Explanipedia

Vascular anatomy of L1 vertebral body in Wistar rat—corrosion-fluorescence, diaphanization and histological analysis, comparison to humans, and importance in blood supply-related investigation Open

Diogo Lino Moura, Diogo Casal, Sara Alves, Décio dos Santos Pinto Júnior, Maria de Lourdes Peres Novo , et al. · 2025

The vascular architecture of the L1 vertebral body in Wistar rats shows strong similarity to that of humans. These findings support the Wistar rat as a valid model for future studies on vertebral body vascularization and the role of ischem…

The healing process of vertebral body fracture in Wistar rats: creation of an animal model and demonstration of the impact of anterolateral vascularization disruption on bone healing Open

Diogo Lino Moura, Diogo Casal, Sara Alves, Rui Almeida, Diogo Pais , et al. · 2025

Disruption of the anterolateral vascular supply significantly delays healing in L1 vertebral body fractures in rats, evidenced by slower phase transitions and reduced bone maturation. These findings underscore the essential role of vascula…

Review of Piezoelectrical Materials Potentially Useful for Peripheral Nerve Repair Open

Diogo Casal, Maria Helena Casimiro, L.M. Ferreira, João Paulo Leal, Gabriela Rodrigues , et al. · 2023

It has increasingly been recognized that electrical currents play a pivotal role in cell migration and tissue repair, in a process named “galvanotaxis”. In this review, we summarize the current evidence supporting the potential benefits of…

The legal and ethical framework governing body donation in Europe – 2nd update on current practice Open

Erich Brenner, Ronald L. A. W. Bleys, Raffaele De, Ilia Catereniuc, A.R.M. Chirculescu , et al. · 2023

We still see that a clear and rigorous legal framework is still unavailable in several countries. We found national regulations in 18 out of 39 countries; two others have at least federal laws. Several countries accept not only donated bod…

Advanced laparoscopic surgical training using the Goyri-O’Neill perfusion technique of cadaveric embalming Open

T. Oliveira, Nuno Domingues, Artur Palmas, C.S. Biyani, Diogo Pais , et al. · 2023

OC-068 PORTUGUESE NATIONAL TRAINING IN HERNIA AND ABDOMINAL WALL SURGERY – THE RESIDENTS’ PERSPECTIVE Open

Diogo Pais, Joana Bolota, Alesandra Barreira, C Rolo Santos, Rui Alves , et al. · 2023

Abdominal Wall surgery is often considered the initial step in the training of General Surgery residents. However, that training is not standardized. The resident committee of the Portuguese Society of Hernia and Abdominal Wall (SPHPA) con…

ACHADOS ANATÔMICOS INVULGARES EM CRÂNIOS HUMANOS E RESPETIVAS APLICAÇÕES CLÍNICAS Open

Maria Alexandre Bettencourt Pires, Edivaldo Xavier da Silva Júnior, Ana Rita Rodrigues Póvoa, George Triantafyllou, J. Romero Sousa-Junior , et al. · 2023

ESTUDO DE CASO: No decurso das aulas tutoriais regulares para estudantes de Medicina da Nova Medical School de Lisboa, deparámo-nos com uma variação anatômica peculiar, numa das bases de crânio em que se detetava um forame oval duplicado. …

Chitosan-Based Membranes for Skin Wound Repair in a Dorsal Fold Chamber Rat Model Open

Maria Helena Casimiro, L.M. Ferreira, Pedro M.P. Santos, João Paulo Leal, Gabriela Rodrigues , et al. · 2022

Frequently, deep partial and full-thickness skin wounds do not spontaneously regenerate. To restore the normal function of skin, epidermal and dermal components have to be supplied to the wound bed by grafting various substrates. Available…

Evaluation of different analytical approaches using total reflection X-ray fluorescence systems for multielemental analysis of human tissues with different adipose content Open

Patrícia M. Carvalho, Eva Marguí, A. Kubala‐Kukuś, D. Banaś, Jorge Machado , et al. · 2022

Elemental content plays an important role in biological processes, and so, the multielemental analysis of human tissue samples is required in biomedical research. Still, the small amount of available biological samples and the adipose cont…

