will celebrate the 130th anniversary of the birth of the outstanding pediatrician, scientist, creator of scientific and practical schools of pediatrics — Alexander F. Tur. Alexander F. Tur was born on Septemb…