Molecular Changes In Cardiac Tissue As A New Marker To Predict Cardiac Dysfunction Induced By Radiotherapy Open

Sônia Machado Rocha Ribeiro, Ana Rita Simões, Filipe Rocha, Inês Sofia Vala, Ana Teresa Pinto , et al. · 2022

The contribution of radiotherapy, per se , to late cardiotoxicity remains controversial. To clarify its impact on the development of early cardiac dysfunction, we developed an experimental model in which the hearts of rats were exposed, in…

XXVII INTERNATIONAL SYMPOSIUM ON MORPHOLOGICAL SCIENCES “CELL, TISSUE, ORGANS – EXPERIENCE, INNOVATION AND PROGRESS” Open

Diogo Pais, Gulshat Kulniyazova, A. Alibekova · 2021

Modern science is developing at a rapid pace and today, especially during the epidemic situation, scientific events are in demand, which allow us to consider topical issues that interest participants from different areas, individual ways t…

Cancer During Pregnancy: How to Handle the Bioethical Dilemmas?—A Scoping Review With Paradigmatic Cases-Based Analysis Open

Diogo Alpuim Costa, José Guilherme Nobre, Susana Baptista de Almeida, Marisa Horta Ferreira, Inês Gonçalves , et al. · 2020

Ethical issues that arise during the care of a pregnant woman with cancer are challenging to physicians, policymakers, lawyers, and the bioethics community. The main purpose of this scoping review is to summarize existing literature regard…

Energy dispersive X-ray fluorescence quantitative analysis of biological samples with the external standard method Open

Patrícia M. Carvalho, Sofia Pessanha, Jorge Machado, A.L.M. Silva, J.F.C.A. Veloso , et al. · 2020

Functional and Physiological Methods of Evaluating Median Nerve Regeneration in the Rat Open

Diogo Casal, Eduarda Mota‐Silva, Inês Iria, Diogo Pais, Ana Farinho , et al. · 2020

The main goal of this investigation is to show how to create and repair different types of median nerve (MN) lesions in the rat. Moreover, different methods of simulating postoperative physiotherapy are presented. Multiple standardized str…

BD-2 and BD-3 increase skin flap survival in a model of ischemia and Pseudomonas aeruginosa infection Open

Diogo Casal, Inês Iria, José S. Ramalho, Sara Alves, Eduarda Mota‐Silva , et al. · 2019

Unconventional Perfusion Flaps in the Experimental Setting: A Systematic Review and Meta-Analysis Open

Diogo Casal, David Tanganho, Teresa Da Cunha, Eduarda Mota‐Silva, Inês Iria , et al. · 2019

Background: Unconventional perfusion flaps offer multiple potential advantages compared with traditional flaps. Although there are numerous experimental articles on unconventional perfusion flaps, the multiple animal species involved, the …

Rewards to increase living kidney donation: The state of the art Open

Sara Querido, André Weigert, Teresa Adragão, Domingos Machado, Diogo Pais · 2019

Rewards to increase living kidney donation: The state of the art Open

Sara Querido, André Weigert, Teresa Adragão, Domingos Machado, Diogo Pais · 2018

Repensar a Ciatalgia Perante Variação Anatómica Bilateral do Nervo Isquiático, com Origem Baixa e Divisão Alta: Importância Histórica, Anatómica e Clínica Open

Fernando Ribeiro, Maria Alexandre Bettencourt-Pires, Edivaldo Xavier da Silva, Diogo Casal, Daniel Casanova‐Martínez , et al. · 2018

Introdução: O objectivo do presente estudo é o relato de um caso de variação anatómica do nervo isquiático, por origem baixa e divisão alta bilateral.Material e Métodos: Foi dissecado um cadáver feminino de 66 anos, conservado pelas técnic…

The supinator muscle and radial nerve entrapment: historical note and modern anatomical insight Open

Maria Alexandre Bettencourt Pires, Daniel Alessandro Casanova-Martinez, Diogo Casal, Edivaldo Xavier Silva-Junior, Diogo Pais , et al. · 2018

Due to its deep location, close to the elbow joint, the supinator muscle requires special dissection skills. This fact enhanced our interest for a more accurate knowledge of the anatomical relations of the muscle with the elbow joint and w…

Reconstruction of a 10-mm-long median nerve gap in an ischemic environment using autologous conduits with different patterns of blood supply: A comparative study in the rat Open

Diogo Casal, Eduarda Mota‐Silva, Inês Iria, Sara Alves, Ana Farinho , et al. · 2018

The aim of this study was to evaluate in the Wistar rat the efficacy of various autologous nerve conduits with various forms of blood supply in reconstructing a 10-mm-long gap in the median nerve (MN) under conditions of local ischemia. A …

Reconstruction of a long defect of the ulnar artery and nerve with an arterialized neurovenous free flap in a teenager: A case report and literature review Open

Diogo Casal, Diogo Pais, Eduarda Mota‐Silva, G Pelliccia, Inês Iria , et al. · 2017

There is evidence that nerve flaps are superior to nerve grafts for bridging long nerve defects. Moreover, arterialized neurovenous flaps (ANVFs) have multiple potential advantages over traditional nerve flaps in this context. This paper d…

Blood Supply to the Integument of the Abdomen of the Rat: A Surgical Perspective Open

Diogo Casal, Diogo Pais, Inês Iria, Paula A. Videira, Eduarda Mota‐Silva , et al. · 2017

Background: Many fundamental questions regarding the blood supply to the integument of the rat remain to be clarified, namely the degree of homology between rat and humans. The aim of this work was to characterize in detail the macro and m…

Optimization of an Arterialized Venous Fasciocutaneous Flap in the Abdomen of the Rat Open

Diogo Casal, Eduarda Mota‐Silva, Diogo Pais, Inês Iria, Paula A. Videira , et al. · 2017

Background: Although numerous experimental models of arterialized venous flaps (AVFs) have been proposed, no single model has gained widespread acceptance. The main aim of this work was to evaluate the survival area of AVFs produced with d…

Stab injury to the preauricular region with laceration of the external carotid artery without involvement of the facial nerve: a case report Open

Diogo Casal, G Pelliccia, Diogo Pais, Diogo Carrola-Gomes, Maria Angélica-Almeida , et al. · 2017

A Model of Free Tissue Transfer: The Rat Epigastric Free Flap Open

Diogo Casal, Diogo Pais, Inês Iria, Eduarda Mota‐Silva, M A Almeida , et al. · 2017

Free tissue transfer has been increasingly used in clinical practice since the 1970s, allowing reconstruction of complex and otherwise untreatable defects resulting from tumor extirpation, trauma, infections, malformations or burns. Free f…

A stab wound to the axilla illustrating the importance of brachial plexus anatomy in an emergency context: a case report Open

Diogo Casal, Teresa Da Cunha, Diogo Pais, Inês Iria, Maria Angélica-Almeida , et al. · 2017

Outcomes and satisfaction of two optional cadaveric dissection courses: A 3‐year prospective study Open

Diogo Pais, Diogo Casal, Luís Mascarenhas‐Lemos, Pedro C. Barata, B.J. Moxham , et al. · 2016

Teaching time dedicated to anatomy education has been reduced at many medical schools around the world, including Nova Medical School in Lisbon, Portugal. In order to minimize the effects of this reduction, the authors introduced two optio…

Patient Safety Culture in Portuguese Primary Healthcare Open

Ornelas, Diogo Pais, Paulo Sousa · 2016

Introduction: According to the European Commission more than 37 million Primary Healthcare (PHC) users suffer Adverse Events (AE). When we talk about these unintentional and undesirable events, most of the time we are dealing with acts com…

A problemática da recusa de sangue por Testemunhas de Jeová adultas e legalmente competentes Open

Daniel Rodrigues Alves, Diogo Pais · 2015

Introdução: A recusa em receber derivados do sangue a que as Testemunhas de Jeová estão submetidas levanta problemas éticos e legais relativamente ao modo como proporcionar os melhores cuidados de saúde a estes pacientes. No presente artig…

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